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A comprehensive analysis of auditory event‐related potentials and network oscillations in an NMDA receptor antagonist mouse model using a novel wireless recording technology

Physiological reports, 2018-08, Vol.6 (16), p.e13782-n/a

2018

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Age-related synaptic dysfunction in Tg2576 mice starts as a failure in early long-term potentiation which develops into a full abolishment of late long-term potentiation

Journal of neuroscience research, 2016-03, Vol.94 (3), p.266-281

2016

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Targeting the dopamine D1 receptor or its downstream signalling by inhibiting phosphodiesterase‐1 improves cognitive performance

British journal of pharmacology, 2018-07, Vol.175 (14), p.3021-3033

2018

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Targeting the dopamine D 1 receptor or its downstream signalling by inhibiting phosphodiesterase-1 improves cognitive performance

British journal of pharmacology, 2018-07, Vol.175 (14), p.3021-3033

2018

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Symptomatic and preventive effects of the novel phosphodiesterase-9 inhibitor BI 409306 in an immune-mediated model of neurodevelopmental disorders

Neuropsychopharmacology (New York, N.Y.), 2021-07, Vol.46 (8), p.1526-1534

2021

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CRISPR/Cas9-mediated Knockout of the Neuropsychiatric Risk Gene KCTD13 Causes Developmental Deficits in Human Cortical Neurons Derived from Induced Pluripotent Stem Cells

Molecular neurobiology, 2020-02, Vol.57 (2), p.616-634

2020

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Proteomic analysis reveals a biosignature of decreased synaptic protein in cerebrospinal fluid of major depressive disorder

Translational psychiatry, 2020-05, Vol.10 (1), p.144-144, Article 144

2020

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Evaluation of Pharmacokinetics and Pharmacodynamics of BI 425809, a Novel GlyT1 Inhibitor: Translational Studies

Clinical and translational science, 2018-11, Vol.11 (6), p.616-623

2018

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PDE9 INHIBITION IMPROVES COGNITION IN MICE BY A MECHANISM DIFFERENT FROM THE ACETYLCHOLINE ESTERASE INHIBITOR DONEPEZIL

Alzheimer's & dementia, 2017-07, Vol.13 (7), p.P945-P945

2017

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Optimization of touchscreen-based behavioral paradigms in mice: implications for building a battery of tasks taxing learning and memory functions

PloS one, 2014-06, Vol.9 (6), p.e100817

2014

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The Glycine Transport Inhibitor Bi 425809 Restores Translatable EEG Deficits in an Acute Mouse Model for Schizophrenia-Related Sensory Processing and Cortical Network Dysfunction

Biological psychiatry (1969), 2021-05, Vol.89 (9), p.S199-S200

2021

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SA11. Analysis of Auditory Event-Related Potentials and Oscillation in a Mouse Model Related to Schizophrenia by a Novel Technology for Wireless Recording

Schizophrenia bulletin, 2017-03, Vol.43 (suppl_1), p.S116-S117

2017

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P376. Preclinical Pharmacological Characterization of the Selective NR2b Negative Allosteric Modulator BI 1569912 With Potential to Treat MDD

Biological psychiatry (1969), 2022-05, Vol.91 (9), p.S239-S239

2022

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Loss-of-function Mutations of CUL3, a High Confidence Gene for Psychiatric Disorders, Lead to Aberrant Neurodevelopment In Human Induced Pluripotent Stem Cells

Neuroscience, 2020-11, Vol.448, p.234-254

2020

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Pro-cognitive effects of the GlyT1 inhibitor Bitopertin in rodents

European journal of pharmacology, 2022-11, Vol.935, p.175306-175306, Article 175306

2022

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Preclinical validation of the micropipette-guided drug administration (MDA) method in the maternal immune activation model of neurodevelopmental disorders

Brain, behavior, and immunity, 2020-08, Vol.88, p.461-470

2020

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Differential effects of traxoprodil and S-ketamine on quantitative EEG and auditory event-related potentials as translational biomarkers in preclinical trials in rats and mice

Neuropharmacology, 2020-07, Vol.171, p.108072-108072, Article 108072

2020

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Effects of mGlu2/3 Receptor Activation on Neural Network and Single Neuron Function in a Prefrontal Cortex Optogenetic Model of E/I Imbalance

Biological psychiatry (1969), 2020-05, Vol.87 (9), p.S280-S281

2020

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T178. MICROPIPETTE-GUIDED DRUG ADMINISTRATION (MDA) METHOD AS A NOVEL PHARMACOLOGICAL TREATMENT METHOD IN MICE: PRECLINICAL VALIDATION USING RISPERIDONE IN THE MATERNAL IMMUNE ACTIVATION MODEL OF NEURODEVELOPMENTAL DISORDERS

Schizophrenia bulletin, 2020-05, Vol.46 (Supplement_1), p.S299-S299

2020

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M181. DEVELOPMENTAL PROGRESSION OF INTERNEURON NETWORK DEFICITS IN A 15Q13.3 MICRODELETION MOUSE MODEL – A GLIMPSE ON ADOLESCENT PRIMING FOR SCHIZOPHRENIA?

Schizophrenia bulletin, 2020-05, Vol.46 (Supplement_1), p.S205-S205

2020

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S31. ENHANCEMENT OF SYNAPTIC PLASTICITY BY COMBINATION OF PDE2 AND PDE9 INHIBITION PRESUMABLY VIA PRE- AND POST-SYNAPTIC MECHANISMS

Schizophrenia bulletin, 2020-05, Vol.46 (Supplement_1), p.S43-S43

2020

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656. Different Effects of NR2B Antagonists on Behavior Paradigms in Mice

Biological psychiatry (1969), 2017-05, Vol.81 (10), p.S265-S266

2017

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655. Assessment of Efficacy and Psychotomimetic Effects of Ketamine in the Mouse

Biological psychiatry (1969), 2017-05, Vol.81 (10), p.S265-S265

2017

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S188. The Phosphodiesterase-9 Inhibitor BI 409306 Attenuates Social Interaction and Dopaminergic Deficits in Adult Offspring of poly(I:C)-Based Maternal Immune Activation Neurodevelopmental Mouse Model

Biological psychiatry (1969), 2019-05, Vol.85 (10), p.S369-S370

2019

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Different Effects of NR2B Antagonists on Behavior Paradigms in Mice

Biological psychiatry (1969), 2017, Vol.81 (10), p.S265-S266

2017

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A comprehensive analysis of auditory event‐related potentials and network oscillations in an NMDA receptor antagonist mouse model using a novel wireless recording technology

Age-related synaptic dysfunction in Tg2576 mice starts as a failure in early long-term potentiation which develops into a full abolishment of late long-term potentiation

Targeting the dopamine D1 receptor or its downstream signalling by inhibiting phosphodiesterase‐1 improves cognitive performance

Targeting the dopamine D 1 receptor or its downstream signalling by inhibiting phosphodiesterase-1 improves cognitive performance

Symptomatic and preventive effects of the novel phosphodiesterase-9 inhibitor BI 409306 in an immune-mediated model of neurodevelopmental disorders

CRISPR/Cas9-mediated Knockout of the Neuropsychiatric Risk Gene KCTD13 Causes Developmental Deficits in Human Cortical Neurons Derived from Induced Pluripotent Stem Cells

Proteomic analysis reveals a biosignature of decreased synaptic protein in cerebrospinal fluid of major depressive disorder

Evaluation of Pharmacokinetics and Pharmacodynamics of BI 425809, a Novel GlyT1 Inhibitor: Translational Studies

PDE9 INHIBITION IMPROVES COGNITION IN MICE BY A MECHANISM DIFFERENT FROM THE ACETYLCHOLINE ESTERASE INHIBITOR DONEPEZIL

Optimization of touchscreen-based behavioral paradigms in mice: implications for building a battery of tasks taxing learning and memory functions

The Glycine Transport Inhibitor Bi 425809 Restores Translatable EEG Deficits in an Acute Mouse Model for Schizophrenia-Related Sensory Processing and Cortical Network Dysfunction

SA11. Analysis of Auditory Event-Related Potentials and Oscillation in a Mouse Model Related to Schizophrenia by a Novel Technology for Wireless Recording

P376. Preclinical Pharmacological Characterization of the Selective NR2b Negative Allosteric Modulator BI 1569912 With Potential to Treat MDD

Loss-of-function Mutations of CUL3, a High Confidence Gene for Psychiatric Disorders, Lead to Aberrant Neurodevelopment In Human Induced Pluripotent Stem Cells

Pro-cognitive effects of the GlyT1 inhibitor Bitopertin in rodents

Preclinical validation of the micropipette-guided drug administration (MDA) method in the maternal immune activation model of neurodevelopmental disorders

Differential effects of traxoprodil and S-ketamine on quantitative EEG and auditory event-related potentials as translational biomarkers in preclinical trials in rats and mice

Effects of mGlu2/3 Receptor Activation on Neural Network and Single Neuron Function in a Prefrontal Cortex Optogenetic Model of E/I Imbalance

T178. MICROPIPETTE-GUIDED DRUG ADMINISTRATION (MDA) METHOD AS A NOVEL PHARMACOLOGICAL TREATMENT METHOD IN MICE: PRECLINICAL VALIDATION USING RISPERIDONE IN THE MATERNAL IMMUNE ACTIVATION MODEL OF NEURODEVELOPMENTAL DISORDERS

M181. DEVELOPMENTAL PROGRESSION OF INTERNEURON NETWORK DEFICITS IN A 15Q13.3 MICRODELETION MOUSE MODEL – A GLIMPSE ON ADOLESCENT PRIMING FOR SCHIZOPHRENIA?

S31. ENHANCEMENT OF SYNAPTIC PLASTICITY BY COMBINATION OF PDE2 AND PDE9 INHIBITION PRESUMABLY VIA PRE- AND POST-SYNAPTIC MECHANISMS

656. Different Effects of NR2B Antagonists on Behavior Paradigms in Mice

655. Assessment of Efficacy and Psychotomimetic Effects of Ketamine in the Mouse

S188. The Phosphodiesterase-9 Inhibitor BI 409306 Attenuates Social Interaction and Dopaminergic Deficits in Adult Offspring of poly(I:C)-Based Maternal Immune Activation Neurodevelopmental Mouse Model

Different Effects of NR2B Antagonists on Behavior Paradigms in Mice

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