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Plasma proteome of growing tumors

Scientific reports, 2023-07, Vol.13 (1), p.12195-12195, Article 12195

2023

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The effect of rifampicin, a prototypical CYP3A4 inducer, on erlotinib pharmacokinetics in healthy subjects

Cancer chemotherapy and pharmacology, 2014-03, Vol.73 (3), p.613-621

2014

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Fit for the Eye: Aptamers in Ocular Disorders

Nucleic acid therapeutics, 2016-06, Vol.26 (3), p.127-146

2016

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The Inhibitory Effects of a Factor B–Binding DNA Aptamer Family Supersede the Gain of Function of Factor B Variants Associated with Atypical Hemolytic Uremic Syndrome

The Journal of immunology (1950), 2024-10

2024

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Inhibition of the Complement Alternative Pathway by Chemically Modified DNA Aptamers That Bind with Picomolar Affinity to Factor B

The Journal of immunology (1950), 2021-02, Vol.206 (4), p.861-873

2021

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Crossing the Halfway Point: Aptamer-Based, Highly Multiplexed Assay for the Assessment of the Proteome

Journal of proteome research, 2024-11, Vol.23 (11), p.4771-4788

2024

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Phase I, Pharmacokinetic and Biological Correlative Study of OSI-7904L, a Novel Liposomal Thymidylate Synthase Inhibitor, and Cisplatin in Patients with Solid Tumors

Clinical cancer research, 2008-12, Vol.14 (23), p.7947-7955

2008

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Chemically Modified Interleukin-6 Aptamer Inhibits Development of Collagen-Induced Arthritis in Cynomolgus Monkeys

Nucleic acid therapeutics, 2016-02, Vol.26 (1), p.10-19

2016

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Pharmacokinetic Properties of DNA Aptamers with Base Modifications

Nucleic acid therapeutics, 2017-12, Vol.27 (6), p.345-353

2017

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Proteomic Profiles in Advanced Age-Related Macular Degeneration Using an Aptamer-Based Proteomic Technology

Translational vision science & technology, 2019-01, Vol.8 (1), p.14-14

2019

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Pharmacokinetics, safety, and efficacy of a liposome encapsulated thymidylate synthase inhibitor, OSI-7904L [(S)-2-[5-[(1,2-dihydro-3-methyl-1-oxobenzo[f]quinazolin-9-yl)methyl]amino-1-oxo-2-isoindolynl]-glutaric acid] in mice

The Journal of pharmacology and experimental therapeutics, 2004-06, Vol.309 (3), p.894-902

2004

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A nonclinical safety and pharmacokinetic evaluation of N6022: A first-in-class S-nitrosoglutathione reductase inhibitor for the treatment of asthma

Regulatory toxicology and pharmacology, 2012-02, Vol.62 (1), p.115-124

2012

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A Phase I Study of a New Nucleoside Analogue, OSI-7836, Using Two Administration Schedules in Patients with Advanced Solid Malignancies

Clinical cancer research, 2006-05, Vol.12 (9), p.2841-2848

2006

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An enzyme-linked oligonucleotide assay

Nature biotechnology, 1996-08, Vol.14 (8), p.1021-1025

1996

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Reduced Fertility in Mice Deficient for the POU Protein Sperm-1

Proceedings of the National Academy of Sciences - PNAS, 1997-07, Vol.94 (14), p.7555-7560

1997

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POU-domain proteins: structure and function of developmental regulators

Current opinion in cell biology, 1993-06, Vol.5 (3), p.488-498

1993

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Pituitary ontogeny of the Snell dwarf mouse reveals Pit-1-independent and Pit-1-dependent origins of the thyrotrope

Development (Cambridge), 1994-03, Vol.120 (3), p.515-522

1994

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Safety Assessment of 4′-Thio-β-d-Arabinofuranosylcytosine in the Beagle Dog Suggests a Drug-Induced Centrally Mediated Effect on the Hypothalamic-Pituitary-Adrenal Axis

International journal of toxicology, 2006-03, Vol.25 (2), p.119-126

2006

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Regulation of JC Virus by the POU-Domain Transcription Factor Tst-1: Implications for Progressive Multifocal Leukoencephalopathy

Proceedings of the National Academy of Sciences - PNAS, 1993-05, Vol.90 (10), p.4743-4747

1993

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Preclinical and phase 1A clinical evaluation of an anti-VEGF pegylated aptamer (EYE001) for the treatment of exudative age-related macular degeneration

Retina (Philadelphia, Pa.), 2002-04, Vol.22 (2), p.143-152

2002

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Pharmacokinetics and safety of an anti-vascular endothelial growth factor aptamer (NX1838) following injection into the vitreous humor of rhesus monkeys

Pharmaceutical research, 2000-12, Vol.17 (12), p.1503-1510

2000

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S-nitrosoglutathione reductase inhibitors for the prevention and treatment of experimental colitis: P-251

Inflammatory bowel diseases, 2011-12, Vol.17, p.S86

2011

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Aptamer affinity chromatography:: combinatorial chemistry applied to protein purification

Journal of chromatography. B, Biomedical sciences and applications, 1999-08, Vol.731 (2), p.275-284

1999

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Detection and plasma pharmacokinetics of an anti-vascular endothelial growth factor oligonucleotide-aptamer (NX1838) in rhesus monkeys

Journal of chromatography. B, Biomedical sciences and applications, 1999-09, Vol.732 (1), p.203-212

1999

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TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins

Genes & development, 1991-10, Vol.5 (10), p.1739-1753

1991

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Plasma proteome of growing tumors

The effect of rifampicin, a prototypical CYP3A4 inducer, on erlotinib pharmacokinetics in healthy subjects

Fit for the Eye: Aptamers in Ocular Disorders

The Inhibitory Effects of a Factor B–Binding DNA Aptamer Family Supersede the Gain of Function of Factor B Variants Associated with Atypical Hemolytic Uremic Syndrome

Inhibition of the Complement Alternative Pathway by Chemically Modified DNA Aptamers That Bind with Picomolar Affinity to Factor B

Crossing the Halfway Point: Aptamer-Based, Highly Multiplexed Assay for the Assessment of the Proteome

Phase I, Pharmacokinetic and Biological Correlative Study of OSI-7904L, a Novel Liposomal Thymidylate Synthase Inhibitor, and Cisplatin in Patients with Solid Tumors

Chemically Modified Interleukin-6 Aptamer Inhibits Development of Collagen-Induced Arthritis in Cynomolgus Monkeys

Pharmacokinetic Properties of DNA Aptamers with Base Modifications

Proteomic Profiles in Advanced Age-Related Macular Degeneration Using an Aptamer-Based Proteomic Technology

Pharmacokinetics, safety, and efficacy of a liposome encapsulated thymidylate synthase inhibitor, OSI-7904L [(S)-2-[5-[(1,2-dihydro-3-methyl-1-oxobenzo[f]quinazolin-9-yl)methyl]amino-1-oxo-2-isoindolynl]-glutaric acid] in mice

A nonclinical safety and pharmacokinetic evaluation of N6022: A first-in-class S-nitrosoglutathione reductase inhibitor for the treatment of asthma

A Phase I Study of a New Nucleoside Analogue, OSI-7836, Using Two Administration Schedules in Patients with Advanced Solid Malignancies

An enzyme-linked oligonucleotide assay

Reduced Fertility in Mice Deficient for the POU Protein Sperm-1

POU-domain proteins: structure and function of developmental regulators

Pituitary ontogeny of the Snell dwarf mouse reveals Pit-1-independent and Pit-1-dependent origins of the thyrotrope

Safety Assessment of 4′-Thio-β-d-Arabinofuranosylcytosine in the Beagle Dog Suggests a Drug-Induced Centrally Mediated Effect on the Hypothalamic-Pituitary-Adrenal Axis

Regulation of JC Virus by the POU-Domain Transcription Factor Tst-1: Implications for Progressive Multifocal Leukoencephalopathy

Preclinical and phase 1A clinical evaluation of an anti-VEGF pegylated aptamer (EYE001) for the treatment of exudative age-related macular degeneration

Pharmacokinetics and safety of an anti-vascular endothelial growth factor aptamer (NX1838) following injection into the vitreous humor of rhesus monkeys

S-nitrosoglutathione reductase inhibitors for the prevention and treatment of experimental colitis: P-251

Aptamer affinity chromatography:: combinatorial chemistry applied to protein purification

Detection and plasma pharmacokinetics of an anti-vascular endothelial growth factor oligonucleotide-aptamer (NX1838) in rhesus monkeys

TEF, a transcription factor expressed specifically in the anterior pituitary during embryogenesis, defines a new class of leucine zipper proteins

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