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International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases

Pharmacological reviews, 2017-04, Vol.69 (2), p.93-139

2017

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The extracellular loop 2 (ECL2) of the human histamine H4 receptor substantially contributes to ligand binding and constitutive activity

PloS one, 2015, Vol.10 (1), p.e0117185

2015

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Functional Selectivity of GPCR Ligand Stereoisomers: New Pharmacological Opportunities

Molecular pharmacology, 2009-01, Vol.75 (1), p.13-18

2009

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Paradoxical stimulatory effects of the "standard" histamine H4-receptor antagonist JNJ7777120: the H4 receptor joins the club of 7 transmembrane domain receptors exhibiting functional selectivity

Molecular pharmacology, 2011-04, Vol.79 (4), p.631-638

2011

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Synthesis and Structure−Activity Relationships of Cyanoguanidine-Type and Structurally Related Histamine H4 Receptor Agonists

Journal of medicinal chemistry, 2009-10, Vol.52 (20), p.6297-6313

2009

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Expression and functional properties of canine, rat, and murine histamine H4 receptors in Sf9 insect cells

Naunyn-Schmiedeberg's archives of pharmacology, 2011-05, Vol.383 (5), p.457-470

2011

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Structure-bias relationships for fenoterol stereoisomers in six molecular and cellular assays at the β2-adrenoceptor

Naunyn-Schmiedeberg's archives of pharmacology, 2015-01, Vol.388 (1), p.51-65

2015

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Constitutive activity and ligand selectivity of human, guinea pig, rat, and canine histamine H2 receptors

The Journal of pharmacology and experimental therapeutics, 2007-06, Vol.321 (3), p.983

2007

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Inhibitors of Bacillus anthracis edema factor

Pharmacology & therapeutics (Oxford), 2013-11, Vol.140 (2), p.200-212

2013

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Mammalian Nucleotidyl Cyclases and Their Nucleotide Binding Sites

Handbook of experimental pharmacology, 2017, Vol.238, p.49-66

2017

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Towards selective inhibitors of adenylyl cyclase toxin from Bordetella pertussis

Trends in microbiology (Regular ed.), 2012-07, Vol.20 (7), p.343-351

2012

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Different Roles of N-Terminal and C-Terminal Domains in Calmodulin for Activation of Bacillus anthracis Edema Factor

Toxins, 2015-07, Vol.7 (7), p.2598-2614

2015

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Molecular Analysis of the Interaction of Bordetella pertussis Adenylyl Cyclase with Fluorescent Nucleotides

Molecular pharmacology, 2007-09, Vol.72 (3), p.526-535

2007

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Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor

The Journal of pharmacology and experimental therapeutics, 2003-06, Vol.305 (3), p.1104

2003

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The Bivalent Ligand Approach Leads to Highly Potent and Selective Acylguanidine-Type Histamine H2 Receptor Agonists

Journal of medicinal chemistry, 2012-02, Vol.55 (3), p.1147-1160

2012

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Mutations of Cys-17 and Ala-271 in the human histamine H2 receptor determine the species selectivity of guanidine-type agonists and increase constitutive activity

The Journal of pharmacology and experimental therapeutics, 2007-06, Vol.321 (3), p.975

2007

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A Single Amino Acid Exchange Inverts Susceptibility of Related Receptor Tyrosine Kinases for the ATP Site Inhibitor STI-571

The Journal of biological chemistry, 2003-02, Vol.278 (7), p.5148-5155

2003

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Structure-activity relationships of histamine H2 receptor ligands

Mini reviews in medicinal chemistry, 2004-11, Vol.4 (9), p.941-954

2004

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Inhibition of FLT3 and PDGFR tyrosine kinase activity by bis(benzo[ b]furan-2-yl)methanones

Bioorganic & medicinal chemistry, 2007-03, Vol.15 (5), p.2187-2197

2007

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Molecular and cellular analysis of human histamine receptor subtypes

Trends in pharmacological sciences (Regular ed.), 2013-01, Vol.34 (1), p.33-58

2013

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Design and biological evaluation of tetrahydro-β-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors

European journal of medicinal chemistry, 2018-05, Vol.152, p.329-357

2018

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Paradoxical Stimulatory Effects of the “Standard” Histamine H 4 -Receptor Antagonist JNJ7777120: the H 4 Receptor Joins the Club of 7 Transmembrane Domain Receptors Exhibiting Functional Selectivity

Molecular pharmacology, 2011-04, Vol.79 (4), p.631-638

2011

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Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors

Journal of medicinal chemistry, 2018-04, Vol.61 (8), p.3454-3477

2018

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Histamine H 4 receptor agonists

Bioorganic & medicinal chemistry letters, 2010-12, Vol.20 (24), p.7191-7199

2010

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Histamine H4 receptor agonists

Bioorganic & medicinal chemistry letters, 2010-12, Vol.20 (24), p.7191-7199

2010

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International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases

The extracellular loop 2 (ECL2) of the human histamine H4 receptor substantially contributes to ligand binding and constitutive activity

Functional Selectivity of GPCR Ligand Stereoisomers: New Pharmacological Opportunities

Paradoxical stimulatory effects of the "standard" histamine H4-receptor antagonist JNJ7777120: the H4 receptor joins the club of 7 transmembrane domain receptors exhibiting functional selectivity

Synthesis and Structure−Activity Relationships of Cyanoguanidine-Type and Structurally Related Histamine H4 Receptor Agonists

Expression and functional properties of canine, rat, and murine histamine H4 receptors in Sf9 insect cells

Structure-bias relationships for fenoterol stereoisomers in six molecular and cellular assays at the β2-adrenoceptor

Constitutive activity and ligand selectivity of human, guinea pig, rat, and canine histamine H2 receptors

Inhibitors of Bacillus anthracis edema factor

Mammalian Nucleotidyl Cyclases and Their Nucleotide Binding Sites

Towards selective inhibitors of adenylyl cyclase toxin from Bordetella pertussis

Different Roles of N-Terminal and C-Terminal Domains in Calmodulin for Activation of Bacillus anthracis Edema Factor

Molecular Analysis of the Interaction of Bordetella pertussis Adenylyl Cyclase with Fluorescent Nucleotides

Multiple differences in agonist and antagonist pharmacology between human and guinea pig histamine H1-receptor

The Bivalent Ligand Approach Leads to Highly Potent and Selective Acylguanidine-Type Histamine H2 Receptor Agonists

Mutations of Cys-17 and Ala-271 in the human histamine H2 receptor determine the species selectivity of guanidine-type agonists and increase constitutive activity

A Single Amino Acid Exchange Inverts Susceptibility of Related Receptor Tyrosine Kinases for the ATP Site Inhibitor STI-571

Structure-activity relationships of histamine H2 receptor ligands

Inhibition of FLT3 and PDGFR tyrosine kinase activity by bis(benzo[ b]furan-2-yl)methanones

Molecular and cellular analysis of human histamine receptor subtypes

Design and biological evaluation of tetrahydro-β-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors

Paradoxical Stimulatory Effects of the “Standard” Histamine H 4 -Receptor Antagonist JNJ7777120: the H 4 Receptor Joins the Club of 7 Transmembrane Domain Receptors Exhibiting Functional Selectivity

Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors

Histamine H 4 receptor agonists

Histamine H4 receptor agonists

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