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Continuous manufacturing of pharmaceutical products: A density-insensitive near infrared method for the in-line monitoring of continuous powder streams

International journal of pharmaceutics, 2024-01, Vol.650, p.123699-123699, Article 123699

2024

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Refractive Index Measurement of Pharmaceutical Solids: A Review of Measurement Methods and Pharmaceutical Applications

Journal of pharmaceutical sciences, 2019-11, Vol.108 (11), p.3478-3495

2019

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Influence of powder stream density on near infrared measurements upon scale-up of a simulated continuous process

International journal of pharmaceutics, 2023-10, Vol.645, p.123354-123354, Article 123354

2023

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Method Development and Validation of an Inline Process Analytical Technology Method for Blend Monitoring in the Tablet Feed Frame Using Raman Spectroscopy

Analytical chemistry (Washington), 2018-07, Vol.90 (14), p.8436-8444

2018

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Quality by Design Approach Using Multiple Linear and Logistic Regression Modeling Enables Microemulsion Scale Up

Molecules (Basel, Switzerland), 2019-05, Vol.24 (11), p.2066

2019

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Capacitance spectroscopy enables real‐time monitoring of early cell death in mammalian cell culture

Biotechnology journal, 2023-03, Vol.18 (3), p.e2200231-n/a

2023

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Development of calibration-free/minimal calibration wavelength selection for iterative optimization technology algorithms toward process analytical technology application

International journal of pharmaceutics, 2022-02, Vol.614, p.121463-121463, Article 121463

2022

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Prediction of Dissolution Profiles From Process Parameters, Formulation, and Spectroscopic Measurements

Journal of pharmaceutical sciences, 2019-06, Vol.108 (6), p.2119-2127

2019

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In-line monitoring and optimization of powder flow in a simulated continuous process using transmission near infrared spectroscopy

International journal of pharmaceutics, 2017-06, Vol.526 (1-2), p.199-208

2017

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NIR spectroscopic methods for monitoring blend potency in a feed frame - calibration transfer between offline and inline using a continuum regression filter

International journal of pharmaceutics, 2022-02, Vol.614, p.121363-121363, Article 121363

2022

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Development of an In-Line Near-Infrared Method for Blend Content Uniformity Assessment in a Tablet Feed Frame

Applied spectroscopy, 2019-09, Vol.73 (9), p.1028-1040

2019

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NIR Spectroscopy as an Online PAT Tool for a Narrow Therapeutic Index Drug: Toward a Platform Approach Across Lab and Pilot Scales for Development of a Powder Blending Monitoring Method and Endpoint Determination

The AAPS journal, 2022-09, Vol.24 (6), p.103, Article 103

2022

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Method development and validation for pharmaceutical tablets analysis using transmission Raman spectroscopy

International journal of pharmaceutics, 2016-02, Vol.498 (1-2), p.318-325

2016

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Multicomponent granular mixing in a Bohle bin Blender-Experiments and simulation

International journal of pharmaceutics, 2020-03, Vol.578, p.119131-119131, Article 119131

2020

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A “Large-N” Content Uniformity Process Analytical Technology (PAT) Method for Phenytoin Sodium Tablets

Journal of pharmaceutical sciences, 2019-01, Vol.108 (1), p.494-505

2019

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Terahertz Time of Flight Spectroscopy as a Coating Thickness Reference Method for Partial Least Squares Near Infrared Spectroscopy Models

Analytical chemistry (Washington), 2020-03, Vol.92 (5), p.3658-3665

2020

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A robust quantitative near infrared modeling approach for blend monitoring

Journal of pharmaceutical and biomedical analysis, 2018-01, Vol.148, p.51-57

2018

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Influence of moisture variation on the performance of Raman spectroscopy in quantitative pharmaceutical analyses

Journal of pharmaceutical and biomedical analysis, 2019-02, Vol.164, p.528-535

2019

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Quality by Design Methodology Applied to Process Optimization and Scale up of Curcumin Nanoemulsions Produced by Catastrophic Phase Inversion

Pharmaceutics, 2021-06, Vol.13 (6), p.880

2021

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Effects and Detection of Raw Material Variability on the Performance of Near-Infrared Calibration Models for Pharmaceutical Products

Journal of pharmaceutical sciences, 2014-02, Vol.103 (2), p.545-556

2014

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A Process Analytical Technology approach to near-infrared process control of pharmaceutical powder blending. Part III: Quantitative near-infrared calibration for prediction of blend homogeneity and characterization of powder mixing kinetics

Journal of pharmaceutical sciences, 2006-02, Vol.95 (2), p.422-434

2006

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Development of a Fluid Bed Granulation Design Space Using Critical Quality Attribute Weighted Tolerance Intervals

Journal of pharmaceutical sciences, 2012-08, Vol.101 (8), p.2917-2929

2012

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Investigation of the Sensitivity of Transmission Raman Spectroscopy for Polymorph Detection in Pharmaceutical Tablets

Applied spectroscopy, 2017-08, Vol.71 (8), p.1856-1867

2017

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Determination of Spatially Resolved Tablet Density and Hardness Using Near-Infrared Chemical Imaging (NIR-CI)

Applied spectroscopy, 2017-08, Vol.71 (8), p.1906-1914

2017

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A Process Analytical Technology approach to near-infrared process control of pharmaceutical powder blending. Part I: D-optimal design for characterization of powder mixing and preliminary spectral data evaluation

Journal of pharmaceutical sciences, 2006-02, Vol.95 (2), p.392-406

2006

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Continuous manufacturing of pharmaceutical products: A density-insensitive near infrared method for the in-line monitoring of continuous powder streams

Refractive Index Measurement of Pharmaceutical Solids: A Review of Measurement Methods and Pharmaceutical Applications

Influence of powder stream density on near infrared measurements upon scale-up of a simulated continuous process

Method Development and Validation of an Inline Process Analytical Technology Method for Blend Monitoring in the Tablet Feed Frame Using Raman Spectroscopy

Quality by Design Approach Using Multiple Linear and Logistic Regression Modeling Enables Microemulsion Scale Up

Capacitance spectroscopy enables real‐time monitoring of early cell death in mammalian cell culture

Development of calibration-free/minimal calibration wavelength selection for iterative optimization technology algorithms toward process analytical technology application

Prediction of Dissolution Profiles From Process Parameters, Formulation, and Spectroscopic Measurements

In-line monitoring and optimization of powder flow in a simulated continuous process using transmission near infrared spectroscopy

NIR spectroscopic methods for monitoring blend potency in a feed frame - calibration transfer between offline and inline using a continuum regression filter

Development of an In-Line Near-Infrared Method for Blend Content Uniformity Assessment in a Tablet Feed Frame

NIR Spectroscopy as an Online PAT Tool for a Narrow Therapeutic Index Drug: Toward a Platform Approach Across Lab and Pilot Scales for Development of a Powder Blending Monitoring Method and Endpoint Determination

Method development and validation for pharmaceutical tablets analysis using transmission Raman spectroscopy

Multicomponent granular mixing in a Bohle bin Blender-Experiments and simulation

A “Large-N” Content Uniformity Process Analytical Technology (PAT) Method for Phenytoin Sodium Tablets

Terahertz Time of Flight Spectroscopy as a Coating Thickness Reference Method for Partial Least Squares Near Infrared Spectroscopy Models

A robust quantitative near infrared modeling approach for blend monitoring

Influence of moisture variation on the performance of Raman spectroscopy in quantitative pharmaceutical analyses

Quality by Design Methodology Applied to Process Optimization and Scale up of Curcumin Nanoemulsions Produced by Catastrophic Phase Inversion

Effects and Detection of Raw Material Variability on the Performance of Near-Infrared Calibration Models for Pharmaceutical Products

A Process Analytical Technology approach to near-infrared process control of pharmaceutical powder blending. Part III: Quantitative near-infrared calibration for prediction of blend homogeneity and characterization of powder mixing kinetics

Development of a Fluid Bed Granulation Design Space Using Critical Quality Attribute Weighted Tolerance Intervals

Investigation of the Sensitivity of Transmission Raman Spectroscopy for Polymorph Detection in Pharmaceutical Tablets

Determination of Spatially Resolved Tablet Density and Hardness Using Near-Infrared Chemical Imaging (NIR-CI)

A Process Analytical Technology approach to near-infrared process control of pharmaceutical powder blending. Part I: D-optimal design for characterization of powder mixing and preliminary spectral data evaluation

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