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What Evolutionary Evidence Implies About the Identity of the Mechanoelectrical Couplers in Vascular Smooth Muscle Cells

Physiology (Bethesda, Md.), 2021-09, Vol.36 (5), p.292-306

Drummond, Heather A

2021

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βENaC and ASIC2 associate in VSMCs to mediate pressure-induced constriction in the renal afferent arteriole

American journal of physiology. Renal physiology, 2022-05, Vol.322 (5), p.F498-F511

2022

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Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3β Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) α

The Journal of biological chemistry, 2016-11, Vol.291 (48), p.25179-25191

2016

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Expression of Exogenous Epithelial Sodium Channel Beta Subunit in the Mouse Middle Cerebral Artery Increases Pressure-Induced Constriction

American journal of hypertension, 2021-11, Vol.34 (11), p.1227-1235

2021

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Pressure-induced constriction of the middle cerebral artery is abolished in TrpC6 knockout mice

American journal of physiology. Heart and circulatory physiology, 2020-07, Vol.319 (1), p.H42-H50

2020

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Epithelial Sodium Channels in Monocyte‐Macrophage Migration and Regulation by Pro‐inflammatory Cytokines TNFα and IFNγ

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Epithelial sodium channels in macrophage migration and polarization: role of proinflammatory cytokines TNFα and IFNγ

American journal of physiology. Regulatory, integrative and comparative physiology, 2022-11, Vol.323 (5), p.R763-R775

2022

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Placental ischemia-induced increases in brain water content and cerebrovascular permeability: role of TNF-α

American journal of physiology. Regulatory, integrative and comparative physiology, 2015-12, Vol.309 (11), p.R1425-R1431

2015

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Reduced uterine perfusion pressure induces hypertension in the pregnant mouse

American journal of physiology. Regulatory, integrative and comparative physiology, 2014-12, Vol.307 (11), p.R1353-R1357

2014

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The Ion Channel ASIC2 Is Required for Baroreceptor and Autonomic Control of the Circulation

Neuron (Cambridge, Mass.), 2009-12, Vol.64 (6), p.885-897

2009

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Interleukin-17 Reduces βENaC via MAPK Signaling in Vascular Smooth Muscle Cells

International journal of molecular sciences, 2020-04, Vol.21 (8), p.2953

2020

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Tumor necrosis factor-α impairs cerebral blood flow in pregnant rats: role of vascular β-epithelial Na + channel

American journal of physiology. Heart and circulatory physiology, 2020-04, Vol.318 (4), p.H1018-H1027

2020

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Bone marrow monocytes and macrophages from mice lacking βENaC and ASIC2 have a reduced chemotactic migration response and polarization

Physiological reports, 2024-07, Vol.12 (14), p.e16139

2024

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Tumor Necrosis Factor-α Antagonist Etanercept Decreases Blood Pressure and Protects the Kidney in a Mouse Model of Systemic Lupus Erythematosus

Hypertension (Dallas, Tex. 1979), 2010-10, Vol.56 (4), p.643-649

2010

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CD133+ melanoma subpopulation acquired resistance to caffeic acid phenethyl ester-induced apoptosis is attributed to the elevated expression of ABCB5: Significance for melanoma treatment

Cancer letters, 2015-02, Vol.357 (1), p.83-104

2015

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A New Trick for an Old Dogma: ENaC Proteins as Mechanotransducers in Vascular Smooth Muscle

Physiology (Bethesda, Md.), 2008-02, Vol.23 (1), p.23-31

2008

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Role of carbon monoxide in kidney function: is a little carbon monoxide good for the kidney?

Current pharmaceutical biotechnology, 2012-05, Vol.13 (6), p.819

2012

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βENaC is a molecular component of a VSMC mechanotransducer that contributes to renal blood flow regulation, protection from renal injury, and hypertension

Frontiers in physiology, 2012-01, Vol.3, p.341-341

Drummond, Heather A

2012

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Altered myogenic vasoconstriction and regulation of whole kidney blood flow in the ASIC2 knockout mouse

American journal of physiology. Renal physiology, 2015-02, Vol.308 (4), p.F339-F348

2015

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Is there a role of proinflammatory cytokines on degenerin‐mediated cerebrovascular function in preeclampsia?

Physiological reports, 2022-07, Vol.10 (13), p.e15376-n/a

2022

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Role of PTP1B in POMC neurons during chronic high-fat diet: sex differences in regulation of liver lipids and glucose tolerance

American journal of physiology. Regulatory, integrative and comparative physiology, 2018-03, Vol.314 (3), p.R478-R488

2018

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Impaired myogenic constriction of the renal afferent arteriole in a mouse model of reduced βENaC expression

American journal of physiology. Renal physiology, 2012-06, Vol.302 (11), p.F1486-F1493

2012

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Luminal ANG II is internalized as a complex with AT1R/AT2R heterodimers to target endoplasmic reticulum in LLC-PK1 cells

American journal of physiology. Renal physiology, 2017-08, Vol.313 (2), p.F440-F449

2017

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Targeting Heme Oxygenase-1 in Cardiovascular and Kidney Disease

Antioxidants, 2019-06, Vol.8 (6), p.181

2019

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Vascular ENaC proteins are required for renal myogenic constriction

American journal of physiology. Renal physiology, 2005-10, Vol.289 (4), p.F891-F901

2005

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What Evolutionary Evidence Implies About the Identity of the Mechanoelectrical Couplers in Vascular Smooth Muscle Cells

βENaC and ASIC2 associate in VSMCs to mediate pressure-induced constriction in the renal afferent arteriole

Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3β Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) α

Expression of Exogenous Epithelial Sodium Channel Beta Subunit in the Mouse Middle Cerebral Artery Increases Pressure-Induced Constriction

Pressure-induced constriction of the middle cerebral artery is abolished in TrpC6 knockout mice

Epithelial Sodium Channels in Monocyte‐Macrophage Migration and Regulation by Pro‐inflammatory Cytokines TNFα and IFNγ

Epithelial sodium channels in macrophage migration and polarization: role of proinflammatory cytokines TNFα and IFNγ

Placental ischemia-induced increases in brain water content and cerebrovascular permeability: role of TNF-α

Reduced uterine perfusion pressure induces hypertension in the pregnant mouse

The Ion Channel ASIC2 Is Required for Baroreceptor and Autonomic Control of the Circulation

Interleukin-17 Reduces βENaC via MAPK Signaling in Vascular Smooth Muscle Cells

Tumor necrosis factor-α impairs cerebral blood flow in pregnant rats: role of vascular β-epithelial Na + channel

Bone marrow monocytes and macrophages from mice lacking βENaC and ASIC2 have a reduced chemotactic migration response and polarization

Tumor Necrosis Factor-α Antagonist Etanercept Decreases Blood Pressure and Protects the Kidney in a Mouse Model of Systemic Lupus Erythematosus

CD133+ melanoma subpopulation acquired resistance to caffeic acid phenethyl ester-induced apoptosis is attributed to the elevated expression of ABCB5: Significance for melanoma treatment

A New Trick for an Old Dogma: ENaC Proteins as Mechanotransducers in Vascular Smooth Muscle

Role of carbon monoxide in kidney function: is a little carbon monoxide good for the kidney?

βENaC is a molecular component of a VSMC mechanotransducer that contributes to renal blood flow regulation, protection from renal injury, and hypertension

Altered myogenic vasoconstriction and regulation of whole kidney blood flow in the ASIC2 knockout mouse

Is there a role of proinflammatory cytokines on degenerin‐mediated cerebrovascular function in preeclampsia?

Role of PTP1B in POMC neurons during chronic high-fat diet: sex differences in regulation of liver lipids and glucose tolerance

Impaired myogenic constriction of the renal afferent arteriole in a mouse model of reduced βENaC expression

Luminal ANG II is internalized as a complex with AT1R/AT2R heterodimers to target endoplasmic reticulum in LLC-PK1 cells

Targeting Heme Oxygenase-1 in Cardiovascular and Kidney Disease

Vascular ENaC proteins are required for renal myogenic constriction

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