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Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors

PloS one, 2019-07, Vol.14 (7), p.e0218897

2019

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High-Throughput Screening to Identify Inhibitors of the Type I Interferon–Major Histocompatibility Complex Class I Pathway in Skeletal Muscle

ACS chemical biology, 2020-07, Vol.15 (7), p.1974-1986

2020

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In vivo quantitative high-throughput screening for drug discovery and comparative toxicology

Disease models & mechanisms, 2023-03, Vol.16 (3)

2023

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High-throughput screening identifies cell cycle-associated signaling cascades that regulate a multienzyme glucosome assembly in human cells

PloS one, 2023-08, Vol.18 (8), p.e0289707-e0289707

2023

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Structure–activity relationship of ipglycermide binding to phosphoglycerate mutases

The Journal of biological chemistry, 2021-01, Vol.296 (C), p.100628-100628, Article 100628

2021

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First person – Patricia Dranchak

Disease models & mechanisms, 2023-03, Vol.16 (3)

2023

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Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases

Nature communications, 2017-04, Vol.8 (1), p.14932-14932, Article 14932

2017

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qHTSWaterfall: 3-dimensional visualization software for quantitative high-throughput screening (qHTS) data

Journal of cheminformatics, 2023-03, Vol.15 (1), p.39-39, Article 39

2023

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A fission yeast platform for heterologous expression of mammalian adenylyl cyclases and high throughput screening

Cellular signalling, 2019-08, Vol.60, p.114-121

2019

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mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft

BMC genomics, 2008-11, Vol.9 (1), p.521-521, Article 521

2008

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Synthesis and anticancer properties of water-soluble zinc ionophores

Cancer research (Chicago, Ill.), 2008-07, Vol.68 (13), p.5318-5325

2008

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Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays

PloS one, 2013-03, Vol.8 (3), p.e57888-e57888

2013

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Nonsense suppressor therapies rescue peroxisome lipid metabolism and assembly in cells from patients with specific PEX gene mutations

Journal of cellular biochemistry, 2011-05, Vol.112 (5), p.1250-1258

2011

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Genome-Edited Coincidence and PMP22-HiBiT Fusion Reporter Cell Lines Enable an Artifact-Suppressive Quantitative High-Throughput Screening Strategy for PMP22 Gene-Dosage Disorder Drug Discovery

ACS pharmacology & translational science, 2021-08, Vol.4 (4), p.1422-1436

2021

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Diverse captive non-human primates with phytanic acid-deficient diets rich in plant products have substantial phytanic acid levels in their red blood cells

Lipids in health and disease, 2013-02, Vol.12 (1), p.10-10, Article 10

2013

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The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesis

Stem cell research & therapy, 2012-10, Vol.3 (5), p.39-39, Article 39

2012

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Inhibition of natriuretic peptide receptor 1 reduces itch in mice

Science translational medicine, 2019-07, Vol.11 (500)

2019

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Protection Against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine

Science (American Association for the Advancement of Science), 2013-09, Vol.341 (6152), p.1359-1365

2013

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Development of a dopaminergic neurodegeneration assay using laser cytometry of Caenorhabditis elegans models of Parkinson's disease

The FASEB journal, 2021-05, Vol.35 (S1), p.n/a, Article fasebj.2021.35.S1.02267

2021

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A Macrocyclic Peptide Library with a Structurally Constrained Cyclopropane‐containing Building Block Leads to Thiol‐independent Inhibitors of Phosphoglycerate Mutase

Chemistry, an Asian journal, 2020-09, Vol.15 (17), p.2631-2636

2020

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Inheritance of recurrent exertional rhabdomyolysis in thoroughbreds

Journal of the American Veterinary Medical Association, 2005-09, Vol.227 (5), p.762-767

2005

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Abstract 19: Targeting Delta133p53 isoform with small-molecule compounds to modulate cellular senescence

Clinical cancer research, 2020-06, Vol.26 (12_Supplement_1), p.19-19

2020

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Development of a dopaminergic neurodegeneration assay using laser cytometry of Caenorhabditis elegans models of Parkinson’s disease

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Exclusion of linkage of the RYR1, CACNA1S, and ATP2A1 genes to recurrent exertional rhabdomyolysis in Thoroughbreds

American journal of veterinary research, 2006-08, Vol.67 (8), p.1395-1400

2006

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Methotrexate-based PROTACs as DHFR-specific chemical probes

Cell chemical biology, 2024-02, Vol.31 (2), p.221-233.e14

2024

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Quantitative high-throughput screening assays for the discovery and development of SIRPα-CD47 interaction inhibitors

High-Throughput Screening to Identify Inhibitors of the Type I Interferon–Major Histocompatibility Complex Class I Pathway in Skeletal Muscle

In vivo quantitative high-throughput screening for drug discovery and comparative toxicology

High-throughput screening identifies cell cycle-associated signaling cascades that regulate a multienzyme glucosome assembly in human cells

Structure–activity relationship of ipglycermide binding to phosphoglycerate mutases

First person – Patricia Dranchak

Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases

qHTSWaterfall: 3-dimensional visualization software for quantitative high-throughput screening (qHTS) data

A fission yeast platform for heterologous expression of mammalian adenylyl cyclases and high throughput screening

mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft

Synthesis and anticancer properties of water-soluble zinc ionophores

Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays

Nonsense suppressor therapies rescue peroxisome lipid metabolism and assembly in cells from patients with specific PEX gene mutations

Genome-Edited Coincidence and PMP22-HiBiT Fusion Reporter Cell Lines Enable an Artifact-Suppressive Quantitative High-Throughput Screening Strategy for PMP22 Gene-Dosage Disorder Drug Discovery

Diverse captive non-human primates with phytanic acid-deficient diets rich in plant products have substantial phytanic acid levels in their red blood cells

The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesis

Inhibition of natriuretic peptide receptor 1 reduces itch in mice

Protection Against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine

Development of a dopaminergic neurodegeneration assay using laser cytometry of Caenorhabditis elegans models of Parkinson's disease

A Macrocyclic Peptide Library with a Structurally Constrained Cyclopropane‐containing Building Block Leads to Thiol‐independent Inhibitors of Phosphoglycerate Mutase

Inheritance of recurrent exertional rhabdomyolysis in thoroughbreds

Abstract 19: Targeting Delta133p53 isoform with small-molecule compounds to modulate cellular senescence

Development of a dopaminergic neurodegeneration assay using laser cytometry of Caenorhabditis elegans models of Parkinson’s disease

Exclusion of linkage of the RYR1, CACNA1S, and ATP2A1 genes to recurrent exertional rhabdomyolysis in Thoroughbreds

Methotrexate-based PROTACs as DHFR-specific chemical probes

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