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Total synthesis of (.+-.)-calanolide A, a non-nucleoside inhibitor of HIV-1 reverse transcriptase

Journal of organic chemistry, 1993-10, Vol.58 (21), p.5605-5606

1993

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Purification and biochemical characterization of recombinant simian immunodeficiency virus protease and comparison to human immunodeficiency virus type 1 protease

Biochemistry (Easton), 1991-08, Vol.30 (34), p.8424-8434

1991

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Synthetic studies on arene-olefin cycloadditions. 4. Total synthesis of (.+-.)-modhephene

Journal of the American Chemical Society, 1982-10, Vol.104 (21), p.5805-5807

1982

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Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, x-ray crystallography, and infected T-cell assays

Biochemistry (Easton), 1992-07, Vol.31 (29), p.6646-6659

1992

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Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues

Nature (London), 1990-01, Vol.343 (6253), p.90-92

1990

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A symmetric inhibitor binds HIV-1 protease asymmetrically

Biochemistry (Easton), 1993, Vol.32 (3), p.937-947

1993

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Synthetic studies on arene-olefin cycloadditions - V. total synthesis of (±)-isoiridomyrmecin

Tetrahedron letters, 1983, Vol.24 (42), p.4543-4546

1983

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The Pseudocalanolides: Structure Revision of Calanolides C and D

Journal of natural products (Washington, D.C.), 1995-06, Vol.58 (6), p.916-920

1995

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Substrate-based inhibitors of HIV-1 protease

Perspectives in drug discovery and design, 1993-08, Vol.1 (1), p.85-108

1993

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Proteolysis of an active site peptide of lactate dehydrogenase by human immunodeficiency virus type 1 protease

Biochemistry (Easton), 1992-10, Vol.31 (42), p.10153-10168

1992

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Inhibition of Human Immunodeficiency Virus 1 Protease in vitro: Rational Design of Substrate Analogue Inhibitors

Proceedings of the National Academy of Sciences - PNAS, 1989-12, Vol.86 (24), p.9752-9756

1989

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Sequence-Specific Cleavage of Single-Stranded DNA: Oligodeoxynucleotide-EDTA· Fe(II)

Proceedings of the National Academy of Sciences - PNAS, 1985-02, Vol.82 (4), p.968-972

1985

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Human Immunodeficiency Virus 1 Protease Expressed in Escherichia coli Behaves as a Dimeric Aspartic Protease

Proceedings of the National Academy of Sciences - PNAS, 1989-03, Vol.86 (6), p.1841-1845

1989

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Peptide substrates and inhibitors of the HIV-1 protease

Biochemical and biophysical research communications, 1989-03, Vol.159 (2), p.420-425

1989

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Synthetic studies on arene-olefin cycloadditions. ii. total synthesis of (±)-isocomene

Tetrahedron, 1981, Vol.37 (25), p.4445-4450

1981

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Inhibition of human immunodeficiency virus-1 protease by a C2-symmetric phosphinate. Synthesis and crystallographic analysis

Biochemistry (Easton), 1993-08, Vol.32 (31), p.7972-7980

1993

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An Orally Bioavailable HIV-1 Protease Inhibitor Containing an Imidazole-Derived Peptide Bond Replacement: Crystallographic and Pharmacokinetic Analysis

Biochemistry (Easton), 1994-10, Vol.33 (39), p.11671-11677

1994

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Effect of retroviral proteinase inhibitors on Mason-Pfizer monkey virus maturation and transmembrane glycoprotein cleavage

Journal of Virology, 1992-07, Vol.66 (7), p.4220-4227

1992

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Synthesis of C2-symmetric and pseudosymmetric HIV-1 protease inhibitors from D-arabitol

Bioorganic & medicinal chemistry letters, 1991-01, Vol.1 (4), p.219-222

1991

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α,α-Difluoroketone inhibitors of HMG CoA reductase

Tetrahedron letters, 1988, Vol.29 (52), p.6885-6888

1988

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HIV-1 Protease as a Potential Target for Anti-AIDS Therapy

Annals of the New York Academy of Sciences, 1990, Vol.616 (1), p.41-53

1990

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Nonpeptide HIV protease inhibitors designed to replace a bound water

Bioorganic & medicinal chemistry letters, 1993-12, Vol.3 (12), p.2717-2722

1993

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Potent inhibition of HIV type 1 infection of mononuclear phagocytes by synthetic peptide analogs of HIV type 1 protease substrates

AIDS research and human retroviruses, 1996-06, Vol.12 (9), p.777-782

1996

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Synthesis of C 2-symmetric and pseudosymmetric HIV-1 protease inhibitors from D-arabitol

Bioorganic & medicinal chemistry letters, 1991, Vol.1 (4), p.219-222

1991

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Effects of SKF 108922, an HIV-1 protease inhibitor, on retrovirus replication in mice

Antiviral research, 1996-03, Vol.29 (2), p.175-186

1996

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Total synthesis of (.+-.)-calanolide A, a non-nucleoside inhibitor of HIV-1 reverse transcriptase

Purification and biochemical characterization of recombinant simian immunodeficiency virus protease and comparison to human immunodeficiency virus type 1 protease

Synthetic studies on arene-olefin cycloadditions. 4. Total synthesis of (.+-.)-modhephene

Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, x-ray crystallography, and infected T-cell assays

Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues

A symmetric inhibitor binds HIV-1 protease asymmetrically

Synthetic studies on arene-olefin cycloadditions - V. total synthesis of (±)-isoiridomyrmecin

The Pseudocalanolides: Structure Revision of Calanolides C and D

Substrate-based inhibitors of HIV-1 protease

Proteolysis of an active site peptide of lactate dehydrogenase by human immunodeficiency virus type 1 protease

Inhibition of Human Immunodeficiency Virus 1 Protease in vitro: Rational Design of Substrate Analogue Inhibitors

Sequence-Specific Cleavage of Single-Stranded DNA: Oligodeoxynucleotide-EDTA· Fe(II)

Human Immunodeficiency Virus 1 Protease Expressed in Escherichia coli Behaves as a Dimeric Aspartic Protease

Peptide substrates and inhibitors of the HIV-1 protease

Synthetic studies on arene-olefin cycloadditions. ii. total synthesis of (±)-isocomene

Inhibition of human immunodeficiency virus-1 protease by a C2-symmetric phosphinate. Synthesis and crystallographic analysis

An Orally Bioavailable HIV-1 Protease Inhibitor Containing an Imidazole-Derived Peptide Bond Replacement: Crystallographic and Pharmacokinetic Analysis

Effect of retroviral proteinase inhibitors on Mason-Pfizer monkey virus maturation and transmembrane glycoprotein cleavage

Synthesis of C2-symmetric and pseudosymmetric HIV-1 protease inhibitors from D-arabitol

α,α-Difluoroketone inhibitors of HMG CoA reductase

HIV-1 Protease as a Potential Target for Anti-AIDS Therapy

Nonpeptide HIV protease inhibitors designed to replace a bound water

Potent inhibition of HIV type 1 infection of mononuclear phagocytes by synthetic peptide analogs of HIV type 1 protease substrates

Synthesis of C 2-symmetric and pseudosymmetric HIV-1 protease inhibitors from D-arabitol

Effects of SKF 108922, an HIV-1 protease inhibitor, on retrovirus replication in mice

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