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IL-17, Produced by Lymphocytes and Neutrophils, Is Necessary for Lipopolysaccharide-Induced Airway Neutrophilia: IL-15 as a Possible Trigger

The Journal of immunology (1950), 2003-02, Vol.170 (4), p.2106-2112

2003

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Role of sphingosine 1-phosphate and lysophosphatidic acid in fibrosis

Biochimica et biophysica acta, 2013-01, Vol.1831 (1), p.228-238

2013

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Regulation of Neuregulin 1β1–Induced MUC5AC and MUC5B Expression in Human Airway Epithelium

American journal of respiratory cell and molecular biology, 2010-04, Vol.42 (4), p.472-481

2010

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Fevipiprant (QAW039), a Slowly Dissociating CRTh2 Antagonist with the Potential for Improved Clinical Efficacy

Molecular pharmacology, 2016-05, Vol.89 (5), p.593-605

2016

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Treatment with Anti–Gremlin 1 Antibody Ameliorates Chronic Hypoxia/SU5416–Induced Pulmonary Arterial Hypertension in Mice

The American journal of pathology, 2013-11, Vol.183 (5), p.1461-1473

2013

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Fevipiprant, a DP2 receptor antagonist, inhibits eosinophil migration towards mast cells

Clinical and experimental allergy, 2019-02, Vol.49 (2), p.255-257

2019

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Fevipiprant, a DP 2 receptor antagonist, inhibits eosinophil migration towards mast cells

Clinical and experimental allergy, 2019-02, Vol.49 (2), p.255-257

2019

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The Sphingosine 1-Phosphate Receptor Agonist FTY720 Differentially Affects the Sequestration of CD4+/CD25+ T-Regulatory Cells and Enhances Their Functional Activity

The Journal of immunology (1950), 2005-12, Vol.175 (12), p.7973-7980

2005

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Human Eosinophils Constitutively Express a Functional Interleukin-4 Receptor: Interleukin-4 -Induced Priming of Chemotactic Responses and Induction of PI-3 Kinase Activity

American journal of respiratory cell and molecular biology, 1998-10, Vol.19 (4), p.691-699

1998

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Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP2 Receptor Antagonist for Treatment of Asthma

ACS medicinal chemistry letters, 2017-05, Vol.8 (5), p.582-586

2017

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Pharmacokinetics, Safety, and Tolerability of Fevipiprant (QAW039), a Novel CRTh2 Receptor Antagonist: Results From 2 Randomized, Phase 1, Placebo-Controlled Studies in Healthy Volunteers

Clinical pharmacology in drug development, 2016-07, Vol.5 (4), p.306-313

2016

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IL-4 Induces Chemotaxis of Blood Eosinophils from Atopic Dermatitis Patients, but Not from Normal Individuals

Journal of investigative dermatology, 1994-06, Vol.102 (6), p.843-846

1994

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7-Azaindole-3-acetic acid derivatives: Potent and selective CRTh2 receptor antagonists

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (16), p.4794-4798

2009

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Correction to “Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP2 Receptor Antagonist for Treatment of Asthma”

ACS medicinal chemistry letters, 2017-09, Vol.8 (9), p.987-987

2017

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Correction to "Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP 2 Receptor Antagonist for Treatment of Asthma"

ACS medicinal chemistry letters, 2017-09, Vol.8 (9), p.987-987

2017

Volltextzugriff (PDF)

Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP 2 Receptor Antagonist for Treatment of Asthma

ACS medicinal chemistry letters, 2017-05, Vol.8 (5), p.582-586

2017

Volltextzugriff (PDF)

Regulation of Neuregulin 1[beta]1-Induced MUC5AC and MUC5B Expression in Human Airway Epithelium

American journal of respiratory cell and molecular biology, 2010-04, Vol.42 (4), p.472

2010

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Analysis of Signal Transduction Pathways in Human Eosinophils Activated by Chemoattractants and the T-Helper 2–Derived Cytokines Interleukin-4 and Interleukin-5

Blood, 1998-04, Vol.91 (7), p.2547-2557

1998

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Analysis of Signal Transduction Pathways in Human Eosinophils Activated by Chemoattractants and the T-Helper 2–Derived Cytokines Interleukin-4 and Interleukin-5

Blood, 1998-04, Vol.91 (7), p.2547-2557

1998

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2-Cycloalkyl phenoxyacetic acid CRTh2 receptor antagonists

Bioorganic & medicinal chemistry letters, 2007-08, Vol.17 (15), p.4347-4350

2007

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The Sphingosine 1-Phosphate Receptor Agonist FTY720 Differentially Affects the Sequestration of CD4 super(+)/CD25 super(+) T-Regulatory Cells and Enhances Their Functional Activity

Journal of Immunology, 2005-12, Vol.175 (12), p.7973-7980

2005

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Application of Ring-Opened Poly(ferrocene)s as Protective Charge Dissipation Coatings for Dielectrics

Advanced materials (Weinheim), 2000-03, Vol.12 (5), p.327-330

2000

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Adhesion molecule expression on skin endothelia in atopic dermatitis: Effects of TNF-α and IL-4

Journal of allergy and clinical immunology, 1998-09, Vol.102 (3), p.461-468

1998

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Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium

American journal of respiratory cell and molecular biology, 2010-04, Vol.42 (4), p.472-481

2010

Volltextzugriff (PDF)

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IL-17, Produced by Lymphocytes and Neutrophils, Is Necessary for Lipopolysaccharide-Induced Airway Neutrophilia: IL-15 as a Possible Trigger

Role of sphingosine 1-phosphate and lysophosphatidic acid in fibrosis

Regulation of Neuregulin 1β1–Induced MUC5AC and MUC5B Expression in Human Airway Epithelium

Fevipiprant (QAW039), a Slowly Dissociating CRTh2 Antagonist with the Potential for Improved Clinical Efficacy

Treatment with Anti–Gremlin 1 Antibody Ameliorates Chronic Hypoxia/SU5416–Induced Pulmonary Arterial Hypertension in Mice

Fevipiprant, a DP2 receptor antagonist, inhibits eosinophil migration towards mast cells

Fevipiprant, a DP 2 receptor antagonist, inhibits eosinophil migration towards mast cells

The Sphingosine 1-Phosphate Receptor Agonist FTY720 Differentially Affects the Sequestration of CD4+/CD25+ T-Regulatory Cells and Enhances Their Functional Activity

Human Eosinophils Constitutively Express a Functional Interleukin-4 Receptor: Interleukin-4 -Induced Priming of Chemotactic Responses and Induction of PI-3 Kinase Activity

Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP2 Receptor Antagonist for Treatment of Asthma

Pharmacokinetics, Safety, and Tolerability of Fevipiprant (QAW039), a Novel CRTh2 Receptor Antagonist: Results From 2 Randomized, Phase 1, Placebo-Controlled Studies in Healthy Volunteers

Discovery and characterization of NVP-QAV680, a potent and selective CRTh2 receptor antagonist suitable for clinical testing in allergic diseases

IL-4 Induces Chemotaxis of Blood Eosinophils from Atopic Dermatitis Patients, but Not from Normal Individuals

7-Azaindole-3-acetic acid derivatives: Potent and selective CRTh2 receptor antagonists

Correction to “Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP2 Receptor Antagonist for Treatment of Asthma”

Correction to "Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP 2 Receptor Antagonist for Treatment of Asthma"

Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP 2 Receptor Antagonist for Treatment of Asthma

Regulation of Neuregulin 1[beta]1-Induced MUC5AC and MUC5B Expression in Human Airway Epithelium

Analysis of Signal Transduction Pathways in Human Eosinophils Activated by Chemoattractants and the T-Helper 2–Derived Cytokines Interleukin-4 and Interleukin-5

Analysis of Signal Transduction Pathways in Human Eosinophils Activated by Chemoattractants and the T-Helper 2–Derived Cytokines Interleukin-4 and Interleukin-5

2-Cycloalkyl phenoxyacetic acid CRTh2 receptor antagonists

The Sphingosine 1-Phosphate Receptor Agonist FTY720 Differentially Affects the Sequestration of CD4 super(+)/CD25 super(+) T-Regulatory Cells and Enhances Their Functional Activity

Application of Ring-Opened Poly(ferrocene)s as Protective Charge Dissipation Coatings for Dielectrics

Adhesion molecule expression on skin endothelia in atopic dermatitis: Effects of TNF-α and IL-4

Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium

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