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Identification of Multiple 5‑HT4 Partial Agonist Clinical Candidates for the Treatment of Alzheimer’s Disease

Journal of medicinal chemistry, 2012-11, Vol.55 (21), p.9240-9254

2012

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Robust changes in expression of brain-derived neurotrophic factor (BDNF) mRNA and protein across the brain do not translate to detectable changes in BDNF levels in CSF or plasma

Biomarkers, 2012-09, Vol.17 (6), p.524-531

2012

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Discovery of a series of 2-(1H-pyrazol-1-yl)pyridines as ALK5 inhibitors with potential utility in the prevention of dermal scarring

Bioorganic & medicinal chemistry letters, 2012-05, Vol.22 (10), p.3392-3397

2012

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Identification of Multiple 5-HT 4 Partial Agonist Clinical Candidates for the Treatment of Alzheimer’s Disease

Journal of medicinal chemistry, 2012-11, Vol.55 (21), p.9240-9254

2012

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Age‐related differences in lean mass, protein synthesis and skeletal muscle markers of proteolysis after bed rest and exercise rehabilitation

The Journal of physiology, 2015-09, Vol.593 (18), p.4259-4273

2015

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Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis

Skeletal muscle, 2011-03, Vol.1 (1), p.11-11, Article 11

2011

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Spontaneous exciton dissociation enables spin state interconversion in delayed fluorescence organic semiconductors

Nature communications, 2021-11, Vol.12 (1), p.6640-6640, Article 6640

2021

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Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women

Experimental gerontology, 2015-05, Vol.65, p.1-7

2015

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Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults

American journal of physiology: endocrinology and metabolism, 2012-05, Vol.302 (9), p.E1113-E1122

2012

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Skeletal muscle autophagy and protein breakdown following resistance exercise are similar in younger and older adults

The journals of gerontology. Series A, Biological sciences and medical sciences, 2013-05, Vol.68 (5), p.599-607

2013

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Leucine-Enriched Amino Acid Ingestion after Resistance Exercise Prolongs Myofibrillar Protein Synthesis and Amino Acid Transporter Expression in Older Men

The Journal of nutrition, 2014-11, Vol.144 (11), p.1694-1702

2014

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Aging and microRNA expression in human skeletal muscle: a microarray and bioinformatics analysis

Physiological genomics, 2011-05, Vol.43 (10), p.595-603

2011

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Skeletal muscle-specific inducible AMPKα1/α2 knockout mice develop muscle weakness, glycogen depletion, and fibrosis that persists during disuse atrophy

American journal of physiology: endocrinology and metabolism, 2024-01, Vol.326 (1), p.E50

2024

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Treadmill training does not enhance skeletal muscle recovery following disuse atrophy in older male mice

Frontiers in physiology, 2023-10, Vol.14, p.1263500

2023

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Macrophage immunomodulation accelerates skeletal muscle functional recovery in aged mice following disuse atrophy

Journal of applied physiology (1985), 2022-10, Vol.133 (4), p.919-931

2022

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Short-term bed rest increases TLR4 and IL-6 expression in skeletal muscle of older adults

American journal of physiology. Regulatory, integrative and comparative physiology, 2013-08, Vol.305 (3), p.R216-R223

2013

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Dietary delivery of glycomacropeptide within the whey protein matrix is not effective in mitigating tissue ceramide deposition and obesity in mice fed a high-fat diet

Journal of dairy science, 2024-02, Vol.107 (2), p.669-682

2024

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Global deletion of CCL2 has adverse impacts on recovery of skeletal muscle fiber size and function and is muscle specific

Journal of applied physiology (1985), 2023-04, Vol.134 (4), p.923-932

2023

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Resistance exercise increases leg muscle protein synthesis and mTOR signalling independent of sex

Acta Physiologica, 2010-05, Vol.199 (1), p.71-81

2010

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Stem cell secretome treatment improves whole‐body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice

Aging cell, 2024-06, Vol.23 (6), p.e14144-n/a

2024

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Aging differentially affects human skeletal muscle amino acid transporter expression when essential amino acids are ingested after exercise

Clinical nutrition (Edinburgh, Scotland), 2013-04, Vol.32 (2), p.273-280

2013

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Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise

Journal of applied physiology (1985), 2011-07, Vol.111 (1), p.135-142

2011

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Palmitate-Induced Inflammation and Myotube Atrophy in C2C12 Cells Are Prevented by the Whey Bioactive Peptide, Glycomacropeptide

The Journal of nutrition, 2023-10, Vol.153 (10), p.2915-2928

2023

Volltextzugriff (PDF)

Safety and Efficacy of Fedratinib in Patients With Primary or Secondary Myelofibrosis: A Randomized Clinical Trial

JAMA oncology, 2015-08, Vol.1 (5), p.643

2015

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Identification of Multiple 5‑HT4 Partial Agonist Clinical Candidates for the Treatment of Alzheimer’s Disease

Rational Design and Synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications

Robust changes in expression of brain-derived neurotrophic factor (BDNF) mRNA and protein across the brain do not translate to detectable changes in BDNF levels in CSF or plasma

Discovery of a series of 2-(1H-pyrazol-1-yl)pyridines as ALK5 inhibitors with potential utility in the prevention of dermal scarring

Identification of Multiple 5-HT 4 Partial Agonist Clinical Candidates for the Treatment of Alzheimer’s Disease

Age‐related differences in lean mass, protein synthesis and skeletal muscle markers of proteolysis after bed rest and exercise rehabilitation

Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis

Spontaneous exciton dissociation enables spin state interconversion in delayed fluorescence organic semiconductors

Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women

Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults

Skeletal muscle autophagy and protein breakdown following resistance exercise are similar in younger and older adults

Leucine-Enriched Amino Acid Ingestion after Resistance Exercise Prolongs Myofibrillar Protein Synthesis and Amino Acid Transporter Expression in Older Men

Aging and microRNA expression in human skeletal muscle: a microarray and bioinformatics analysis

Skeletal muscle-specific inducible AMPKα1/α2 knockout mice develop muscle weakness, glycogen depletion, and fibrosis that persists during disuse atrophy

Treadmill training does not enhance skeletal muscle recovery following disuse atrophy in older male mice

Macrophage immunomodulation accelerates skeletal muscle functional recovery in aged mice following disuse atrophy

Short-term bed rest increases TLR4 and IL-6 expression in skeletal muscle of older adults

Dietary delivery of glycomacropeptide within the whey protein matrix is not effective in mitigating tissue ceramide deposition and obesity in mice fed a high-fat diet

Global deletion of CCL2 has adverse impacts on recovery of skeletal muscle fiber size and function and is muscle specific

Resistance exercise increases leg muscle protein synthesis and mTOR signalling independent of sex

Stem cell secretome treatment improves whole‐body metabolism, reduces adiposity, and promotes skeletal muscle function in aged mice

Aging differentially affects human skeletal muscle amino acid transporter expression when essential amino acids are ingested after exercise

Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise

Palmitate-Induced Inflammation and Myotube Atrophy in C2C12 Cells Are Prevented by the Whey Bioactive Peptide, Glycomacropeptide

Safety and Efficacy of Fedratinib in Patients With Primary or Secondary Myelofibrosis: A Randomized Clinical Trial

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