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Clinical validation of the novel fluorescent glomerular filtration rate tracer agent relmapirazin (MB-102)

Kidney international, 2024-10, Vol.106 (4), p.679-687

2024

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Absence of developmental or reproductive toxicity in rats for MB-102, a fluorescent tracer agent for point-of-care measurement of glomerular filtration rate

Regulatory toxicology and pharmacology, 2022-06, Vol.131, p.105158-105158, Article 105158

2022

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Next tier in vitro and in vivo nonclinical studies further elucidating the safety and toxicity profile of MB-102, a novel fluorescent tracer agent for measurement of glomerular filtration rate

Regulatory toxicology and pharmacology, 2019-10, Vol.107, p.104417, Article 104417

2019

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Poly(ethylene oxide)-block-polyphosphester-based paclitaxel conjugates as a platform for ultra-high paclitaxel-loaded multifunctional nanoparticles

Chemical science (Cambridge), 2013-01, Vol.4 (5), p.2122

2013

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Evaluation of Developmental and Reproductive Toxicity in Rabbits for MB-102, a Fluorescent Tracer Agent Designed for Real-Time Measurement of Glomerular Filtration Rate

International journal of toxicology, 2022-09, Vol.41 (5), p.380-388

2022

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Transdermal optical renal function monitoring in humans: development, verification, and validation of a prototype device

Journal of biomedical optics, 2018-05, Vol.23 (5), p.057003-057003

2018

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Characterization of MB-102, a New Fluorescent Tracer Agent for Point-of-Care Renal Function Monitoring

Journal of pharmaceutical sciences, 2020-02, Vol.109 (2), p.1191-1198

2020

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Novel Chiral High-Performance Liquid Chromatographic (HPLC) Determination of MB-102, A New Fluorescent Tracer Agent Enabling the Measurement of Point-of-Care Glomerular Filtration Rate

Analytical letters, 2023-03, Vol.56 (5), p.781-788

2023

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Pre-clinical toxicity evaluation of MB-102, a novel fluorescent tracer agent for real-time measurement of glomerular filtration rate

Regulatory toxicology and pharmacology, 2015-06, Vol.72 (1), p.26-38

2015

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Effectiveness of MB-102, a novel fluorescent tracer agent, for conducting ocular angiography in dogs

American journal of veterinary research, 2020-05, Vol.81 (5), p.428-436

2020

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Adsorption and Clearance of the Novel Fluorescent Tracer Agent MB-102 During Continuous Renal Replacement Therapy: In Vitro Results

ASAIO journal (1992), 2023-07, Vol.69 (7), p.702-707

2023

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Transdermal Detection of MB-102 and Correlation to Meropenem Pharmacokinetics During Continuous Renal Replacement Therapy: In Vivo Results

ASAIO journal (1992), 2023-07, Vol.69 (7), p.708-715

2023

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In Vitro Efficacy of Paclitaxel-Loaded Dual-Responsive Shell Cross-Linked Polymer Nanoparticles Having Orthogonally Degradable Disulfide Cross-Linked Corona and Polyester Core Domains

Molecular pharmaceutics, 2013-03, Vol.10 (3), p.1092-1099

2013

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Mini review of ultrafast fluorescence polarization spectroscopy [invited]

Applied optics. Optical technology and biomedical optics, 2013-02, Vol.52 (5), p.917

2013

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Multicompartment Polymer Nanostructures with Ratiometric Dual-Emission pH-Sensitivity

Journal of the American Chemical Society, 2011-06, Vol.133 (22), p.8534-8543

2011

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Potential Value of Near Real-Time Transdermal GFR Measurement: Estimated GFR Results by CKD-EPI Serum Creatinine Misclassifies CKD Stage in One of Three Adults: TH-PO1038

Journal of the American Society of Nephrology, 2023-11, Vol.34 (11S), p.382-383

2023

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Tuning core vs. shell dimensions to adjust the performance of nanoscopic containers for the loading and release of doxorubicin

Journal of controlled release, 2011-05, Vol.152 (1), p.37-48

2011

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Synergistic Effects of Light-Emitting Probes and Peptides for Targeting and Monitoring Integrin Expression

Proceedings of the National Academy of Sciences - PNAS, 2005-05, Vol.102 (22), p.7976-7981

2005

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First-in-Human Assessment of Gut Permeability in Crohn’s Disease Patients Using Fluorophore Technology

Gastro hep advances, 2024, Vol.3 (4), p.491-497

2024

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Measurement of gut permeability using fluorescent tracer agent technology

Scientific reports, 2017-09, Vol.7 (1), p.10888-8, Article 10888

2017

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Transdermal fluorescence detection of a dual fluorophore system for noninvasive point-of-care gastrointestinal permeability measurement

Biomedical optics express, 2019-10, Vol.10 (10), p.5103-5116

2019

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Hydrophilic Pyrazine Dyes as Exogenous Fluorescent Tracer Agents for Real-Time Point-of-Care Measurement of Glomerular Filtration Rate

Journal of medicinal chemistry, 2011-07, Vol.54 (14), p.5048-5058

2011

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Clinical analysis and quantitation of MB-102, a novel fluorescence tracer agent, in human plasma

Analytical methods, 2018-01, Vol.10 (20), p.2376-2383

2018

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Exogenous fluorescent tracer agents based on pegylated pyrazine dyes for real-time point-of-care measurement of glomerular filtration rate

Bioorganic & medicinal chemistry, 2012-04, Vol.20 (8), p.2490-2497

2012

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Paclitaxel-Loaded SCK Nanoparticles: An Investigation of Loading Capacity and Cell Killing Abilities in Vitro

Molecular pharmaceutics, 2012-08, Vol.9 (8), p.2248-2255

2012

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Clinical validation of the novel fluorescent glomerular filtration rate tracer agent relmapirazin (MB-102)

Absence of developmental or reproductive toxicity in rats for MB-102, a fluorescent tracer agent for point-of-care measurement of glomerular filtration rate

Next tier in vitro and in vivo nonclinical studies further elucidating the safety and toxicity profile of MB-102, a novel fluorescent tracer agent for measurement of glomerular filtration rate

Poly(ethylene oxide)-block-polyphosphester-based paclitaxel conjugates as a platform for ultra-high paclitaxel-loaded multifunctional nanoparticles

Evaluation of Developmental and Reproductive Toxicity in Rabbits for MB-102, a Fluorescent Tracer Agent Designed for Real-Time Measurement of Glomerular Filtration Rate

Transdermal optical renal function monitoring in humans: development, verification, and validation of a prototype device

Characterization of MB-102, a New Fluorescent Tracer Agent for Point-of-Care Renal Function Monitoring

Novel Chiral High-Performance Liquid Chromatographic (HPLC) Determination of MB-102, A New Fluorescent Tracer Agent Enabling the Measurement of Point-of-Care Glomerular Filtration Rate

Pre-clinical toxicity evaluation of MB-102, a novel fluorescent tracer agent for real-time measurement of glomerular filtration rate

Effectiveness of MB-102, a novel fluorescent tracer agent, for conducting ocular angiography in dogs

Adsorption and Clearance of the Novel Fluorescent Tracer Agent MB-102 During Continuous Renal Replacement Therapy: In Vitro Results

Transdermal Detection of MB-102 and Correlation to Meropenem Pharmacokinetics During Continuous Renal Replacement Therapy: In Vivo Results

In Vitro Efficacy of Paclitaxel-Loaded Dual-Responsive Shell Cross-Linked Polymer Nanoparticles Having Orthogonally Degradable Disulfide Cross-Linked Corona and Polyester Core Domains

Mini review of ultrafast fluorescence polarization spectroscopy [invited]

Multicompartment Polymer Nanostructures with Ratiometric Dual-Emission pH-Sensitivity

Potential Value of Near Real-Time Transdermal GFR Measurement: Estimated GFR Results by CKD-EPI Serum Creatinine Misclassifies CKD Stage in One of Three Adults: TH-PO1038

Tuning core vs. shell dimensions to adjust the performance of nanoscopic containers for the loading and release of doxorubicin

Synergistic Effects of Light-Emitting Probes and Peptides for Targeting and Monitoring Integrin Expression

First-in-Human Assessment of Gut Permeability in Crohn’s Disease Patients Using Fluorophore Technology

Measurement of gut permeability using fluorescent tracer agent technology

Transdermal fluorescence detection of a dual fluorophore system for noninvasive point-of-care gastrointestinal permeability measurement

Hydrophilic Pyrazine Dyes as Exogenous Fluorescent Tracer Agents for Real-Time Point-of-Care Measurement of Glomerular Filtration Rate

Clinical analysis and quantitation of MB-102, a novel fluorescence tracer agent, in human plasma

Exogenous fluorescent tracer agents based on pegylated pyrazine dyes for real-time point-of-care measurement of glomerular filtration rate

Paclitaxel-Loaded SCK Nanoparticles: An Investigation of Loading Capacity and Cell Killing Abilities in Vitro

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