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Targeted Next-generation Sequencing of Advanced Prostate Cancer Identifies Potential Therapeutic Targets and Disease Heterogeneity

European urology, 2013-05, Vol.63 (5), p.920-926

2013

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Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing

Nature biotechnology, 2013-11, Vol.31 (11), p.1023-1031

2013

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Advanced urothelial carcinoma: next-generation sequencing reveals diverse genomic alterations and targets of therapy

Modern pathology, 2014-02, Vol.27 (2), p.271-280

2014

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A High Frequency of Activating Extracellular Domain ERBB2 (HER2) Mutation in Micropapillary Urothelial Carcinoma

Clinical cancer research, 2014, Vol.20 (1), p.68-75

2014

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Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (22), p.8699-8704

2012

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Relapsed Classic E-Cadherin (CDH1)―Mutated Invasive Lobular Breast Cancer Shows a High Frequency of HER2 (ERBB2) Gene Mutations

Clinical cancer research, 2013-05, Vol.19 (10), p.2668-2676

2013

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Response of an ERBB2-mutated inflammatory breast carcinoma to human epidermal growth factor receptor 2-targeted therapy

Journal of clinical oncology, 2014-09, Vol.32 (25), p.e88-e91

2014

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Comprehensive Genomic Profiling of Relapsed and Metastatic Adenoid Cystic Carcinomas by Next-generation Sequencing Reveals Potential New Routes to Targeted Therapies

The American journal of surgical pathology, 2014-02, Vol.38 (2), p.235-238

2014

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Colchicine, aspirin, and montelukast - A case of successful combined pharmacotherapy for adult multisystem inflammatory syndrome in COVID-19

Journal of global infectious diseases, 2020-10, Vol.12 (4), p.221-224

2020

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Isolation and proteomic analysis of platelets by SELDI-TOF MS

Methods in molecular biology (Clifton, N.J.), 2012, Vol.818, p.153

2012

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Development of a PD-L1 multiplex immunofluorescence assay with advanced visual analysis for understanding the tumor microenvironment

Journal of clinical oncology, 2019-05, Vol.37 (15_suppl), p.e14283-e14283

2019

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Abstract 5652: Validation of novel InSituPlex™ technology utilizing standard chromogenic IHC and multiplexed tyramide-based immunofluorescence

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.5652-5652

2018

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Abstract 5657: Use of a novel immunofluorescence multiplexing technology, InSituPlex™, for the simultaneous detection of immune cells in multiple cancer types

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.5657-5657

2018

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Abstract LB-275: Measuring concordance of CD8 and PD-L1 expression in non-small cell lung cancer between a novel multiplex immunofluorescence assay and a brightfield laboratory developed test

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.LB-275-LB-275

2020

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Abstract 4986: Utilizing image analysis to characterize an 8-plex immunofluorescence immune checkpoint biomarker panel within the tumor tissue microenvironment

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.4986-4986

2020

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Alterations of p53 are common in early stage prostate cancer

Canadian journal of urology, 2003-08, Vol.10 (4), p.1924

2003

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Abstract 4569: Intra- and inter-run assessment of reproducibility and quantification of UltiMapper™ I/O APC and T-act kits for tissue multiplexing

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.4569-4569

2019

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Abstract 1677: Understanding the TME: Advanced analysis and visualization of multiplexed fluorescence images

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.1677-1677

2019

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Abstract 4989: Introduction of a robust workflow for the whole-side acquisition and co-registration of multiplex immunofluorescence tissue images for analysis of a 9-color, 8-marker immunophenotyping assay

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.4989-4989

2020

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Preliminary correlative analysis of PD-L1 expression from the SUNRISE study

Journal of clinical oncology, 2017-05, Vol.35 (15_suppl), p.11603-11603

2017

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2022 White Paper on Recent Issues in Bioanalysis: FDA Draft Guidance on Immunogenicity Information in Prescription Drug Labeling, LNP & Viral Vectors Therapeutics/Vaccines Immunogenicity, Prolongation Effect, ADA Affinity, Risk-based Approaches, NGS, qPCR, ddPCR Assays

Bioanalysis, 2023-07, Vol.15 (14), p.773-814

2023

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2023 White Paper on Recent Issues in Bioanalysis: EU IVDR 2017/746 Implementation/Impact, IVD/CDx/CLIA Approved Assays, High Dimensional Cytometry, Multiplexing Technologies, LBA Tissue Analysis, Vaccine Study Endpoints, Cell-Based Assays for Biomarkers, Cell Therapy and Vaccines ( PART 2 – Recommendations on Development & Validation of Biomarkers, IVD, CDx, Cell-Based, Flow Cytometry, Ligand-Binding and Enzyme Assays; Advanced Critical Reagents Strategies)

Bioanalysis, 2024-04, Vol.16 (8), p.179-220

2024

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Abstract 4699: Analytical validation of solid tumor fusion gene detection in a comprehensive NGS-based clinical cancer genomic test

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.4699-4699

2014

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Mutations in ribonuclease L gene do not occur at a greater frequency in patients with familial prostate cancer compared with patients with sporadic prostate cancer

Clinical prostate cancer, 2003-12, Vol.2 (3), p.177-180

2003

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Targeted Next-generation Sequencing of Advanced Prostate Cancer Identifies Potential Therapeutic Targets and Disease Heterogeneity

Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing

Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies

Advanced urothelial carcinoma: next-generation sequencing reveals diverse genomic alterations and targets of therapy

A High Frequency of Activating Extracellular Domain ERBB2 (HER2) Mutation in Micropapillary Urothelial Carcinoma

Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer

Relapsed Classic E-Cadherin (CDH1)―Mutated Invasive Lobular Breast Cancer Shows a High Frequency of HER2 (ERBB2) Gene Mutations

Response of an ERBB2-mutated inflammatory breast carcinoma to human epidermal growth factor receptor 2-targeted therapy

Comprehensive Genomic Profiling of Relapsed and Metastatic Adenoid Cystic Carcinomas by Next-generation Sequencing Reveals Potential New Routes to Targeted Therapies

Colchicine, aspirin, and montelukast - A case of successful combined pharmacotherapy for adult multisystem inflammatory syndrome in COVID-19

Isolation and proteomic analysis of platelets by SELDI-TOF MS

Development of a PD-L1 multiplex immunofluorescence assay with advanced visual analysis for understanding the tumor microenvironment

Abstract 5652: Validation of novel InSituPlex™ technology utilizing standard chromogenic IHC and multiplexed tyramide-based immunofluorescence

Abstract 5657: Use of a novel immunofluorescence multiplexing technology, InSituPlex™, for the simultaneous detection of immune cells in multiple cancer types

Abstract LB-275: Measuring concordance of CD8 and PD-L1 expression in non-small cell lung cancer between a novel multiplex immunofluorescence assay and a brightfield laboratory developed test

Abstract 4986: Utilizing image analysis to characterize an 8-plex immunofluorescence immune checkpoint biomarker panel within the tumor tissue microenvironment

Alterations of p53 are common in early stage prostate cancer

Abstract 4569: Intra- and inter-run assessment of reproducibility and quantification of UltiMapper™ I/O APC and T-act kits for tissue multiplexing

Abstract 1677: Understanding the TME: Advanced analysis and visualization of multiplexed fluorescence images

Abstract 4989: Introduction of a robust workflow for the whole-side acquisition and co-registration of multiplex immunofluorescence tissue images for analysis of a 9-color, 8-marker immunophenotyping assay

Preliminary correlative analysis of PD-L1 expression from the SUNRISE study

2022 White Paper on Recent Issues in Bioanalysis: FDA Draft Guidance on Immunogenicity Information in Prescription Drug Labeling, LNP & Viral Vectors Therapeutics/Vaccines Immunogenicity, Prolongation Effect, ADA Affinity, Risk-based Approaches, NGS, qPCR, ddPCR Assays

Abstract 4699: Analytical validation of solid tumor fusion gene detection in a comprehensive NGS-based clinical cancer genomic test

Mutations in ribonuclease L gene do not occur at a greater frequency in patients with familial prostate cancer compared with patients with sporadic prostate cancer

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