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Relationship between Initial Vancomycin Concentration-Time Profile and Nephrotoxicity among Hospitalized Patients

Clinical infectious diseases, 2009-08, Vol.49 (4), p.507-514

2009

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Antimicrobial pharmacodynamics: critical interactions of 'bug and drug'

Nature reviews. Microbiology, 2004-04, Vol.2 (4), p.289-300

Drusano, George L

2004

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Are Vancomycin Trough Concentrations Adequate for Optimal Dosing?

Antimicrobial Agents and Chemotherapy, 2014-01, Vol.58 (1), p.309-316

2014

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Dosing Regimen Matters: the Importance of Early Intervention and Rapid Attainment of the Pharmacokinetic/Pharmacodynamic Target

Antimicrobial Agents and Chemotherapy, 2012-06, Vol.56 (6), p.2795-2805

2012

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Pre-clinical in vitro infection models

Current opinion in pharmacology, 2017-10, Vol.36, p.100-106

Drusano, George L

2017

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Piperacillin-Tazobactam for Pseudomonas aeruginosa Infection: Clinical Implications of an Extended-Infusion Dosing Strategy

Clinical infectious diseases, 2007-02, Vol.44 (3), p.357-363

2007

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Analysis of combination drug therapy to develop regimens with shortened duration of treatment for tuberculosis

PloS one, 2014-07, Vol.9 (7), p.e101311

2014

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Daptomycin Exposure and the Probability of Elevations in the Creatine Phosphokinase Level: Data from a Randomized Trial of Patients with Bacteremia and Endocarditis

Clinical infectious diseases, 2010-06, Vol.50 (12), p.1568-1574

2010

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Rational design of a new antibiotic class for drug-resistant infections

Nature (London), 2021-09, Vol.597 (7878), p.698-702

2021

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Generating Robust and Informative Nonclinical In Vitro and In Vivo Bacterial Infection Model Efficacy Data To Support Translation to Humans

Antimicrobial agents and chemotherapy, 2019-05, Vol.63 (5)

2019

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Vancomycin Exposure in Patients With Methicillin-Resistant Staphylococcus aureus Bloodstream Infections: How Much Is Enough?

Clinical infectious diseases, 2014-09, Vol.59 (5), p.666-675

2014

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Pharmacokinetics-Pharmacodynamics of Antimicrobial Therapy: It's Not Just for Mice Anymore

Clinical infectious diseases, 2007-01, Vol.44 (1), p.79-86

2007

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Stepping Off the Resistance Treadmill

The Journal of infectious diseases, 2017-07, Vol.216 (2), p.150-152

Drusano, George L.

2017

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Why Molnupiravir Fails in Hospitalized Patients

mBio, 2022-12, Vol.13 (6), p.e0291622

2022

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Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions

The Lancet infectious diseases, 2014-06, Vol.14 (6), p.498-509

2014

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Back to the Future: Using Aminoglycosides Again and How to Dose Them Optimally

Clinical infectious diseases, 2007-09, Vol.45 (6), p.753-760

2007

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Effect of Linezolid plus Bedaquiline against Mycobacterium tuberculosis in Log Phase, Acid Phase, and Nonreplicating-Persister Phase in an In Vitro Assay

Antimicrobial agents and chemotherapy, 2018-08, Vol.62 (8)

2018

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First Penicillin-Binding Protein Occupancy Patterns of β-Lactams and β-Lactamase Inhibitors in Klebsiella pneumoniae

Antimicrobial agents and chemotherapy, 2018-06, Vol.62 (6)

2018

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Polymyxin Susceptibility Testing and Interpretive Breakpoints: Recommendations from the United States Committee on Antimicrobial Susceptibility Testing (USCAST)

Antimicrobial agents and chemotherapy, 2020-01, Vol.64 (2)

2020

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Individualized Patient Care Through Model-Informed Precision Dosing: Reflections on Training Future Practitioners

The AAPS journal, 2022-11, Vol.24 (6), p.117, Article 117

2022

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Cerebrospinal pharmacokinetic and pharmacodynamic analysis of efficacy of meropenem in paediatric patients with bacterial meningitis

International journal of antimicrobial agents, 2019-09, Vol.54 (3), p.292-300

2019

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Concentration-Dependent Mycobacterium tuberculosis Killing and Prevention of Resistance by Rifampin

Antimicrobial Agents and Chemotherapy, 2007-11, Vol.51 (11), p.3781-3788

2007

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Inoculum-Based Dosing: A Novel Concept for Combining Time with Concentration-Dependent Antibiotics to Optimize Clinical and Microbiological Outcomes in Severe Gram Negative Sepsis

Antibiotics (Basel), 2023-10, Vol.12 (11), p.1581

2023

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Selection of a Moxifloxacin Dose That Suppresses Drug Resistance in Mycobacterium tuberculosis, by Use of an In Vitro Pharmacodynamic Infection Model and Mathematical Modeling

The Journal of infectious diseases, 2004-11, Vol.190 (9), p.1642-1651

2004

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Conserving antibiotics for the future: New ways to use old and new drugs from a pharmacokinetic and pharmacodynamic perspective

Drug resistance updates, 2011-04, Vol.14 (2), p.107-117

2011

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Relationship between Initial Vancomycin Concentration-Time Profile and Nephrotoxicity among Hospitalized Patients

Antimicrobial pharmacodynamics: critical interactions of 'bug and drug'

Are Vancomycin Trough Concentrations Adequate for Optimal Dosing?

Dosing Regimen Matters: the Importance of Early Intervention and Rapid Attainment of the Pharmacokinetic/Pharmacodynamic Target

Pre-clinical in vitro infection models

Piperacillin-Tazobactam for Pseudomonas aeruginosa Infection: Clinical Implications of an Extended-Infusion Dosing Strategy

Analysis of combination drug therapy to develop regimens with shortened duration of treatment for tuberculosis

Daptomycin Exposure and the Probability of Elevations in the Creatine Phosphokinase Level: Data from a Randomized Trial of Patients with Bacteremia and Endocarditis

Rational design of a new antibiotic class for drug-resistant infections

Generating Robust and Informative Nonclinical In Vitro and In Vivo Bacterial Infection Model Efficacy Data To Support Translation to Humans

Vancomycin Exposure in Patients With Methicillin-Resistant Staphylococcus aureus Bloodstream Infections: How Much Is Enough?

Pharmacokinetics-Pharmacodynamics of Antimicrobial Therapy: It's Not Just for Mice Anymore

Stepping Off the Resistance Treadmill

Why Molnupiravir Fails in Hospitalized Patients

Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions

Back to the Future: Using Aminoglycosides Again and How to Dose Them Optimally

Effect of Linezolid plus Bedaquiline against Mycobacterium tuberculosis in Log Phase, Acid Phase, and Nonreplicating-Persister Phase in an In Vitro Assay

First Penicillin-Binding Protein Occupancy Patterns of β-Lactams and β-Lactamase Inhibitors in Klebsiella pneumoniae

Polymyxin Susceptibility Testing and Interpretive Breakpoints: Recommendations from the United States Committee on Antimicrobial Susceptibility Testing (USCAST)

Individualized Patient Care Through Model-Informed Precision Dosing: Reflections on Training Future Practitioners

Cerebrospinal pharmacokinetic and pharmacodynamic analysis of efficacy of meropenem in paediatric patients with bacterial meningitis

Concentration-Dependent Mycobacterium tuberculosis Killing and Prevention of Resistance by Rifampin

Inoculum-Based Dosing: A Novel Concept for Combining Time with Concentration-Dependent Antibiotics to Optimize Clinical and Microbiological Outcomes in Severe Gram Negative Sepsis

Selection of a Moxifloxacin Dose That Suppresses Drug Resistance in Mycobacterium tuberculosis, by Use of an In Vitro Pharmacodynamic Infection Model and Mathematical Modeling

Conserving antibiotics for the future: New ways to use old and new drugs from a pharmacokinetic and pharmacodynamic perspective

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