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Daily variation of gene expression in diverse rat tissues

PloS one, 2018-05, Vol.13 (5), p.e0197258-e0197258

2018

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Physiologically Based Pharmacokinetic Modeling Involving Nonlinear Plasma and Tissue Binding: Application to Prednisolone and Prednisone in Rats

The Journal of pharmacology and experimental therapeutics, 2020-11, Vol.375 (2), p.385-396

2020

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Modeling Sex Differences in Anti-inflammatory Effects of Dexamethasone in Arthritic Rats

Pharmaceutical research, 2018-11, Vol.35 (11), p.203-9, Article 203

2018

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Physiologically Based Pharmacokinetics of Dexamethasone in Rats

Drug metabolism and disposition, 2020-09, Vol.48 (9), p.811-818

2020

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Modeling Corticosteroid Pharmacokinetics and Pharmacodynamics, Part II: Sex Differences in Methylprednisolone Pharmacokinetics and Corticosterone Suppression

The Journal of pharmacology and experimental therapeutics, 2019-08, Vol.370 (2), p.327-336

2019

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Modeling Corticosteroid Pharmacokinetics and Pharmacodynamics, Part I: Determination and Prediction of Dexamethasone and Methylprednisolone Tissue Binding in the Rat

The Journal of pharmacology and experimental therapeutics, 2019-08, Vol.370 (2), p.318-326

2019

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Adipose tissue deficiency and chronic inflammation in diabetic Goto-Kakizaki rats

PloS one, 2011-02, Vol.6 (2), p.e17386-e17386

2011

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Circadian rhythms in gene expression: Relationship to physiology, disease, drug disposition and drug action

Advanced drug delivery reviews, 2010-07, Vol.62 (9), p.904-917

2010

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Modeling Corticosteroid Pharmacokinetics and Pharmacodynamics, Part III: Estrous Cycle and Estrogen Receptor-Dependent Antagonism of Glucocorticoid-Induced Leucine Zipper (GILZ) Enhancement by Corticosteroids

The Journal of pharmacology and experimental therapeutics, 2019-08, Vol.370 (2), p.337-349

2019

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Modeling circadian variability of core-clock and clock-controlled genes in four tissues of the rat

PloS one, 2018-06, Vol.13 (6), p.e0197534-e0197534

2018

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Interrelationships between Infliximab and Recombinant Tumor Necrosis Factor- α in Plasma Using Minimal Physiologically Based Pharmacokinetic Models

Drug metabolism and disposition, 2017-07, Vol.45 (7), p.790-797

2017

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Interactions of Tofacitinib and Dexamethasone on Lymphocyte Proliferation

Pharmaceutical research, 2020-06, Vol.37 (6), p.105, Article 105

2020

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Light-dark oscillations in the lung transcriptome: implications for lung homeostasis, repair, metabolism, disease, and drug action

Journal of applied physiology (1985), 2011-06, Vol.110 (6), p.1732-1747

2011

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Characterization and Interspecies Scaling of rhTNF- α Pharmacokinetics with Minimal Physiologically Based Pharmacokinetic Models

Drug metabolism and disposition, 2017-07, Vol.45 (7), p.798-806

2017

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Mechanistic Multi-Tissue Modeling of Glucocorticoid-Induced Leucine Zipper Regulation: Integrating Circadian Gene Expression with Receptor-Mediated Corticosteroid Pharmacodynamics

The Journal of pharmacology and experimental therapeutics, 2017-10, Vol.363 (1), p.45-57

2017

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Modeling Corticosteroid Pharmacogenomics and Proteomics in Rat Liver

The Journal of pharmacology and experimental therapeutics, 2018-10, Vol.367 (1), p.168-183

2018

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Biodistribution of etanercept to tissues and sites of inflammation in arthritic rats

Drug metabolism and disposition, 2015-06, Vol.43 (6), p.898-907

2015

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Meta-modeling of methylprednisolone effects on glucose regulation in rats

PloS one, 2013-12, Vol.8 (12), p.e81679

2013

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Functional proteomic analysis of corticosteroid pharmacodynamics in rat liver: Relationship to hepatic stress, signaling, energy regulation, and drug metabolism

Journal of proteomics, 2017-05, Vol.160, p.84-105

2017

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Modeling Combined Anti-Inflammatory Effects of Dexamethasone and Tofacitinib in Arthritic Rats

The AAPS journal, 2019-07, Vol.21 (5), p.93-93, Article 93

2019

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Modeling Combined Immunosuppressive and Anti-inflammatory Effects of Dexamethasone and Naproxen in Rats Predicts the Steroid-Sparing Potential of Naproxen

Drug metabolism and disposition, 2017-07, Vol.45 (7), p.834-845

2017

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Assessment of Pharmacologic Area Under the Curve When Baselines are Variable

Pharmaceutical research, 2011-05, Vol.28 (5), p.1081-1089

2011

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Highly Multiplexed and Reproducible Ion-Current-Based Strategy for Large-Scale Quantitative Proteomics and the Application to Protein Expression Dynamics Induced by Methylprednisolone in 60 Rats

Analytical chemistry (Washington), 2014-08, Vol.86 (16), p.8149-8157

2014

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Modeling Sex Differences in Pharmacokinetics, Pharmacodynamics, and Disease Progression Effects of Naproxen in Rats with Collagen-Induced Arthritis

Drug metabolism and disposition, 2017-05, Vol.45 (5), p.484-491

2017

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Circadian signatures in rat liver: from gene expression to pathways

BMC bioinformatics, 2010-11, Vol.11 (1), p.540-540, Article 540

2010

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Daily variation of gene expression in diverse rat tissues

Physiologically Based Pharmacokinetic Modeling Involving Nonlinear Plasma and Tissue Binding: Application to Prednisolone and Prednisone in Rats

Modeling Sex Differences in Anti-inflammatory Effects of Dexamethasone in Arthritic Rats

Physiologically Based Pharmacokinetics of Dexamethasone in Rats

Modeling Corticosteroid Pharmacokinetics and Pharmacodynamics, Part II: Sex Differences in Methylprednisolone Pharmacokinetics and Corticosterone Suppression

Modeling Corticosteroid Pharmacokinetics and Pharmacodynamics, Part I: Determination and Prediction of Dexamethasone and Methylprednisolone Tissue Binding in the Rat

Adipose tissue deficiency and chronic inflammation in diabetic Goto-Kakizaki rats

Circadian rhythms in gene expression: Relationship to physiology, disease, drug disposition and drug action

Modeling Corticosteroid Pharmacokinetics and Pharmacodynamics, Part III: Estrous Cycle and Estrogen Receptor-Dependent Antagonism of Glucocorticoid-Induced Leucine Zipper (GILZ) Enhancement by Corticosteroids

Modeling circadian variability of core-clock and clock-controlled genes in four tissues of the rat

Interrelationships between Infliximab and Recombinant Tumor Necrosis Factor- α in Plasma Using Minimal Physiologically Based Pharmacokinetic Models

Interactions of Tofacitinib and Dexamethasone on Lymphocyte Proliferation

Light-dark oscillations in the lung transcriptome: implications for lung homeostasis, repair, metabolism, disease, and drug action

Characterization and Interspecies Scaling of rhTNF- α Pharmacokinetics with Minimal Physiologically Based Pharmacokinetic Models

Mechanistic Multi-Tissue Modeling of Glucocorticoid-Induced Leucine Zipper Regulation: Integrating Circadian Gene Expression with Receptor-Mediated Corticosteroid Pharmacodynamics

Modeling Corticosteroid Pharmacogenomics and Proteomics in Rat Liver

Biodistribution of etanercept to tissues and sites of inflammation in arthritic rats

Meta-modeling of methylprednisolone effects on glucose regulation in rats

Functional proteomic analysis of corticosteroid pharmacodynamics in rat liver: Relationship to hepatic stress, signaling, energy regulation, and drug metabolism

Modeling Combined Anti-Inflammatory Effects of Dexamethasone and Tofacitinib in Arthritic Rats

Modeling Combined Immunosuppressive and Anti-inflammatory Effects of Dexamethasone and Naproxen in Rats Predicts the Steroid-Sparing Potential of Naproxen

Assessment of Pharmacologic Area Under the Curve When Baselines are Variable

Highly Multiplexed and Reproducible Ion-Current-Based Strategy for Large-Scale Quantitative Proteomics and the Application to Protein Expression Dynamics Induced by Methylprednisolone in 60 Rats

Modeling Sex Differences in Pharmacokinetics, Pharmacodynamics, and Disease Progression Effects of Naproxen in Rats with Collagen-Induced Arthritis

Circadian signatures in rat liver: from gene expression to pathways

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