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Challenges in Drug Development Posed by the COVID‐19 Pandemic: An Opportunity for Clinical Pharmacology

Clinical pharmacology and therapeutics, 2020-10, Vol.108 (4), p.699-702

2020

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A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects

Cell metabolism, 2016-03, Vol.23 (3), p.427-440

2016

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Pharmacokinetics and pharmacodynamics of PF‐05231023, a novel long‐acting FGF21 mimetic, in a first‐in‐human study

British journal of clinical pharmacology, 2015-11, Vol.80 (5), p.1051-1063

2015

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Applying Modeling and Simulations for Rational Dose Selection of Novel Toll‐Like Receptor 7/8 Inhibitor Enpatoran for Indications of High Medical Need

Clinical pharmacology and therapeutics, 2022-08, Vol.112 (2), p.297-306

2022

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Once‐weekly administration of a long‐acting fibroblast growth factor 21 analogue modulates lipids, bone turnover markers, blood pressure and body weight differently in obese people with hypertriglyceridaemia and in non‐human primates

Diabetes, obesity & metabolism, 2017-12, Vol.19 (12), p.1762-1772

2017

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Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis

Proceedings of the National Academy of Sciences - PNAS, 2010-05, Vol.107 (21), p.9771-9776

2010

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Implementation of whole-exome sequencing for pharmacogenomics profiling and exploring its potential clinical utilities

Pharmacogenomics, 2024-03, Vol.25 (4), p.197-206

2024

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Alternatives to rifampicin: A review and perspectives on the choice of strong CYP3A inducers for clinical drug–drug interaction studies

Clinical and translational science, 2022-09, Vol.15 (9), p.2075-2095

2022

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Preparation of megabase-sized DNA from a variety of organisms using the nuclei method for advanced genomics research

Nature protocols, 2012-03, Vol.7 (3), p.467-478

2012

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Risk assessment of drug–drug interaction potential for bintrafusp alfa with cytochrome P4503A4 substrates: A totality of evidence approach

Clinical and translational science, 2022-12, Vol.15 (12), p.2838-2843

2022

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Multi-platform next-generation sequencing of the domestic turkey (Meleagris gallopavo): genome assembly and analysis

PLoS biology, 2010-09, Vol.8 (9), p.e1000475

2010

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Alteration of lipid metabolism in cells infected with human cytomegalovirus

Virology (New York, N.Y.), 2010-08, Vol.404 (1), p.71-77

2010

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Pharmacokinetics/pharmacodynamics model-supported early drug development

Current pharmaceutical biotechnology, 2012-06, Vol.13 (7), p.1360-1375

2012

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Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome

Drug metabolism and disposition, 2017-05, Vol.45 (5), p.501-511

2017

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Quantitative Prediction of Human Pharmacokinetics for Monoclonal Antibodies: Retrospective Analysis of Monkey as a Single Species for First-in-Human Prediction

Clinical pharmacokinetics, 2011-02, Vol.50 (2), p.131-142

2011

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Immunogenicity of avelumab in patients with metastatic Merkel cell carcinoma or advanced urothelial carcinoma

Clinical and translational science, 2024-03, Vol.17 (3), p.e13730-n/a

2024

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Pharmacokinetics and Disposition of the Thiouracil Derivative PF-06282999, an Orally Bioavailable, Irreversible Inactivator of Myeloperoxidase Enzyme, Across Animals and Humans

Drug metabolism and disposition, 2016-02, Vol.44 (2), p.209-219

2016

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Glucuronidation and covalent protein binding of benoxaprofen and flunoxaprofen in sandwich-cultured rat and human hepatocytes

Drug metabolism and disposition, 2009-12, Vol.37 (12), p.2314-2322

2009

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A comparative physical map reveals the pattern of chromosomal evolution between the turkey (Meleagris gallopavo) and chicken (Gallus gallus) genomes

BMC genomics, 2011-09, Vol.12 (1), p.447-447, Article 447

2011

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A BAC/BIBAC-based physical map of chickpea, Cicer arietinum L

BMC genomics, 2010-09, Vol.11 (1), p.501-501, Article 501

2010

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Evobrutinib, a covalent Bruton’s tyrosine kinase inhibitor: Mass balance, elimination route, and metabolism in healthy participants

Clinical and translational science, 2021-11, Vol.14 (6), p.2420-2430

2021

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Phase 1b study of berzosertib and cisplatin in patients with advanced triple-negative breast cancer

NPJ breast cancer, 2022-04, Vol.8 (1), p.45-9, Article 45

2022

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Construction of BIBAC and BAC libraries from a variety of organisms for advanced genomics research

Nature protocols, 2012-03, Vol.7 (3), p.479-499

2012

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Corrigendum to “Alteration of lipid metabolism in cells infected with human cytomegalovirus” [Virology 404 (2010) 71–77]

Virology (New York, N.Y.), 2010, Vol.406 (1), p.164-164

2010

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Challenges in Drug Development Posed by the COVID‐19 Pandemic: An Opportunity for Clinical Pharmacology

A Long-Acting FGF21 Molecule, PF-05231023, Decreases Body Weight and Improves Lipid Profile in Non-human Primates and Type 2 Diabetic Subjects

Pharmacokinetics and pharmacodynamics of PF‐05231023, a novel long‐acting FGF21 mimetic, in a first‐in‐human study

Applying Modeling and Simulations for Rational Dose Selection of Novel Toll‐Like Receptor 7/8 Inhibitor Enpatoran for Indications of High Medical Need

Once‐weekly administration of a long‐acting fibroblast growth factor 21 analogue modulates lipids, bone turnover markers, blood pressure and body weight differently in obese people with hypertriglyceridaemia and in non‐human primates

Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis

Implementation of whole-exome sequencing for pharmacogenomics profiling and exploring its potential clinical utilities

Alternatives to rifampicin: A review and perspectives on the choice of strong CYP3A inducers for clinical drug–drug interaction studies

Preparation of megabase-sized DNA from a variety of organisms using the nuclei method for advanced genomics research

Risk assessment of drug–drug interaction potential for bintrafusp alfa with cytochrome P4503A4 substrates: A totality of evidence approach

Multi-platform next-generation sequencing of the domestic turkey (Meleagris gallopavo): genome assembly and analysis

Alteration of lipid metabolism in cells infected with human cytomegalovirus

Pharmacokinetics/pharmacodynamics model-supported early drug development

Examination of the Human Cytochrome P4503A4 Induction Potential of PF-06282999, an Irreversible Myeloperoxidase Inactivator: Integration of Preclinical, In Silico, and Biomarker Methodologies in the Prediction of the Clinical Outcome

Quantitative Prediction of Human Pharmacokinetics for Monoclonal Antibodies: Retrospective Analysis of Monkey as a Single Species for First-in-Human Prediction

Standardized Mixed-Meal Tolerance and Arginine Stimulation Tests Provide Reproducible and Complementary Measures of β-Cell Function: Results From the Foundation for the National Institutes of Health Biomarkers Consortium Investigative Series

Immunogenicity of avelumab in patients with metastatic Merkel cell carcinoma or advanced urothelial carcinoma

Pharmacokinetics and Disposition of the Thiouracil Derivative PF-06282999, an Orally Bioavailable, Irreversible Inactivator of Myeloperoxidase Enzyme, Across Animals and Humans

Glucuronidation and covalent protein binding of benoxaprofen and flunoxaprofen in sandwich-cultured rat and human hepatocytes

A comparative physical map reveals the pattern of chromosomal evolution between the turkey (Meleagris gallopavo) and chicken (Gallus gallus) genomes

A BAC/BIBAC-based physical map of chickpea, Cicer arietinum L

Evobrutinib, a covalent Bruton’s tyrosine kinase inhibitor: Mass balance, elimination route, and metabolism in healthy participants

Phase 1b study of berzosertib and cisplatin in patients with advanced triple-negative breast cancer

Construction of BIBAC and BAC libraries from a variety of organisms for advanced genomics research

Corrigendum to “Alteration of lipid metabolism in cells infected with human cytomegalovirus” [Virology 404 (2010) 71–77]

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