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Shikonin targets cytosolic thioredoxin reductase to induce ROS-mediated apoptosis in human promyelocytic leukemia HL-60 cells

Free radical biology & medicine, 2014-05, Vol.70, p.182-193

2014

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Targeting Thioredoxin Reductase by Parthenolide Contributes to Inducing Apoptosis of HeLa Cells

The Journal of biological chemistry, 2016-05, Vol.291 (19), p.10021-10031

2016

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Highly Selective Off–On Fluorescent Probe for Imaging Thioredoxin Reductase in Living Cells

Journal of the American Chemical Society, 2014-01, Vol.136 (1), p.226-233

2014

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Inhibition of thioredoxin reductase by alantolactone prompts oxidative stress-mediated apoptosis of HeLa cells

Biochemical pharmacology, 2016-02, Vol.102, p.34-44

2016

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Dual protection of hydroxytyrosol, an olive oil polyphenol, against oxidative damage in PC12 cells

Food & function, 2015-06, Vol.6 (6), p.2091-2100

2015

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Natural diterpenoid eriocalyxin B covalently modifies glutathione and selectively inhibits thioredoxin reductase inducing potent oxidative stress-mediated apoptosis in colorectal carcinoma RKO cells

Free radical biology & medicine, 2021-12, Vol.177, p.15-23

2021

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Curcumin targeting the thioredoxin system elevates oxidative stress in HeLa cells

Toxicology and applied pharmacology, 2012-08, Vol.262 (3), p.341-348

2012

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Natural Products: A Promising Therapeutics for Targeting Tumor Angiogenesis

Frontiers in oncology, 2021-10, Vol.11, p.772915-772915

2021

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Fluorescent Probes for Mammalian Thioredoxin Reductase: Mechanistic Analysis, Construction Strategies, and Future Perspectives

Biosensors (Basel), 2023-08, Vol.13 (8), p.811

2023

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Non-coding RNAs in Regulating Tumor Angiogenesis

Frontiers in cell and developmental biology, 2021-09, Vol.9, p.751578-751578

2021

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Modified TLC bioautographic method for screening acetylcholinesterase inhibitors from plant extracts

Journal of separation science, 2009-09, Vol.32 (18), p.3257-3259

2009

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Natural Molecules Targeting Thioredoxin System and Their Therapeutic Potential

Antioxidants & redox signaling, 2021-05, Vol.34 (14), p.1083

2021

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Synthesis of Xanthohumol Analogues and Discovery of Potent Thioredoxin Reductase Inhibitor as Potential Anticancer Agent

Journal of medicinal chemistry, 2015-02, Vol.58 (4), p.1795-1805

2015

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Redox-Dependent Copper Carrier Promotes Cellular Copper Uptake and Oxidative Stress-Mediated Apoptosis of Cancer Cells

ACS applied materials & interfaces, 2018-10, Vol.10 (39), p.33010-33021

2018

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Small molecules regulating reactive oxygen species homeostasis for cancer therapy

Medicinal research reviews, 2021-01, Vol.41 (1), p.342-394

2021

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Dithiaarsanes Induce Oxidative Stress-Mediated Apoptosis in HL-60 Cells by Selectively Targeting Thioredoxin Reductase

Journal of medicinal chemistry, 2014-06, Vol.57 (12), p.5203-5211

2014

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Targeting thioredoxin reductase by deoxyelephantopin from Elephantopus scaber triggers cancer cell apoptosis

Archives of biochemistry and biophysics, 2021-10, Vol.711, p.109028-109028, Article 109028

2021

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A selective and sensitive fluorescence probe for imaging endogenous zinc in living cells

Tetrahedron, 2013-01, Vol.69 (1), p.15-21

2013

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Activation of Nrf2 target enzymes conferring protection against oxidative stress in PC12 cells by ginger principal constituent 6-shogaol

Food & function, 2015-08, Vol.6 (8), p.2813-2823

2015

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Activation of the Phase II Enzymes for Neuroprotection by Ginger Active Constituent 6‑Dehydrogingerdione in PC12 Cells

Journal of agricultural and food chemistry, 2014-06, Vol.62 (24), p.5507-5518

2014

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Rheumatoid arthritis drug sinomenine induces apoptosis of cervical tumor cells by targeting thioredoxin reductase in vitro and in vivo

Bioorganic chemistry, 2022-05, Vol.122, p.105711-105711, Article 105711

2022

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Analysis of the main active ingredients and bioactivities of essential oil from Osmanthus fragrans Var. thunbergii using a complex network approach

BMC systems biology, 2017-12, Vol.11 (1), p.144-144, Article 144

2017

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The influence of duckweed species diversity on ecophysiological tolerance to copper exposure

Aquatic toxicology, 2015-07, Vol.164, p.92-98

2015

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Targeting ubiquitin conjugating enzyme UbcH5b by a triterpenoid PC3-15 from Schisandra plants sensitizes triple-negative breast cancer cells to lapatinib

Cancer letters, 2021-04, Vol.504, p.125-136

2021

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Highly oxygenated caryophyllene-type and drimane-type sesquiterpenes from Pestalotiopsis adusta, an endophytic fungus of Sinopodophyllum hexandrum

RSC advances, 2017, Vol.7 (46), p.29071-29079

2017

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Shikonin targets cytosolic thioredoxin reductase to induce ROS-mediated apoptosis in human promyelocytic leukemia HL-60 cells

Targeting Thioredoxin Reductase by Parthenolide Contributes to Inducing Apoptosis of HeLa Cells

Highly Selective Off–On Fluorescent Probe for Imaging Thioredoxin Reductase in Living Cells

Inhibition of thioredoxin reductase by alantolactone prompts oxidative stress-mediated apoptosis of HeLa cells

Dual protection of hydroxytyrosol, an olive oil polyphenol, against oxidative damage in PC12 cells

Natural diterpenoid eriocalyxin B covalently modifies glutathione and selectively inhibits thioredoxin reductase inducing potent oxidative stress-mediated apoptosis in colorectal carcinoma RKO cells

Curcumin targeting the thioredoxin system elevates oxidative stress in HeLa cells

Natural Products: A Promising Therapeutics for Targeting Tumor Angiogenesis

Fluorescent Probes for Mammalian Thioredoxin Reductase: Mechanistic Analysis, Construction Strategies, and Future Perspectives

Non-coding RNAs in Regulating Tumor Angiogenesis

Modified TLC bioautographic method for screening acetylcholinesterase inhibitors from plant extracts

Natural Molecules Targeting Thioredoxin System and Their Therapeutic Potential

Synthesis of Xanthohumol Analogues and Discovery of Potent Thioredoxin Reductase Inhibitor as Potential Anticancer Agent

Redox-Dependent Copper Carrier Promotes Cellular Copper Uptake and Oxidative Stress-Mediated Apoptosis of Cancer Cells

Small molecules regulating reactive oxygen species homeostasis for cancer therapy

Dithiaarsanes Induce Oxidative Stress-Mediated Apoptosis in HL-60 Cells by Selectively Targeting Thioredoxin Reductase

Targeting thioredoxin reductase by deoxyelephantopin from Elephantopus scaber triggers cancer cell apoptosis

A selective and sensitive fluorescence probe for imaging endogenous zinc in living cells

Activation of Nrf2 target enzymes conferring protection against oxidative stress in PC12 cells by ginger principal constituent 6-shogaol

Activation of the Phase II Enzymes for Neuroprotection by Ginger Active Constituent 6‑Dehydrogingerdione in PC12 Cells

Rheumatoid arthritis drug sinomenine induces apoptosis of cervical tumor cells by targeting thioredoxin reductase in vitro and in vivo

Analysis of the main active ingredients and bioactivities of essential oil from Osmanthus fragrans Var. thunbergii using a complex network approach

The influence of duckweed species diversity on ecophysiological tolerance to copper exposure

Targeting ubiquitin conjugating enzyme UbcH5b by a triterpenoid PC3-15 from Schisandra plants sensitizes triple-negative breast cancer cells to lapatinib

Highly oxygenated caryophyllene-type and drimane-type sesquiterpenes from Pestalotiopsis adusta, an endophytic fungus of Sinopodophyllum hexandrum

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