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Cellulose ether treatment in vivo generates chronic wasting disease prions with reduced protease resistance and delayed disease progression

Journal of neurochemistry, 2020-03, Vol.152 (6), p.727-740

2020

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Continuous intraventricular infusion of pentosan polysulfate: Clinical trial against prion diseases

Neuropathology, 2009-10, Vol.29 (5), p.632-636

2009

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Insights from Therapeutic Studies for PrP Prion Disease

Cold Spring Harbor perspectives in medicine, 2017-03, Vol.7 (3), p.a024430

2017

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Protease-resistant PrP and PrP oligomers in the brain in human prion diseases after intraventricular pentosan polysulfate infusion

Neuropathology, 2012-04, Vol.32 (2), p.124-132

2012

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Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints

Nucleic acids research, 2020-11, Vol.48 (19), p.10615-10631

2020

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Cellulose ether treatment inhibits amyloid beta aggregation, neuroinflammation and cognitive deficits in transgenic mouse model of Alzheimer's disease

Journal of neuroinflammation, 2023-07, Vol.20 (1), p.177-177, Article 177

2023

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Preparation and Characterization of Cellulose Ether Liposomes for the Inhibition of Prion Formation in Prion-Infected Cells

Journal of pharmaceutical sciences, 2019-08, Vol.108 (8), p.2814-2820

2019

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Decrease in Skin Prion-Seeding Activity of Prion-Infected Mice Treated with a Compound Against Human and Animal Prions: a First Possible Biomarker for Prion Therapeutics

Molecular neurobiology, 2021-09, Vol.58 (9), p.4280-4292

2021

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A Single Subcutaneous Injection of Cellulose Ethers Administered Long before Infection Confers Sustained Protection against Prion Diseases in Rodents

PLoS pathogens, 2016-12, Vol.12 (12), p.e1006045-e1006045

2016

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Intermolecular crosslinking of abnormal prion protein is efficiently induced by a primuline-sensitized photoreaction

Biochimica et biophysica acta. General subjects, 2019-02, Vol.1863 (2), p.384-394

2019

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Amyloid-binding compounds and their anti-prion potency

Current topics in medicinal chemistry, 2013-10, Vol.13 (19), p.2522-2532

2013

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Styrylbenzoazole derivatives for imaging of prion plaques and treatment of transmissible spongiform encephalopathies

Journal of neurochemistry, 2006-10, Vol.99 (1), p.198-205

2006

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Surface Plasmon Resonance Analysis for the Screening of Anti-prion Compounds

Biological and Pharmaceutical Bulletin, 2006, Vol.29(5), pp.927-932

2006

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Pyrene conjugation and spectroscopic analysis of hydroxypropyl methylcellulose compounds successfully demonstrated a local dielectric difference associated with in vivo anti-prion activity

PloS one, 2017-09, Vol.12 (9), p.e0185357-e0185357

2017

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Orally Administered Amyloidophilic Compound Is Effective in Prolonging the Incubation Periods of Animals Cerebrally Infected with Prion Diseases in a Prion Strain-Dependent Manner

Journal of Virology, 2007-12, Vol.81 (23), p.12889-12898

2007

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Combining autophagy stimulators and cellulose ethers for therapy against prion disease

Prion, 2019-01, Vol.13 (1), p.185-196

2019

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Lysosomotropic Agents and Cysteine Protease Inhibitors Inhibit Scrapie-Associated Prion Protein Accumulation

Journal of Virology, 2000-05, Vol.74 (10), p.4894-4897

2000

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Structure–activity analysis and antiprion mechanism of isoprenoid compounds

Virology (New York, N.Y.), 2015-12, Vol.486, p.63-70

2015

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Treatment of Transmissible Spongiform Encephalopathy by Intraventricular Drug Infusion in Animal Models

Journal of Virology, 2004-05, Vol.78 (10), p.4999-5006

2004

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Heparinase I-specific disaccharide unit of heparin is a key structure but insufficient for exerting anti-prion activity in prion-infected cells

Biochemical and biophysical research communications, 2015-05, Vol.460 (4), p.989-995

2015

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Secretin receptor involvement in prion-infected cells and animals

FEBS letters, 2015-07, Vol.589 (15), p.2011-2018

2015

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Chelating compound, chrysoidine, is more effective in both antiprion activity and brain endothelial permeability than quinacrine

Cellular and molecular neurobiology, 2007-05, Vol.27 (3), p.303-316

2007

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Brain stem lesions in sporadic Creutzfeldt-Jakob disease: A histopathological and immunohistochemical study

Neuropathology, 2006-02, Vol.26 (1), p.43-49

2006

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Impairment of microglial responses to facial nerve axotomy in cathepsin S-deficient mice

Journal of neuroscience research, 2007-08, Vol.85 (10), p.2196-2206

2007

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Anti-prion activity of protein-bound polysaccharide K in prion-infected cells and animals

Biochemical and biophysical research communications, 2011-02, Vol.405 (2), p.285-290

2011

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Cellulose ether treatment in vivo generates chronic wasting disease prions with reduced protease resistance and delayed disease progression

Continuous intraventricular infusion of pentosan polysulfate: Clinical trial against prion diseases

Insights from Therapeutic Studies for PrP Prion Disease

Protease-resistant PrP and PrP oligomers in the brain in human prion diseases after intraventricular pentosan polysulfate infusion

Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints

Cellulose ether treatment inhibits amyloid beta aggregation, neuroinflammation and cognitive deficits in transgenic mouse model of Alzheimer's disease

Preparation and Characterization of Cellulose Ether Liposomes for the Inhibition of Prion Formation in Prion-Infected Cells

Decrease in Skin Prion-Seeding Activity of Prion-Infected Mice Treated with a Compound Against Human and Animal Prions: a First Possible Biomarker for Prion Therapeutics

A Single Subcutaneous Injection of Cellulose Ethers Administered Long before Infection Confers Sustained Protection against Prion Diseases in Rodents

Intermolecular crosslinking of abnormal prion protein is efficiently induced by a primuline-sensitized photoreaction

Amyloid-binding compounds and their anti-prion potency

Styrylbenzoazole derivatives for imaging of prion plaques and treatment of transmissible spongiform encephalopathies

Surface Plasmon Resonance Analysis for the Screening of Anti-prion Compounds

Pyrene conjugation and spectroscopic analysis of hydroxypropyl methylcellulose compounds successfully demonstrated a local dielectric difference associated with in vivo anti-prion activity

Orally Administered Amyloidophilic Compound Is Effective in Prolonging the Incubation Periods of Animals Cerebrally Infected with Prion Diseases in a Prion Strain-Dependent Manner

Combining autophagy stimulators and cellulose ethers for therapy against prion disease

Lysosomotropic Agents and Cysteine Protease Inhibitors Inhibit Scrapie-Associated Prion Protein Accumulation

Structure–activity analysis and antiprion mechanism of isoprenoid compounds

Treatment of Transmissible Spongiform Encephalopathy by Intraventricular Drug Infusion in Animal Models

Heparinase I-specific disaccharide unit of heparin is a key structure but insufficient for exerting anti-prion activity in prion-infected cells

Secretin receptor involvement in prion-infected cells and animals

Chelating compound, chrysoidine, is more effective in both antiprion activity and brain endothelial permeability than quinacrine

Brain stem lesions in sporadic Creutzfeldt-Jakob disease: A histopathological and immunohistochemical study

Impairment of microglial responses to facial nerve axotomy in cathepsin S-deficient mice

Anti-prion activity of protein-bound polysaccharide K in prion-infected cells and animals

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