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Clinical Immunogenicity of rHuPH20, a Hyaluronidase Enabling Subcutaneous Drug Administration

The AAPS journal, 2015-09, Vol.17 (5), p.1144-1156

2015

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Erratum to: Clinical Immunogenicity of rHuPH20, a Hyaluronidase Enabling Subcutaneous Drug Administration

The AAPS journal, 2015-11, Vol.17 (6), p.1523-1524

2015

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The Collagenolytic Activity of Cathepsin K Is Unique among Mammalian Proteinases

The Journal of biological chemistry, 1998-11, Vol.273 (48), p.32347-32352

1998

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Recombinant human hyaluronidase PH20 (rHuPH20) facilitates subcutaneous infusions of large volumes of immunoglobulin in a swine model

Drug delivery and translational research, 2012-08, Vol.2 (4), p.254-264

2012

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Human Osteoclast Cathepsin K Is Processed Intracellularly Prior to Attachment and Bone Resorption

Journal of bone and mineral research, 2001-03, Vol.16 (3), p.478-486

2001

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Cathepsin K, but Not Cathepsins B, L, or S, Is Abundantly Expressed in Human Osteoclasts (∗)

The Journal of biological chemistry, 1996-05, Vol.271 (21), p.12511-12516

1996

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Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II

Biochemistry (Easton), 1989-10, Vol.28 (20), p.8154-8160

1989

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Mitoxantrone resistance in HL-60 leukemia cells: reduced nuclear topoisomerase II catalytic activity and drug-induced DNA cleavage in association with reduced expression of the topoisomerase II .beta. isoform

Biochemistry (Easton), 1991-10, Vol.30 (41), p.9953-9961

1991

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Peptide Aldehyde Inhibitors of Cathepsin K Inhibit Bone Resorption Both In Vitro and In Vivo

Journal of bone and mineral research, 1997-09, Vol.12 (9), p.1396-1406

1997

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The new partnership of genomics and chemistry for accelerated drug development

Current opinion in chemical biology, 1997-08, Vol.1 (2), p.151-156

1997

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Cathepsin K Knockout Mice Develop Osteopetrosis Due to a Deficit in Matrix Degradation but Not Demineralization

Journal of bone and mineral research, 1999-10, Vol.14 (10), p.1654-1663

1999

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Design and characterization of orally active Arg-Gly-Asp peptidomimetic vitronectin receptor antagonist SB 265123 for prevention of bone loss in osteoporosis

The Journal of pharmacology and experimental therapeutics, 1999-11, Vol.291 (2), p.612

1999

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In vitro and intracellular inhibition of topoisomerase II by the antitumor agent merbarone

Cancer research (Chicago, Ill.), 1989-05, Vol.49 (10), p.2578-2583

1989

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Proteolytic activity of human osteoclast cathepsin K. Expression, purification, activation, and substrate identification

The Journal of biological chemistry, 1996-05, Vol.271 (21), p.12517-12524

1996

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Localization of DNA Topoisomerase II in Chinese Hamster Fibroblasts by Confocal and Electron Microscopy

Experimental cell research, 1993, Vol.204 (1), p.73-81

1993

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A network-aware distributed storage cache for data intensive environments

Proceedings of the IEEE International Symposium on High Performance Distributed Computing, 1999, p.185-193

1999

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DNA Topoisomerase IIα is the Major Chromosome Protein Recognized by the Mitotic Phosphoprotein Antibody MPM-2

Proceedings of the National Academy of Sciences - PNAS, 1993-09, Vol.90 (18), p.8407-8411

1993

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Design of Potent and Selective Human Cathepsin K Inhibitors that Span the Active Site

Proceedings of the National Academy of Sciences - PNAS, 1997-12, Vol.94 (26), p.14249-14254

1997

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Integrating usability techniques into software development

IEEE software, 2001-01, Vol.18 (1), p.46-53

2001

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Characterization and Immunological Identification of cDNA Clones Encoding Two Human DNA Topoisomerase II Isozymes

Proceedings of the National Academy of Sciences - PNAS, 1989-12, Vol.86 (23), p.9431-9435

1989

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Proteolytic Activity of Human Osteoclast Cathepsin K

The Journal of biological chemistry, 1996-05, Vol.271 (21), p.12517-12524

1996

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Orally bioavailable nonpeptide vitronectin receptor antagonists with efficacy in an osteoporosis model

Bioorganic & medicinal chemistry letters, 1999-07, Vol.9 (13), p.1807-1812

1999

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Genomic Organization and Chromosome Localization of the Human Cathepsin K Gene (CTSK)

Genomics (San Diego, Calif.), 1997-04, Vol.41 (2), p.169-176

1997

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Probably, but More Information Is Forthcoming

Journal of bone and mineral research, 1998-02, Vol.13 (2), p.321-322

1998

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Differences between normal and ras-transformed NIH-3T3 cells in expression of the 170kD and 180kD forms of topoisomerase II

Cancer research (Chicago, Ill.), 1990-05, Vol.50 (10), p.2901-2908

1990

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Clinical Immunogenicity of rHuPH20, a Hyaluronidase Enabling Subcutaneous Drug Administration

Erratum to: Clinical Immunogenicity of rHuPH20, a Hyaluronidase Enabling Subcutaneous Drug Administration

The Collagenolytic Activity of Cathepsin K Is Unique among Mammalian Proteinases

Recombinant human hyaluronidase PH20 (rHuPH20) facilitates subcutaneous infusions of large volumes of immunoglobulin in a swine model

Human Osteoclast Cathepsin K Is Processed Intracellularly Prior to Attachment and Bone Resorption

Cathepsin K, but Not Cathepsins B, L, or S, Is Abundantly Expressed in Human Osteoclasts (∗)

Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II

Mitoxantrone resistance in HL-60 leukemia cells: reduced nuclear topoisomerase II catalytic activity and drug-induced DNA cleavage in association with reduced expression of the topoisomerase II .beta. isoform

Peptide Aldehyde Inhibitors of Cathepsin K Inhibit Bone Resorption Both In Vitro and In Vivo

The new partnership of genomics and chemistry for accelerated drug development

Cathepsin K Knockout Mice Develop Osteopetrosis Due to a Deficit in Matrix Degradation but Not Demineralization

Design and characterization of orally active Arg-Gly-Asp peptidomimetic vitronectin receptor antagonist SB 265123 for prevention of bone loss in osteoporosis

In vitro and intracellular inhibition of topoisomerase II by the antitumor agent merbarone

Proteolytic activity of human osteoclast cathepsin K. Expression, purification, activation, and substrate identification

Localization of DNA Topoisomerase II in Chinese Hamster Fibroblasts by Confocal and Electron Microscopy

A network-aware distributed storage cache for data intensive environments

DNA Topoisomerase IIα is the Major Chromosome Protein Recognized by the Mitotic Phosphoprotein Antibody MPM-2

Design of Potent and Selective Human Cathepsin K Inhibitors that Span the Active Site

Integrating usability techniques into software development

Characterization and Immunological Identification of cDNA Clones Encoding Two Human DNA Topoisomerase II Isozymes

Proteolytic Activity of Human Osteoclast Cathepsin K

Orally bioavailable nonpeptide vitronectin receptor antagonists with efficacy in an osteoporosis model

Genomic Organization and Chromosome Localization of the Human Cathepsin K Gene (CTSK)

Probably, but More Information Is Forthcoming

Differences between normal and ras-transformed NIH-3T3 cells in expression of the 170kD and 180kD forms of topoisomerase II

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