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Leptin gene transfer in the hypothalamus enhances longevity in adult monogenic mutant mice in the absence of circulating leptin

Neurobiology of aging, 2007-10, Vol.28 (10), p.1594-1604

2007

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Leptin Modulates Orexigenic Effects of Ghrelin and Attenuates Adiponectin and Insulin Levels and Selectively the Dark-Phase Feeding as Revealed by Central Leptin Gene Therapy

Endocrinology (Philadelphia), 2004-09, Vol.145 (9), p.4176-4184

2004

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Inhibition of p66ShcA redox activity in cardiac muscle cells attenuates hyperglycemia-induced oxidative stress and apoptosis

American journal of physiology. Heart and circulatory physiology, 2009-02, Vol.296 (2), p.H380-H388

2009

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Leptin Expression in Hypothalamic PVN Reverses Dietary Obesity and Hyperinsulinemia but Stimulates Ghrelin

Obesity (Silver Spring, Md.), 2003-12, Vol.11 (12), p.1463-1470

2003

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High-fat Diet-induced Ultradian Leptin and Insulin Hypersecretion are Absent in Obesity-resistant Rats

Obesity (Silver Spring, Md.), 2005-06, Vol.13 (6), p.991-999

2005

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Central leptin differentially modulates ultradian secretory patterns of insulin, leptin and ghrelin independent of effects on food intake and body weight

Peptides (New York, N.Y. : 1980), 2005-12, Vol.26 (12), p.2559-2566

2005

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Low abundance of NPY in the hypothalamus can produce hyperphagia and obesity

Peptides (New York, N.Y. : 1980), 2007-02, Vol.28 (2), p.475-479

2007

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Evidence of NPY Y5 receptor involvement in food intake elicited by orexin A in sated rats

Peptides (New York, N.Y. : 1980), 2000-10, Vol.21 (10), p.1557-1560

2000

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Food intake elicited by central administration of orexins/hypocretins: identification of hypothalamic sites of action

Brain research, 1999-09, Vol.842 (2), p.473-477

1999

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Leptin increases osteoblast-specific osteocalcin release through a hypothalamic relay

Peptides (New York, N.Y. : 1980), 2009-05, Vol.30 (5), p.967-973

2009

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Increased leptin expression selectively in the hypothalamus suppresses inflammatory markers CRP and IL-6 in leptin-deficient diabetic obese mice

Peptides (New York, N.Y. : 1980), 2008-04, Vol.29 (4), p.593-598

2008

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Leptin and ciliary neurotropic factor (CNTF) inhibit fasting-induced suppression of luteinizing hormone release in rats: role of neuropeptide Y

Neuroscience letters, 1998-01, Vol.240 (1), p.45-49

1998

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Rhythmic, reciprocal ghrelin and leptin signaling: new insight in the development of obesity

Regulatory Peptides, 2003-03, Vol.111 (1), p.1-11

2003

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Long-term suppression of weight gain, adiposity, and serum insulin by central leptin gene therapy in prepubertal rats: Effects on serum ghrelin and appetite-regulating genes

Pediatric research, 2002-08, Vol.52 (2), p.189-198

2002

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Central leptin gene therapy blocks high-fat diet-induced weight gain, hyperleptinemia, and hyperinsulinemia increase in serum ghrelin levels

Diabetes (New York, N.Y.), 2002-06, Vol.51 (6), p.1729-1736

2002

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Central Leptin Gene Therapy Blocks Ovariectomy-Induced Adiposity

Obesity (Silver Spring, Md.), 2006-08, Vol.14 (8), p.1312-1319

2006

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Hypothalamic clamp on insulin release by leptin-transgene expression

Peptides (New York, N.Y. : 1980), 2006-12, Vol.27 (12), p.3245-3254

2006

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The hypothalamic paraventricular nucleus is not essential for orexigenic NPY or anorexigenic melanocortin action

Peptides (New York, N.Y. : 1980), 2006-09, Vol.27 (9), p.2239-2248

2006

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Increased Leptin Expression in the Dorsal Vagal Complex Suppresses Adiposity without Affecting Energy Intake and Metabolic Hormones

Obesity (Silver Spring, Md.), 2006-06, Vol.14 (6), p.1003-1009

2006

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Comparing the hypothalamic and extrahypothalamic actions of endogenous hyperleptinemia

Proceedings of the National Academy of Sciences - PNAS, 1999-08, Vol.96 (18), p.10373-10378

1999

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Perigestational suppression of weight gain with central leptin gene therapy results in lower weight F1 generation

Peptides (New York, N.Y. : 1980), 2005-07, Vol.26 (7), p.1176-1187

2005

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Disruption in neuropeptide Y and leptin signaling in obese ventromedial hypothalamic-lesioned rats

Brain research, 1999-01, Vol.816 (1), p.38-46

1999

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Interacting Appetite-Regulating Pathways in the Hypothalamic Regulation of Body Weight

Endocrine reviews, 1999-02, Vol.20 (1), p.68-100

Kalra, S. P.

1999

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Increased receptor sensitivity to neuropeptide Y in the hypothalamus may underlie transient hyperphagia and body weight gain

Regulatory peptides, 1997-10, Vol.72 (2), p.121-130

1997

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The mPVN mediates blockade of NPY-induced feeding by a Y5 receptor antagonist: a c-FOS analysis

Peptides (New York, N.Y. : 1980), 2001-03, Vol.22 (3), p.507-514

2001

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Leptin gene transfer in the hypothalamus enhances longevity in adult monogenic mutant mice in the absence of circulating leptin

Leptin Modulates Orexigenic Effects of Ghrelin and Attenuates Adiponectin and Insulin Levels and Selectively the Dark-Phase Feeding as Revealed by Central Leptin Gene Therapy

Inhibition of p66ShcA redox activity in cardiac muscle cells attenuates hyperglycemia-induced oxidative stress and apoptosis

Leptin Expression in Hypothalamic PVN Reverses Dietary Obesity and Hyperinsulinemia but Stimulates Ghrelin

High-fat Diet-induced Ultradian Leptin and Insulin Hypersecretion are Absent in Obesity-resistant Rats

Central leptin differentially modulates ultradian secretory patterns of insulin, leptin and ghrelin independent of effects on food intake and body weight

Low abundance of NPY in the hypothalamus can produce hyperphagia and obesity

Evidence of NPY Y5 receptor involvement in food intake elicited by orexin A in sated rats

Food intake elicited by central administration of orexins/hypocretins: identification of hypothalamic sites of action

Leptin increases osteoblast-specific osteocalcin release through a hypothalamic relay

Increased leptin expression selectively in the hypothalamus suppresses inflammatory markers CRP and IL-6 in leptin-deficient diabetic obese mice

Leptin and ciliary neurotropic factor (CNTF) inhibit fasting-induced suppression of luteinizing hormone release in rats: role of neuropeptide Y

Rhythmic, reciprocal ghrelin and leptin signaling: new insight in the development of obesity

Long-term suppression of weight gain, adiposity, and serum insulin by central leptin gene therapy in prepubertal rats: Effects on serum ghrelin and appetite-regulating genes

Central leptin gene therapy blocks high-fat diet-induced weight gain, hyperleptinemia, and hyperinsulinemia increase in serum ghrelin levels

Central Leptin Gene Therapy Blocks Ovariectomy-Induced Adiposity

Hypothalamic clamp on insulin release by leptin-transgene expression

The hypothalamic paraventricular nucleus is not essential for orexigenic NPY or anorexigenic melanocortin action

Increased Leptin Expression in the Dorsal Vagal Complex Suppresses Adiposity without Affecting Energy Intake and Metabolic Hormones

Comparing the hypothalamic and extrahypothalamic actions of endogenous hyperleptinemia

Perigestational suppression of weight gain with central leptin gene therapy results in lower weight F1 generation

Disruption in neuropeptide Y and leptin signaling in obese ventromedial hypothalamic-lesioned rats

Interacting Appetite-Regulating Pathways in the Hypothalamic Regulation of Body Weight

Increased receptor sensitivity to neuropeptide Y in the hypothalamus may underlie transient hyperphagia and body weight gain

The mPVN mediates blockade of NPY-induced feeding by a Y5 receptor antagonist: a c-FOS analysis

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