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Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis

Journal of antimicrobial chemotherapy, 2012-11, Vol.67 (11), p.2576-2597

2012

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The use of microtracers in food‐effect trials: An alternative study design for toxic drugs with long half‐lives exemplified by the case for alectinib

Clinical and translational science, 2023-12, Vol.16 (12), p.2557-2564

2023

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Validation and Clinical Evaluation of a Novel Method To Measure Miltefosine in Leishmaniasis Patients Using Dried Blood Spot Sample Collection

Antimicrobial agents and chemotherapy, 2016-04, Vol.60 (4), p.2081-2089

2016

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A physiologically based pharmacokinetic (PBPK) model to describe organ distribution of 68Ga-DOTATATE in patients without neuroendocrine tumors

EJNMMI research, 2021-08, Vol.11 (1), p.73-73, Article 73

2021

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Volumetric absorptive microsampling (VAMS) as an alternative to conventional dried blood spots in the quantification of miltefosine in dried blood samples

Journal of pharmaceutical and biomedical analysis, 2017-02, Vol.135, p.160-166

2017

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Semi-physiological Enriched Population Pharmacokinetic Modelling to Predict the Effects of Pregnancy on the Pharmacokinetics of Cytotoxic Drugs

Clinical pharmacokinetics, 2023-08, Vol.62 (8), p.1157-1167

2023

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Fludarabine exposure in the conditioning prior to allogeneic hematopoietic cell transplantation predicts outcomes

Blood advances, 2019-07, Vol.3 (14), p.2179-2187

2019

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Population pharmacokinetics of levamisole in children with steroid‐sensitive nephrotic syndrome

British journal of clinical pharmacology, 2015-08, Vol.80 (2), p.242-252

2015

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A Semi-Mechanistic Population Pharmacokinetic/Pharmacodynamic Model of Bortezomib in Pediatric Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

Clinical pharmacokinetics, 2020-02, Vol.59 (2), p.207-216

2020

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Quantification of miltefosine in peripheral blood mononuclear cells by high-performance liquid chromatography-tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2015-08, Vol.998-999, p.57-62

2015

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Failure of Miltefosine in Visceral Leishmaniasis Is Associated With Low Drug Exposure

The Journal of infectious diseases, 2014-07, Vol.210 (1), p.146-153

2014

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Lopinavir/ritonavir significantly influences pharmacokinetic exposure of artemether/lumefantrine in HIV-infected Ugandan adults

Journal of antimicrobial chemotherapy, 2012-05, Vol.67 (5), p.1217-1223

2012

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Translational pharmacokinetic modelling and simulation for the assessment of duration of contraceptive use after treatment with miltefosine

Journal of antimicrobial chemotherapy, 2012-08, Vol.67 (8), p.1996-2004

2012

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Reply to Arya and Agarwal

Clinical infectious diseases, 2013-09, Vol.57 (6), p.917-918

2013

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Commentary: Substandard medicines are the priority for neglected tropical diseases

BMJ (Online), 2012-11, Vol.345 (nov14 1), p.e7518-e7518

2012

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Miltefosine: a new remedy for leishmaniasis

Nederlands tijdschrift voor geneeskunde, 2006-12, Vol.150 (49), p.2697

2006

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Efficacy and Safety of AmBisome in Combination with Sodium Stibogluconate or Miltefosine and Miltefosine Monotherapy for African Visceral Leishmaniasis: Phase II Randomized Trial

PLoS neglected tropical diseases, 2016-09, Vol.10 (9), p.e0004880-e0004880

2016

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Increasing Failure of Miltefosine in the Treatment of Kala-azar in Nepal and the Potential Role of Parasite Drug Resistance, Reinfection, or Noncompliance

Clinical infectious diseases, 2013-06, Vol.56 (11), p.1530-1538

2013

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Failure of miltefosine treatment for visceral leishmaniasis in children and men in South-East Asia

PloS one, 2014-06, Vol.9 (6), p.e100220

2014

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Safety and efficacy of paromomycin/miltefosine/liposomal amphotericin B combinations for the treatment of post-kala-azar dermal leishmaniasis in Sudan: A phase II, open label, randomized, parallel arm study

PLoS neglected tropical diseases, 2023-11, Vol.17 (11), p.e0011780-e0011780

2023

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Systematic Review of Host-Mediated Activity of Miltefosine in Leishmaniasis through Immunomodulation

Antimicrobial agents and chemotherapy, 2019-07, Vol.63 (7)

2019

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Optimal Dosing of Miltefosine in Children and Adults with Visceral Leishmaniasis

Antimicrobial Agents and Chemotherapy, 2012-07, Vol.56 (7), p.3864-3872

2012

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An update on the clinical pharmacology of miltefosine in the treatment of leishmaniasis

International journal of antimicrobial agents, 2022-01, Vol.59 (1), p.106459-106459, Article 106459

2022

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Determining tissue distribution of the oral antileishmanial agent miltefosine: a physiologically-based pharmacokinetic modeling approach

Antimicrobial agents and chemotherapy, 2024-07, Vol.68 (7)

2024

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Influence of Malnutrition on the Pharmacokinetics of Drugs Used in the Treatment of Poverty-Related Diseases: A Systematic Review

Clinical pharmacokinetics, 2021-09, Vol.60 (9), p.1149-1169

2021

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Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis

The use of microtracers in food‐effect trials: An alternative study design for toxic drugs with long half‐lives exemplified by the case for alectinib

Validation and Clinical Evaluation of a Novel Method To Measure Miltefosine in Leishmaniasis Patients Using Dried Blood Spot Sample Collection

A physiologically based pharmacokinetic (PBPK) model to describe organ distribution of 68Ga-DOTATATE in patients without neuroendocrine tumors

Volumetric absorptive microsampling (VAMS) as an alternative to conventional dried blood spots in the quantification of miltefosine in dried blood samples

Semi-physiological Enriched Population Pharmacokinetic Modelling to Predict the Effects of Pregnancy on the Pharmacokinetics of Cytotoxic Drugs

Fludarabine exposure in the conditioning prior to allogeneic hematopoietic cell transplantation predicts outcomes

Population pharmacokinetics of levamisole in children with steroid‐sensitive nephrotic syndrome

A Semi-Mechanistic Population Pharmacokinetic/Pharmacodynamic Model of Bortezomib in Pediatric Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

Quantification of miltefosine in peripheral blood mononuclear cells by high-performance liquid chromatography-tandem mass spectrometry

Failure of Miltefosine in Visceral Leishmaniasis Is Associated With Low Drug Exposure

Lopinavir/ritonavir significantly influences pharmacokinetic exposure of artemether/lumefantrine in HIV-infected Ugandan adults

Translational pharmacokinetic modelling and simulation for the assessment of duration of contraceptive use after treatment with miltefosine

Reply to Arya and Agarwal

Commentary: Substandard medicines are the priority for neglected tropical diseases

Miltefosine: a new remedy for leishmaniasis

Efficacy and Safety of AmBisome in Combination with Sodium Stibogluconate or Miltefosine and Miltefosine Monotherapy for African Visceral Leishmaniasis: Phase II Randomized Trial

Increasing Failure of Miltefosine in the Treatment of Kala-azar in Nepal and the Potential Role of Parasite Drug Resistance, Reinfection, or Noncompliance

Failure of miltefosine treatment for visceral leishmaniasis in children and men in South-East Asia

Safety and efficacy of paromomycin/miltefosine/liposomal amphotericin B combinations for the treatment of post-kala-azar dermal leishmaniasis in Sudan: A phase II, open label, randomized, parallel arm study

Systematic Review of Host-Mediated Activity of Miltefosine in Leishmaniasis through Immunomodulation

Optimal Dosing of Miltefosine in Children and Adults with Visceral Leishmaniasis

An update on the clinical pharmacology of miltefosine in the treatment of leishmaniasis

Determining tissue distribution of the oral antileishmanial agent miltefosine: a physiologically-based pharmacokinetic modeling approach

Influence of Malnutrition on the Pharmacokinetics of Drugs Used in the Treatment of Poverty-Related Diseases: A Systematic Review

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