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Structural basis of adenylyl cyclase 9 activation

Nature communications, 2022-02, Vol.13 (1), p.1045-1045, Article 1045

2022

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Rapid selection of high-affinity binders using ribosome display

Methods in molecular biology (Clifton, N.J.), 2012-01, Vol.805, p.261

2012

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Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system

PLoS pathogens, 2023-05, Vol.19 (5), p.e1011368-e1011368

2023

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Structure of a kinesin-tubulin complex and implications for kinesin motility

Nature structural & molecular biology, 2013-08, Vol.20 (8), p.1001-1007

2013

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Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins

Nature communications, 2020-10, Vol.11 (1), p.5199-5199, Article 5199

2020

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Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control

Nature communications, 2018-01, Vol.9 (1), p.450-16, Article 450

2018

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A DARPin-based molecular toolset to probe gephyrin and inhibitory synapse biology

eLife, 2022-10, Vol.11

2022

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designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (30), p.12011-12016

2012

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Nuclear myosin VI maintains replication fork stability

Nature communications, 2023-06, Vol.14 (1), p.3787-3787, Article 3787

2023

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Disrupting the HDAC6-ubiquitin interaction impairs infection by influenza and Zika virus and cellular stress pathways

Cell reports (Cambridge), 2022-04, Vol.39 (4), p.110736-110736, Article 110736

2022

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DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma

Cell death & disease, 2023-10, Vol.14 (10), p.674-674, Article 674

2023

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The RGD-binding integrins αvβ6 and αvβ8 are receptors for mouse adenovirus-1 and -3 infection

PLoS pathogens, 2021-12, Vol.17 (12), p.e1010083

2021

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Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (10), p.E869-E877

2013

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Conformation-Dependent Recognition of HIV gp120 by Designed Ankyrin Repeat Proteins Provides Access to Novel HIV Entry Inhibitors

Journal of Virology, 2013-05, Vol.87 (10), p.5868-5881

2013

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Specific cleavage of agrin by neurotrypsin, a synaptic protease linked to mental retardation

The FASEB journal, 2007-11, Vol.21 (13), p.3468-3478

2007

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A Library-Based Screening Strategy for the Identification of DARPins as Ligands for Receptor-Targeted AAV and Lentiviral Vectors

Molecular therapy. Methods & clinical development, 2018-09, Vol.10, p.128-143

2018

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Positive and Negative Regulation of Endogenous Genes by Designed Transcription Factors

Proceedings of the National Academy of Sciences - PNAS, 2000-02, Vol.97 (4), p.1495-1500

2000

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Toward Controlling Gene Expression at Will: Selection and Design of Zinc Finger Domains Recognizing Each of the 5′-GNN-3′DNA Target Sequences

Proceedings of the National Academy of Sciences - PNAS, 1999-03, Vol.96 (6), p.2758-2763

1999

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Toward Controlling Gene Expression at Will: Specific Regulation of the erbB-2/HER-2 Promoter by using Polydactyl Zinc Finger Proteins Constructed from Modular Building Blocks

Proceedings of the National Academy of Sciences - PNAS, 1998-12, Vol.95 (25), p.14628-14633

1998

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A Library-Based Screening Strategy for the Identification of DARPins as Ligands for Receptor-Targeted AAV and Lentiviral Vectors

Molecular therapy. Methods & clinical development, 2021-06, Vol.21, p.728-728

2021

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Assessing immunogenicity barriers of the HIV-1 envelope trimer

npj vaccines, 2023-09, Vol.8 (1), p.148-148, Article 148

2023

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Evaluation of a Modular Strategy for the Construction of Novel Polydactyl Zinc Finger DNA-Binding Proteins

Biochemistry (Easton), 2003-02, Vol.42 (7), p.2137-2148

2003

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Chemically Regulated Zinc Finger Transcription Factors

The Journal of biological chemistry, 2000-10, Vol.275 (42), p.32617-32627

2000

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Molecular imaging of PSA using DARPin scaffolds

Nuclear medicine and biology, 2022-05, Vol.108-109, p.S190-S191

2022

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P-258 - Molecular imaging of PSA using DARPin scaffolds

Nuclear medicine and biology, 2022-05, Vol.108-109, p.S190-S191

2022

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Structural basis of adenylyl cyclase 9 activation

Rapid selection of high-affinity binders using ribosome display

Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system

Structure of a kinesin-tubulin complex and implications for kinesin motility

Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins

Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control

A DARPin-based molecular toolset to probe gephyrin and inhibitory synapse biology

designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end

Nuclear myosin VI maintains replication fork stability

Disrupting the HDAC6-ubiquitin interaction impairs infection by influenza and Zika virus and cellular stress pathways

DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma

The RGD-binding integrins αvβ6 and αvβ8 are receptors for mouse adenovirus-1 and -3 infection

Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters

Conformation-Dependent Recognition of HIV gp120 by Designed Ankyrin Repeat Proteins Provides Access to Novel HIV Entry Inhibitors

Specific cleavage of agrin by neurotrypsin, a synaptic protease linked to mental retardation

A Library-Based Screening Strategy for the Identification of DARPins as Ligands for Receptor-Targeted AAV and Lentiviral Vectors

Positive and Negative Regulation of Endogenous Genes by Designed Transcription Factors

Toward Controlling Gene Expression at Will: Selection and Design of Zinc Finger Domains Recognizing Each of the 5′-GNN-3′DNA Target Sequences

Toward Controlling Gene Expression at Will: Specific Regulation of the erbB-2/HER-2 Promoter by using Polydactyl Zinc Finger Proteins Constructed from Modular Building Blocks

A Library-Based Screening Strategy for the Identification of DARPins as Ligands for Receptor-Targeted AAV and Lentiviral Vectors

Assessing immunogenicity barriers of the HIV-1 envelope trimer

Evaluation of a Modular Strategy for the Construction of Novel Polydactyl Zinc Finger DNA-Binding Proteins

Chemically Regulated Zinc Finger Transcription Factors

Molecular imaging of PSA using DARPin scaffolds

P-258 - Molecular imaging of PSA using DARPin scaffolds

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