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Recent Advances in the Development of Indazole‐based Anticancer Agents

ChemMedChem, 2018-08, Vol.13 (15), p.1490-1507

2018

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PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy

Frontiers in pharmacology, 2021-05, Vol.12, p.692574-692574

2021

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Protein degradation technology: a strategic paradigm shift in drug discovery

Journal of hematology and oncology, 2021-09, Vol.14 (1), p.138-138, Article 138

2021

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Metabolomic screening of radioiodine refractory thyroid cancer patients and the underlying chemical mechanism of iodine resistance

Scientific reports, 2024-05, Vol.14 (1), p.10546-10546, Article 10546

2024

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Cytotoxicity of Synthesized 1,4-Naphthoquinone Oxime Derivatives on Selected Human Cancer Cell Lines

Chemical and Pharmaceutical Bulletin, 2018/06/01, Vol.66(6), pp.612-619

2018

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Dual inhibition of MYC and SLC39A10 by a novel natural product STAT3 inhibitor derived from Chaetomium globosum suppresses tumor growth and metastasis in gastric cancer

Pharmacological research, 2023-03, Vol.189, p.106703-106703, Article 106703

2023

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Integrative proteomic characterization of adenocarcinoma of esophagogastric junction

Nature communications, 2023-02, Vol.14 (1), p.778-778, Article 778

2023

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A benzochalcone derivative synchronously induces apoptosis and ferroptosis in pancreatic cancer cells

PeerJ (San Francisco, CA), 2023-11, Vol.11, p.e16291-e16291, Article e16291

2023

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Discovery of benzochalcone derivative as a potential antigastric cancer agent targeting signal transducer and activator of transcription 3 (STAT3)

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.2004-2016

2022

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The Chemistry and Biological Effects of Thioflavones

Mini reviews in medicinal chemistry, 2018-01, Vol.18 (20), p.1714

2018

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Biphenyl derivatives incorporating urea unit as novel VEGFR-2 inhibitors: Design, synthesis and biological evaluation

Bioorganic & medicinal chemistry, 2014-01, Vol.22 (1), p.277-284

2014

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Platycodin-D exerts its anti-cancer effect by promoting c-Myc protein ubiquitination and degradation in gastric cancer

Frontiers in pharmacology, 2023-03, Vol.14, p.1138658-1138658

2023

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Design, synthesis, and biological characterization of a potent STAT3 degrader for the treatment of gastric cancer

Frontiers in pharmacology, 2022-08, Vol.13, p.944455-944455

2022

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Chebulagic acid suppresses gastric cancer by inhibiting the AURKA/β-catenin/Wnt pathway

Frontiers in pharmacology, 2023-03, Vol.14, p.1143427-1143427

2023

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Synthesis of 4,8-dimethoxy-1-naphthol via an acetyl migration

Synthetic communications, 2017-03, Vol.47 (6), p.536-540

2017

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Discovery of novel Bcr–Abl inhibitors targeting myristoyl pocket and ATP site

Bioorganic & medicinal chemistry, 2014-12, Vol.22 (24), p.6876-6884

2014

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Competition for electrons between reductive dechlorination and denitrification

Frontiers of environmental science & engineering, 2017-12, Vol.11 (6), p.129-138, Article 14

2017

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Recent Update on Development of Small-Molecule STAT3 Inhibitors for Cancer Therapy: From Phosphorylation Inhibition to Protein Degradation

Journal of medicinal chemistry, 2021-07, Vol.64 (13), p.8884-8915

2021

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Small molecule inhibitors targeting heat shock protein 90: An updated review

European journal of medicinal chemistry, 2024-09, Vol.275, p.116562, Article 116562

2024

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Synthesis and structure-activity relationship studies of α-naphthoflavone derivatives as CYP1B1 inhibitors

European journal of medicinal chemistry, 2020-02, Vol.187, p.111938, Article 111938

2020

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Medicinal chemistry strategies to discover P-glycoprotein inhibitors: An update

Drug resistance updates, 2020-03, Vol.49, p.100681-100681, Article 100681

2020

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Strategies to overcome cancer multidrug resistance (MDR) through targeting P-glycoprotein (ABCB1): An updated review

Pharmacology & therapeutics (Oxford), 2023-09, Vol.249, p.108488-108488, Article 108488

2023

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Discovery of heterocycle-containing α-naphthoflavone derivatives as water-soluble, highly potent and selective CYP1B1 inhibitors

European journal of medicinal chemistry, 2021-01, Vol.209, p.112895-112895, Article 112895

2021

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Design and synthesis of proteolysis-targeting chimeras (PROTACs) as degraders of glutathione peroxidase 4

Bioorganic & medicinal chemistry, 2023-07, Vol.90, p.117352-117352, Article 117352

2023

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ML162 derivatives incorporating a naphthoquinone unit as ferroptosis/apoptosis inducers: Design, synthesis, anti-cancer activity, and drug-resistance reversal evaluation

European journal of medicinal chemistry, 2024-04, Vol.270, p.116387-116387, Article 116387

2024

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Recent Advances in the Development of Indazole‐based Anticancer Agents

PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy

Protein degradation technology: a strategic paradigm shift in drug discovery

Metabolomic screening of radioiodine refractory thyroid cancer patients and the underlying chemical mechanism of iodine resistance

Cytotoxicity of Synthesized 1,4-Naphthoquinone Oxime Derivatives on Selected Human Cancer Cell Lines

Dual inhibition of MYC and SLC39A10 by a novel natural product STAT3 inhibitor derived from Chaetomium globosum suppresses tumor growth and metastasis in gastric cancer

Integrative proteomic characterization of adenocarcinoma of esophagogastric junction

A benzochalcone derivative synchronously induces apoptosis and ferroptosis in pancreatic cancer cells

Discovery of benzochalcone derivative as a potential antigastric cancer agent targeting signal transducer and activator of transcription 3 (STAT3)

The Chemistry and Biological Effects of Thioflavones

Biphenyl derivatives incorporating urea unit as novel VEGFR-2 inhibitors: Design, synthesis and biological evaluation

Platycodin-D exerts its anti-cancer effect by promoting c-Myc protein ubiquitination and degradation in gastric cancer

Design, synthesis, and biological characterization of a potent STAT3 degrader for the treatment of gastric cancer

Chebulagic acid suppresses gastric cancer by inhibiting the AURKA/β-catenin/Wnt pathway

Synthesis of 4,8-dimethoxy-1-naphthol via an acetyl migration

Discovery of novel Bcr–Abl inhibitors targeting myristoyl pocket and ATP site

Competition for electrons between reductive dechlorination and denitrification

Recent Update on Development of Small-Molecule STAT3 Inhibitors for Cancer Therapy: From Phosphorylation Inhibition to Protein Degradation

Small molecule inhibitors targeting heat shock protein 90: An updated review

Synthesis and structure-activity relationship studies of α-naphthoflavone derivatives as CYP1B1 inhibitors

Medicinal chemistry strategies to discover P-glycoprotein inhibitors: An update

Strategies to overcome cancer multidrug resistance (MDR) through targeting P-glycoprotein (ABCB1): An updated review

Discovery of heterocycle-containing α-naphthoflavone derivatives as water-soluble, highly potent and selective CYP1B1 inhibitors

Design and synthesis of proteolysis-targeting chimeras (PROTACs) as degraders of glutathione peroxidase 4

ML162 derivatives incorporating a naphthoquinone unit as ferroptosis/apoptosis inducers: Design, synthesis, anti-cancer activity, and drug-resistance reversal evaluation

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