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Regulatory Subunit of Protein Kinase A: Structure of Deletion Mutant with cAMP Binding Domains

Science (American Association for the Advancement of Science), 1995-08, Vol.269 (5225), p.807-813

1995

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Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates

The Journal of biological chemistry, 1990-06, Vol.265 (18), p.10484-10491

1990

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Spatiotemporal Dynamics of Guanosine 3′,5′-Cyclic Monophosphate Revealed by a Genetically Encoded, Fluorescent Indicator

Proceedings of the National Academy of Sciences - PNAS, 2001-02, Vol.98 (5), p.2437-2442

2001

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p38 MAPK Activation Elevates Serotonin Transport Activity via a Trafficking-independent, Protein Phosphatase 2A-dependent Process

The Journal of biological chemistry, 2005-04, Vol.280 (16), p.15649-15658

2005

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Compartmentalized Phosphodiesterase-2 Activity Blunts β-Adrenergic Cardiac Inotropy via an NO/cGMP-Dependent Pathway

Circulation research, 2006-02, Vol.98 (2), p.226-234

2006

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cGMP Catabolism by Phosphodiesterase 5A Regulates Cardiac Adrenergic Stimulation by NOS3-Dependent Mechanism

Circulation research, 2005-01, Vol.96 (1), p.100-109

2005

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Poly-l-proline type II peptide mimics as probes of the active site occupancy requirements of cGMP-dependent protein kinase

The journal of peptide research, 2005-10, Vol.66 (4), p.151-159

2005

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Determination of Cyclic Nucleotide-Dependent Protein Kinase Substrate Specificity by the Use of Peptide Libraries on Cellulose Paper

Biochemistry (Easton), 1995-08, Vol.34 (33), p.10569-10577

1995

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Active Site Mutations Define the Pathway for the Cooperative Activation of cAMP-Dependent Protein Kinase

Biochemistry (Easton), 1996-03, Vol.35 (9), p.2934-2942

1996

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Role of MgATP in the activation and reassociation of cAMP-dependent protein kinase I : consequences of replacing the essential arginine in cAMP binding site A

Biochemistry (Easton), 1991-01, Vol.30 (3), p.733-739

1991

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( RP)-cAMPS inhibits the cAMP-dependent protein kinase by blocking the cAMP-induced conformational transition

FEBS letters, 1995-11, Vol.375 (3), p.231-234

Dostmann, Wolfgang R.G.

1995

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Crystallization of a Deletion Mutant of the R-subunit of cAMP Dependent Protein Kinase

Journal of molecular biology, 1993-04, Vol.230 (3), p.1091-1093

1993

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Peptide blockers of PKG inhibit ROS generation by acetylcholine and bradykinin in cardiomyocytes but fail to block protection in the whole heart

American journal of physiology. Heart and circulatory physiology, 2005-04, Vol.288 (4), p.H1976-H1981

2005

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Crosstalk between Domains in the Regulatory Subunit of cAMP-Dependent Protein Kinase: Influence of Amino Terminus on cAMP Binding and Holoenzyme Formation

Biochemistry (Easton), 1994-06, Vol.33 (23), p.7485-7494

1994

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A role for cyclic-GMP dependent protein kinase in anoikis

Cellular signalling, 2006-06, Vol.18 (6), p.882-888

2006

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Inhibition of cGMP-Dependent Protein Kinase Reverses Phenotypic Modulation of Vascular Smooth Muscle Cells

Journal of cardiovascular pharmacology, 2005-05, Vol.45 (5), p.404-413

2005

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Identifying the molecular switches that determine whether (Rp)-cAMPS functions as an antagonist or an agonist in the activation of cAMP-dependent protein kinase I

Biochemistry (Easton), 1991-09, Vol.30 (35), p.8710-8716

1991

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The catalytic domain of the cGMP-dependent protein kinase Ialpha modulates the cGMP-binding characteristics of its regulatory domain

FEBS letters, 1996-12, Vol.398 (2-3), p.206-210

1996

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Isoleucine 368 is involved in low-affinity binding of N6-modified cAMP analogues to site B of the regulatory subunit of cAMP-dependent protein kinase I

Biochemical journal, 1996-05, Vol.316 ( Pt 1) (Pt 1), p.337-343

1996

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Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase Ialpha inhibit NO-induced cerebral dilation

Proceedings of the National Academy of Sciences - PNAS, 2000-12, Vol.97 (26), p.14772-14777

2000

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Delineation of selective cyclic GMP-dependent protein kinase Ialpha substrate and inhibitor peptides based on combinatorial peptide libraries on paper

Pharmacology & therapeutics (Oxford), 1999-05, Vol.82 (2-3), p.373

1999

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Expression of a chimeric, cGMP-sensitive regulatory subunit of the cAMP-dependent protein kinase type I alpha

FEBS letters, 1995-11, Vol.374 (3), p.356

1995

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Identification of the amino acid sequences responsible for high affinity activation of cGMP kinase Ialpha

The Journal of biological chemistry, 1997-04, Vol.272 (16), p.10522

1997

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Ala335 is essential for high‐affinity cAMP‐binding of both sites A and B of cAMP‐dependent protein kinase type I

FEBS letters, 1995-04, Vol.362 (3), p.291-294

1995

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Culture conditions influence uptake and intracellular localization of the membrane permeable cGMP-dependent protein kinase inhibitor DT-2

Frontiers in bioscience, 2005-05, Vol.10 (1-3), p.1302

2005

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Regulatory Subunit of Protein Kinase A: Structure of Deletion Mutant with cAMP Binding Domains

Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates

Spatiotemporal Dynamics of Guanosine 3′,5′-Cyclic Monophosphate Revealed by a Genetically Encoded, Fluorescent Indicator

p38 MAPK Activation Elevates Serotonin Transport Activity via a Trafficking-independent, Protein Phosphatase 2A-dependent Process

Compartmentalized Phosphodiesterase-2 Activity Blunts β-Adrenergic Cardiac Inotropy via an NO/cGMP-Dependent Pathway

cGMP Catabolism by Phosphodiesterase 5A Regulates Cardiac Adrenergic Stimulation by NOS3-Dependent Mechanism

Poly-l-proline type II peptide mimics as probes of the active site occupancy requirements of cGMP-dependent protein kinase

Determination of Cyclic Nucleotide-Dependent Protein Kinase Substrate Specificity by the Use of Peptide Libraries on Cellulose Paper

Active Site Mutations Define the Pathway for the Cooperative Activation of cAMP-Dependent Protein Kinase

Role of MgATP in the activation and reassociation of cAMP-dependent protein kinase I : consequences of replacing the essential arginine in cAMP binding site A

( RP)-cAMPS inhibits the cAMP-dependent protein kinase by blocking the cAMP-induced conformational transition

Crystallization of a Deletion Mutant of the R-subunit of cAMP Dependent Protein Kinase

Peptide blockers of PKG inhibit ROS generation by acetylcholine and bradykinin in cardiomyocytes but fail to block protection in the whole heart

Crosstalk between Domains in the Regulatory Subunit of cAMP-Dependent Protein Kinase: Influence of Amino Terminus on cAMP Binding and Holoenzyme Formation

A role for cyclic-GMP dependent protein kinase in anoikis

Inhibition of cGMP-Dependent Protein Kinase Reverses Phenotypic Modulation of Vascular Smooth Muscle Cells

Identifying the molecular switches that determine whether (Rp)-cAMPS functions as an antagonist or an agonist in the activation of cAMP-dependent protein kinase I

The catalytic domain of the cGMP-dependent protein kinase Ialpha modulates the cGMP-binding characteristics of its regulatory domain

Isoleucine 368 is involved in low-affinity binding of N6-modified cAMP analogues to site B of the regulatory subunit of cAMP-dependent protein kinase I

Highly specific, membrane-permeant peptide blockers of cGMP-dependent protein kinase Ialpha inhibit NO-induced cerebral dilation

Delineation of selective cyclic GMP-dependent protein kinase Ialpha substrate and inhibitor peptides based on combinatorial peptide libraries on paper

Expression of a chimeric, cGMP-sensitive regulatory subunit of the cAMP-dependent protein kinase type I alpha

Identification of the amino acid sequences responsible for high affinity activation of cGMP kinase Ialpha

Ala335 is essential for high‐affinity cAMP‐binding of both sites A and B of cAMP‐dependent protein kinase type I

Culture conditions influence uptake and intracellular localization of the membrane permeable cGMP-dependent protein kinase inhibitor DT-2

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