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Ketopiperazine-based renin inhibitors: Optimization of the “C” ring

Bioorganic & medicinal chemistry letters, 2006-05, Vol.16 (9), p.2500-2504

2006

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Discovery of novel non-peptidic ketopiperazine-based renin inhibitors

Bioorganic & medicinal chemistry, 2005-04, Vol.13 (7), p.2657-2664

2005

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Practical Synthesis of 1-Aryl-6-(hydroxymethyl)-2-ketopiperazines via a 6-exo Amide−Epoxide Cyclization

Organic letters, 2004-10, Vol.6 (22), p.4069-4072

2004

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Preparation, Antiepileptic Activity, and Cardiovascular Safety of Dihydropyrazoles as Brain-Penetrant T‑Type Calcium Channel Blockers

Journal of medicinal chemistry, 2016-09, Vol.59 (18), p.8398-8411

2016

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The Discovery and Structure-Activity Relationships of 1,2,3,6-Tetrahydro-4-phenyl-1-[(arylcyclohexenyl)alkyl]pyridines. Dopamine Autoreceptor Agonists and Potential Antipsychotic Agents

Journal of medicinal chemistry, 1994-10, Vol.37 (21), p.3523-3533

1994

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Inhibition of interleukin-1β converting enzyme (ICE or caspase 1) by aspartyl acyloxyalkyl ketones and aspartyl amidooxyalkyl ketones

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (17), p.5089-5094

2010

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Inhibition of interteukin-1β converting enzyme (ICE or caspase 1) by aspartyl acyloxyalkyl ketones and aspartyl amidooxyalkyl ketones

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (17), p.5089-5094

2010

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Identification, Characterization and Pharmacological Profile of Three Metabolites of (R)-(+)-1,2,3,6-Tetrahydro-4-phenyl-1-[(3-phenylcyclohexen-1-yl)methyl]p yridine (CI-1007), a Dopamine Autoreceptor Agonist and Potential Antipsychotic Agent

Journal of medicinal chemistry, 1995-12, Vol.38 (26), p.5007-5014

1995

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Inhibition of interleukin-1beta converting enzyme (ICE or caspase 1) by aspartyl acyloxyalkyl ketones and aspartyl amidooxyalkyl ketones

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (17), p.5089-5094

2010

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8-amino-6-(arylsulphonyl)-5-nitroquinolines: novel nonpeptide neuropeptide Y1 receptor antagonists

Bioorganic & medicinal chemistry letters, 1996-08, Vol.6 (15), p.1809-1814

1996

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Reconcillation and Rectification of Process Flow and Inventory Data

Industrial & engineering chemistry process design and development, 1976-01, Vol.15 (1), p.175-183

1976

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Discovery of selective dopamine D3 ligands: I. Dimeric 2-[4-(3-aminopropoxy)phenyl]benzimidazole antagonists

Bioorganic & medicinal chemistry letters, 1995-11, Vol.5 (21), p.2541-2546

1995

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Safety incentives: myths and realities

Occupational health & safety, 2004-01, Vol.73 (1), p.62

2004

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Inter-Intraphase Temperature Gradients in Fresh and Deactivated Catalyst Particles

Industrial & engineering chemistry fundamentals, 1977-05, Vol.16 (2), p.270-272

1977

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EXPERIMENTAL AND MODELING STUDY OF THE INFLUENCE OF DEACTIVATION AND CATALYST DILUTION ON A NONISOTHERMAL CATALYTIC PELLET

DOWNING, DENNIS MICHAEL

1977

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ProQuest

A HISTORICAL STUDY OF THE ORIGINS OF THE PHYSICAL ASPECTS OF THE RESTORATION PLAYHOUSE WITH SPECIAL EMPHASIS ON THE DORSET GARDEN THEATRE

WILSON, DENNIS DOWNING

1975

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ProQuest

THE EFFECTS OF SPEECH RATE, LISTENER APTITUDE, AND PASSAGE LISTENABILITY UPON LISTENING COMPREHENSION

DOWNING, DENNIS IVAN

1971

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ProQuest

Practical Synthesis of 1-Aryl-6-(hydroxymethyl)-2-ketopiperazines via a 6-exo Amide-Epoxide Cyclization

ChemInform, 2005-02, Vol.36 (6), p.no-no

2005

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INTENSITY PERTURBATIONS IN THE 3.0 MICRON BANDS OF CARBON-DIOXIDE

DOWNING, HARRY DENNIS

1973

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ProQuest

An Epidemiologic Investigation of Potential Risk Factors for Nodding Syndrome in Kitgum District, Uganda

PloS one, 2013-06, Vol.8 (6), p.e66419

2013

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Pathogenic Germline Mutations in DNA Repair Genes in Combination With Cancer Treatment Exposures and Risk of Subsequent Neoplasms Among Long-Term Survivors of Childhood Cancer

Journal of clinical oncology, 2020-08, Vol.38 (24), p.2728-2740

2020

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Using Continuous Underway Isotope Measurements To Map Water Residence Time in Hydrodynamically Complex Tidal Environments

Environmental science & technology, 2016-12, Vol.50 (24), p.13387-13396

2016

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A community-based framework for aquatic ecosystem models

Hydrobiologia, 2012-03, Vol.683 (1), p.25-34

2012

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Milestones to the Discovery of T-type Calcium Channel Blockers for the Treatment of Generalized Epilepsies

Ketopiperazine-based renin inhibitors: Optimization of the “C” ring

Discovery of novel non-peptidic ketopiperazine-based renin inhibitors

Practical Synthesis of 1-Aryl-6-(hydroxymethyl)-2-ketopiperazines via a 6-exo Amide−Epoxide Cyclization

Preparation, Antiepileptic Activity, and Cardiovascular Safety of Dihydropyrazoles as Brain-Penetrant T‑Type Calcium Channel Blockers

The Discovery and Structure-Activity Relationships of 1,2,3,6-Tetrahydro-4-phenyl-1-[(arylcyclohexenyl)alkyl]pyridines. Dopamine Autoreceptor Agonists and Potential Antipsychotic Agents

Inhibition of interleukin-1β converting enzyme (ICE or caspase 1) by aspartyl acyloxyalkyl ketones and aspartyl amidooxyalkyl ketones

Inhibition of interteukin-1β converting enzyme (ICE or caspase 1) by aspartyl acyloxyalkyl ketones and aspartyl amidooxyalkyl ketones

Identification, Characterization and Pharmacological Profile of Three Metabolites of (R)-(+)-1,2,3,6-Tetrahydro-4-phenyl-1-[(3-phenylcyclohexen-1-yl)methyl]p yridine (CI-1007), a Dopamine Autoreceptor Agonist and Potential Antipsychotic Agent

Inhibition of interleukin-1beta converting enzyme (ICE or caspase 1) by aspartyl acyloxyalkyl ketones and aspartyl amidooxyalkyl ketones

8-amino-6-(arylsulphonyl)-5-nitroquinolines: novel nonpeptide neuropeptide Y1 receptor antagonists

Reconcillation and Rectification of Process Flow and Inventory Data

Discovery of selective dopamine D3 ligands: I. Dimeric 2-[4-(3-aminopropoxy)phenyl]benzimidazole antagonists

Safety incentives: myths and realities

Inter-Intraphase Temperature Gradients in Fresh and Deactivated Catalyst Particles

EXPERIMENTAL AND MODELING STUDY OF THE INFLUENCE OF DEACTIVATION AND CATALYST DILUTION ON A NONISOTHERMAL CATALYTIC PELLET

A HISTORICAL STUDY OF THE ORIGINS OF THE PHYSICAL ASPECTS OF THE RESTORATION PLAYHOUSE WITH SPECIAL EMPHASIS ON THE DORSET GARDEN THEATRE

THE EFFECTS OF SPEECH RATE, LISTENER APTITUDE, AND PASSAGE LISTENABILITY UPON LISTENING COMPREHENSION

Practical Synthesis of 1-Aryl-6-(hydroxymethyl)-2-ketopiperazines via a 6-exo Amide-Epoxide Cyclization

INTENSITY PERTURBATIONS IN THE 3.0 MICRON BANDS OF CARBON-DIOXIDE

An Epidemiologic Investigation of Potential Risk Factors for Nodding Syndrome in Kitgum District, Uganda

Pathogenic Germline Mutations in DNA Repair Genes in Combination With Cancer Treatment Exposures and Risk of Subsequent Neoplasms Among Long-Term Survivors of Childhood Cancer

Clinical, neurological, and electrophysiological features of nodding syndrome in Kitgum, Uganda: an observational case series

Using Continuous Underway Isotope Measurements To Map Water Residence Time in Hydrodynamically Complex Tidal Environments

A community-based framework for aquatic ecosystem models

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