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Substrate specificity and kinetic mechanism of purine nucleoside phosphorylase from Mycobacterium tuberculosis

Archives of biochemistry and biophysics, 2009-06, Vol.486 (2), p.155-164

2009

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Kinetic Isotope Effects and Transition State Structure for Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase from Plasmodium falciparum

Biochemistry (Easton), 2017-12, Vol.56 (48), p.6368-6376

2017

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Inhibition and Mechanism of Plasmodium falciparum Hypoxanthine–Guanine–Xanthine Phosphoribosyltransferase

ACS chemical biology, 2022-12, Vol.17 (12), p.3407-3419

2022

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Genetic resistance to purine nucleoside phosphorylase inhibition in Plasmodium falciparum

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (9), p.2114-2119

2018

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Selective Inhibitors of Helicobacter pylori Methylthioadenosine Nucleosidase and Human Methylthioadenosine Phosphorylase

Journal of medicinal chemistry, 2019-04, Vol.62 (7), p.3286-3296

2019

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Antibacterial Strategy against H. pylori: Inhibition of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis

ACS medicinal chemistry letters, 2019-03, Vol.10 (3), p.363-366

2019

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Transition-State Analogues of Campylobacter jejuni 5′-Methylthioadenosine Nucleosidase

ACS chemical biology, 2018-11, Vol.13 (11), p.3173-3183

2018

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Continuous Fluorescence Assays for Reactions Involving Adenine

Analytical chemistry (Washington), 2016-12, Vol.88 (23), p.11860-11867

2016

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Discovery of New Inhibitors of Mycobacterium tuberculosis InhA Enzyme Using Virtual Screening and a 3D-Pharmacophore-Based Approach

Journal of chemical information and modeling, 2013-09, Vol.53 (9), p.2390-2401

2013

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MAT Gain of Activity Mutation in Helicobacter pylori Is Associated with Resistance to MTAN Transition State Analogues

ACS infectious diseases, 2023-04, Vol.9 (4), p.966-978

2023

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Synthesis of bis-Phosphate Iminoaltritol Enantiomers and Structural Characterization with Adenine Phosphoribosyltransferase

ACS chemical biology, 2018-01, Vol.13 (1), p.152-160

2018

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Transition-state inhibitors of purine salvage and other prospective enzyme targets in malaria

Future medicinal chemistry, 2013-07, Vol.5 (11), p.1341-1360

2013

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5-HTR2B and SLC6A3 as potential molecular targets of sertraline in the treatment of major depressive disorder: the use of bioinformatics and its practical implication

Network modeling and analysis in health informatics and bioinformatics (Wien), 2022-12, Vol.11 (1), p.34, Article 34

2022

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Crystallographic and docking studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis

Bioorganic & medicinal chemistry, 2010-07, Vol.18 (13), p.4769-4774

2010

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Biofilm Inhibition via Delivery of Novel Methylthioadenosine Nucleosidase Inhibitors from PVA-Tyramine Hydrogels while Supporting Mesenchymal Stromal Cell Viability

ACS biomaterials science & engineering, 2019-02, Vol.5 (2), p.748-758

2019

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Biochemical characterization of recombinant guaA-encoded guanosine monophosphate synthetase (EC 6.3.5.2) from Mycobacterium tuberculosis H37Rv strain

Archives of biochemistry and biophysics, 2012-01, Vol.517 (1), p.1-11

2012

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The kinetic mechanism of human uridine phosphorylase 1: Towards the development of enzyme inhibitors for cancer chemotherapy

Archives of biochemistry and biophysics, 2010-05, Vol.497 (1), p.35-42

2010

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Molecular, kinetic, thermodynamic, and structural analyses of Mycobacterium tuberculosis hisD-encoded metal-dependent dimeric histidinol dehydrogenase (EC 1.1.1.23)

Archives of biochemistry and biophysics, 2011-08, Vol.512 (2), p.143-153

2011

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Crystal structure and molecular dynamics studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis associated with acyclovir

Biochimie, 2012-01, Vol.94 (1), p.155-165

2012

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Structural and functional analyses of Mycobacterium tuberculosis Rv3315c-encoded metal-dependent homotetrameric cytidine deaminase

Journal of structural biology, 2010-03, Vol.169 (3), p.413-423

2010

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Molecular, kinetic, thermodynamic, and structural analyses of Mycobacterium tuberculosishisD-encoded metal-dependent dimeric histidinol dehydrogenase (EC 1.1.1.23)

Archives of biochemistry and biophysics, 2011-08, Vol.512 (2), p.143-153

2011

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Production of Bioactive Compounds vs. Recombinant Proteins

Bioprospecting of Microorganism-Based Industrial Molecules, 2021, p.125-146

2021

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Molecular, kinetic, thermodynamic, and structural analyses of Mycobacterium tuberculosis hisD-encoded metal-dependent dimeric histidinol dehydrogenase (EC 1.1.1.23)

Archives of biochemistry and biophysics, 2011-08, Vol.512 (2), p.143-153

2011

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Purine Nucleoside Phosphorylase as a Molecular Target to Develop Active Compounds Against Mycobacterium Tuberculosis

International Review of Biophysical Chemistry (IREBIC), 2010-08, Vol.1 (1), p.34

2010

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The resumption of consumption A review on tuberculosis

Memórias do Instituto Oswaldo Cruz, 2006-11, Vol.101 (7), p.697-714

2006

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Substrate specificity and kinetic mechanism of purine nucleoside phosphorylase from Mycobacterium tuberculosis

Kinetic Isotope Effects and Transition State Structure for Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase from Plasmodium falciparum

Inhibition and Mechanism of Plasmodium falciparum Hypoxanthine–Guanine–Xanthine Phosphoribosyltransferase

Genetic resistance to purine nucleoside phosphorylase inhibition in Plasmodium falciparum

Selective Inhibitors of Helicobacter pylori Methylthioadenosine Nucleosidase and Human Methylthioadenosine Phosphorylase

Antibacterial Strategy against H. pylori: Inhibition of the Radical SAM Enzyme MqnE in Menaquinone Biosynthesis

Transition-State Analogues of Campylobacter jejuni 5′-Methylthioadenosine Nucleosidase

Continuous Fluorescence Assays for Reactions Involving Adenine

Discovery of New Inhibitors of Mycobacterium tuberculosis InhA Enzyme Using Virtual Screening and a 3D-Pharmacophore-Based Approach

MAT Gain of Activity Mutation in Helicobacter pylori Is Associated with Resistance to MTAN Transition State Analogues

Synthesis of bis-Phosphate Iminoaltritol Enantiomers and Structural Characterization with Adenine Phosphoribosyltransferase

Transition-state inhibitors of purine salvage and other prospective enzyme targets in malaria

5-HTR2B and SLC6A3 as potential molecular targets of sertraline in the treatment of major depressive disorder: the use of bioinformatics and its practical implication

Crystallographic and docking studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis

Biofilm Inhibition via Delivery of Novel Methylthioadenosine Nucleosidase Inhibitors from PVA-Tyramine Hydrogels while Supporting Mesenchymal Stromal Cell Viability

Biochemical characterization of recombinant guaA-encoded guanosine monophosphate synthetase (EC 6.3.5.2) from Mycobacterium tuberculosis H37Rv strain

The kinetic mechanism of human uridine phosphorylase 1: Towards the development of enzyme inhibitors for cancer chemotherapy

Molecular, kinetic, thermodynamic, and structural analyses of Mycobacterium tuberculosis hisD-encoded metal-dependent dimeric histidinol dehydrogenase (EC 1.1.1.23)

Crystal structure and molecular dynamics studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis associated with acyclovir

Structural and functional analyses of Mycobacterium tuberculosis Rv3315c-encoded metal-dependent homotetrameric cytidine deaminase

Molecular, kinetic, thermodynamic, and structural analyses of Mycobacterium tuberculosishisD-encoded metal-dependent dimeric histidinol dehydrogenase (EC 1.1.1.23)

Production of Bioactive Compounds vs. Recombinant Proteins

Molecular, kinetic, thermodynamic, and structural analyses of Mycobacterium tuberculosis hisD-encoded metal-dependent dimeric histidinol dehydrogenase (EC 1.1.1.23)

Purine Nucleoside Phosphorylase as a Molecular Target to Develop Active Compounds Against Mycobacterium Tuberculosis

The resumption of consumption A review on tuberculosis

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