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The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function

Cancer research (Chicago, Ill.), 2005-02, Vol.65 (4), p.1489-1496

2005

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Heparin Octasaccharides Inhibit Angiogenesis In vivo

Clinical cancer research, 2005-11, Vol.11 (22), p.8172-8179

2005

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Phase I/II Pilot Study of Intravesical Apaziquone (EO9) for Superficial Bladder Cancer

The Journal of urology, 2006-10, Vol.176 (4), p.1344-1348

2006

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Preclinical evaluation of amino acid prodrugs of novel antitumor 2-(4-amino-3-methylphenyl)benzothiazoles

Molecular cancer therapeutics, 2002-02, Vol.1 (4), p.239

2002

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Cytochrome P450 1B1 (CYP1B1) is overexpressed in human colon adenocarcinomas relative to normal colon: implications for drug development

Molecular cancer therapeutics, 2003-06, Vol.2 (6), p.527-534

2003

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Methionine dependence of tumours: A biochemical strategy for optimizing paclitaxel chemosensitivity in vitro

Biochemical pharmacology, 2006-03, Vol.71 (6), p.772-778

2006

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Analysis of cell-cycle kinetics and sulfur amino acid metabolism in methionine-dependent tumor cell lines; the effect of homocysteine supplementation

Biochemical pharmacology, 2004-04, Vol.67 (8), p.1587-1599

2004

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A pharmacological approach for the selection of potential anticancer agents

Alternatives to laboratory animals, 2004-09, Vol.32 Suppl 2 (2_suppl), p.41-48

Double, John A

2004

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Telomerase as a therapeutic target. Therapeutic potential of telomerase inhibitors

Methods in molecular biology (Clifton, N.J.), 2002, Vol.191, p.209

Double, John A

2002

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The role of p53 in the chemotherapeutic responses to cisplatin, doxorubicin and 5-fluorouracil treatment

International journal of oncology, 2004-01, Vol.24 (1), p.115

2004

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Angiogenesis in the hollow fiber tumor model influences drug delivery to tumor cells : Implications for anticancer drug screening programs

Cancer research (Chicago, Ill.), 1998-12, Vol.58 (23), p.5263-5266

1998

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Genotyping of NAD(P)H:quinone oxidoreductase (NQO1) in a panel of human tumor xenografts: relationship between genotype status, NQO1 activity and the response of xenografts to Mitomycin C chemotherapy in vivo

Biochemical pharmacology, 2001-11, Vol.62 (10), p.1371-1377

2001

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Toxicity testing in the development of anticancer drugs

The lancet oncology, 2002-07, Vol.3 (7), p.438-442

2002

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Pharmacokinetics of PK1 and Doxorubicin in Experimental Colon Tumor Models with Differing Responses to PK1

Clinical cancer research, 1999-11, Vol.5 (11), p.3682-3688

1999

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The delivery of antisense therapeutics

Advanced drug delivery reviews, 2000-10, Vol.44 (1), p.3-21

2000

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Establishment and characterisation of new cell lines from human breast tumours initially established as tumour xenografts in NMRI nude mice

Breast cancer research and treatment, 1997-05, Vol.43 (3), p.247-258

1997

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Nucleoside Analogs. 14. The Synthesis and Antitumor Activity in Mice of Molecular Combinations of 5-Fluorouracil and N-(2-Chloroethyl)-N-nitrosourea Moieties Separated by a Three-Carbon Chain

Journal of medicinal chemistry, 1996-03, Vol.39 (7), p.1403-1412

1996

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Antitumour activity of S-p-bromobenzylglutathione cyclopentyl diester in vitro and in vivo: Inhibition of glyoxalase I and induction of apoptosis

Biochemical pharmacology, 1996-05, Vol.51 (10), p.1365-1372

1996

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Characterization of the major metabolites of flavone acetic acid and comparison of their disposition in humans and mice

Cancer research (Chicago, Ill.), 1989-07, Vol.49 (13), p.3587-3593

1989

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Distribution, metabolism and tumoricidal activity of doxorubicin administered in sorbitan monostearate (Span 60) niosomes in the mouse

Pharmaceutical research, 1995-07, Vol.12 (7), p.1019-1024

1995

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The G-quadruplex-lnteractive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function

Cancer research (Chicago, Ill.), 2005, Vol.65 (4), p.1489-1496

2005

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Sequence and chemistry requirements for a novel aptameric oligonucleotide inhibitor of EGF receptor tyrosine kinase activity

Biochemical pharmacology, 2002-06, Vol.63 (12), p.2187-2195

2002

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Genotyping of NAD(P)H:quinone oxidoreductase (NQO1) in a panel of human tumor xenografts: relationship between genotype status, NQO1 activity and the response of xenografts to Mitomycin C chemotherapy in vivo11Abbreviations: NQO1, NAD(P)H,Quinone oxidoreductase; MMC, Mitomycin C; PCR-RFLP, Polymerase chain reaction restriction fragment length polymorphism; and RH1, 2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone

Biochemical pharmacology, 2001-12, Vol.62 (10), p.1371-1377

2001

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The Activity of Doxorubicin Niosomes Against an Ovarian Cancer Cell Line and Three in Vivo Mouse Tumour Models

Journal of drug targeting, 1996, Vol.3 (5), p.399-409

1996

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The delivery of antisense therapeutics: Design and Delivery of Antisense Oligonucleotides and Ribozymes

Advanced drug delivery reviews, 2000, Vol.44 (1), p.3-21

2000

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The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function

Heparin Octasaccharides Inhibit Angiogenesis In vivo

Phase I/II Pilot Study of Intravesical Apaziquone (EO9) for Superficial Bladder Cancer

Preclinical evaluation of amino acid prodrugs of novel antitumor 2-(4-amino-3-methylphenyl)benzothiazoles

Cytochrome P450 1B1 (CYP1B1) is overexpressed in human colon adenocarcinomas relative to normal colon: implications for drug development

Methionine dependence of tumours: A biochemical strategy for optimizing paclitaxel chemosensitivity in vitro

Analysis of cell-cycle kinetics and sulfur amino acid metabolism in methionine-dependent tumor cell lines; the effect of homocysteine supplementation

A pharmacological approach for the selection of potential anticancer agents

Telomerase as a therapeutic target. Therapeutic potential of telomerase inhibitors

The role of p53 in the chemotherapeutic responses to cisplatin, doxorubicin and 5-fluorouracil treatment

Angiogenesis in the hollow fiber tumor model influences drug delivery to tumor cells : Implications for anticancer drug screening programs

Genotyping of NAD(P)H:quinone oxidoreductase (NQO1) in a panel of human tumor xenografts: relationship between genotype status, NQO1 activity and the response of xenografts to Mitomycin C chemotherapy in vivo

Toxicity testing in the development of anticancer drugs

Pharmacokinetics of PK1 and Doxorubicin in Experimental Colon Tumor Models with Differing Responses to PK1

The delivery of antisense therapeutics

Establishment and characterisation of new cell lines from human breast tumours initially established as tumour xenografts in NMRI nude mice

Nucleoside Analogs. 14. The Synthesis and Antitumor Activity in Mice of Molecular Combinations of 5-Fluorouracil and N-(2-Chloroethyl)-N-nitrosourea Moieties Separated by a Three-Carbon Chain

Antitumour activity of S-p-bromobenzylglutathione cyclopentyl diester in vitro and in vivo: Inhibition of glyoxalase I and induction of apoptosis

Characterization of the major metabolites of flavone acetic acid and comparison of their disposition in humans and mice

Distribution, metabolism and tumoricidal activity of doxorubicin administered in sorbitan monostearate (Span 60) niosomes in the mouse

The G-quadruplex-lnteractive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function

Sequence and chemistry requirements for a novel aptameric oligonucleotide inhibitor of EGF receptor tyrosine kinase activity

The Activity of Doxorubicin Niosomes Against an Ovarian Cancer Cell Line and Three in Vivo Mouse Tumour Models

The delivery of antisense therapeutics: Design and Delivery of Antisense Oligonucleotides and Ribozymes

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