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Synthesis of Simplified Azasordarin Analogs as Potential Antifungal Agents

Journal of organic chemistry, 2019-05, Vol.84 (9), p.5292-5304

2019

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Cytoprotective activated protein C averts Nlrp3 inflammasome–induced ischemia-reperfusion injury via mTORC1 inhibition

Blood, 2017-12, Vol.130 (24), p.2664-2677

2017

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Reversal of the renal hyperglycemic memory in diabetic kidney disease by targeting sustained tubular p21 expression

Nature communications, 2022-08, Vol.13 (1), p.5062-5062, Article 5062

2022

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Monitoring Replication Protein A (RPA) dynamics in homologous recombination through site-specific incorporation of non-canonical amino acids

Nucleic acids research, 2017-09, Vol.45 (16), p.9413-9426

2017

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The Evolving Concept of Neuro-Thromboinflammation for Neurodegenerative Disorders and Neurotrauma: A Rationale for PAR1-Targeting Therapies

Biomolecules (Basel, Switzerland), 2021-10, Vol.11 (11), p.1558

2021

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Synthesis of diverse heterocyclic scaffolds via tandem additions to imine derivatives and ring-forming reactions

Tetrahedron, 2009-09, Vol.65 (33), p.6454-6469

2009

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DFT-assisted design and evaluation of bifunctional copper(I) catalysts for the direct intermolecular addition of aldehydes and ketones to alkynes

Tetrahedron, 2018-09, Vol.74 (37), p.4823-4836

2018

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Multifunctional heterocyclic scaffolds for hybrid Lewis acid/Lewis base catalysis of carbon–carbon bond formation

Tetrahedron, 2016-07, Vol.72 (27-28), p.3905-3916

2016

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Synthesis of a novel bicyclic scaffold inspired by the antifungal natural product sordarin

Tetrahedron letters, 2018-09, Vol.59 (36), p.3373-3376

2018

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Design and Evaluation of Heterobivalent PAR1–PAR2 Ligands as Antagonists of Calcium Mobilization

ACS medicinal chemistry letters, 2019-01, Vol.10 (1), p.121-126

2019

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Characterizing Modulators of Protease-activated Receptors with a Calcium Mobilization Assay Using a Plate Reader

Journal of visualized experiments, 2024-05 (207)

2024

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Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies

ACS medicinal chemistry letters, 2012-10, Vol.3 (10), p.808-813

2012

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DFT-Assisted Design and Evaluation of Bifunctional Amine/Pyridine-Oxazoline Metal Catalysts for Additions of Ketones to Unactivated Alkenes and Alkynes

Synthesis (Stuttgart), 2019-01, Vol.51 (2), p.450-462

2019

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Applications of Multicomponent Reactions for the Synthesis of Diverse Heterocyclic Scaffolds

Organic letters, 2007-10, Vol.9 (21), p.4223-4226

2007

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Modified synthesis of the peptidomimetic natriuretic peptide receptor-C antagonist M372049

Tetrahedron letters, 2020-03, Vol.61 (12), p.151654, Article 151654

2020

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Route exploration and synthesis of the reported pyridone-based PDI inhibitor STK076545

Organic & biomolecular chemistry, 2020-09, Vol.18 (34), p.6665-6681

2020

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PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury

Proceedings of the National Academy of Sciences - PNAS, 2018-01, Vol.115 (5), p.E982-E991

2018

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Computationally‐Guided Investigation of Dual Amine/pi Lewis Acid Catalysts for Direct Additions of Aldehydes and Ketones to Unactivated Alkenes and Alkynes

ChemistrySelect (Weinheim), 2020-07, Vol.5 (28), p.8405-8414

2020

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Hepatocyte-independent PAR1-biased signaling controls liver pathology in experimental obesity

Journal of thrombosis and haemostasis, 2024-11, Vol.22 (11), p.3191-3198

2024

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Palladium(II) Catalyst Systems for the Addition of Boronic Acids to Bicyclic Alkenes: New Scope and Reactivity

Organic letters, 2003-10, Vol.5 (20), p.3695-3698

2003

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NMR Structural Analysis of Isolated Shaker Voltage-Sensing Domain in LPPG Micelles

Biophysical journal, 2019-07, Vol.117 (2), p.388-398

2019

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Rhodium-Catalyzed Asymmetric Ring Opening of Oxabicyclic Alkenes with Organoboronic Acids

Organic letters, 2002-04, Vol.4 (8), p.1311-1314

2002

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Parmodulins inhibit thrombus formation without inducing endothelial injury caused by vorapaxar

Blood, 2015-03, Vol.125 (12), p.1976-1985

2015

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Concise Enantioselective Total Syntheses of (+)-Homochelidonine, (+)-Chelamidine, (+)-Chelidonine, (+)-Chelamine and (+)-Norchelidonine by a PdII-Catalyzed Ring-Opening Strategy

Chemistry : a European journal, 2008-02, Vol.14 (7), p.2112-2124

2008

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An Anthrone-Based Kv7.2/7.3 Channel Blocker with Improved Properties for the Investigation of Psychiatric and Neuro-degenerative Disorders

Bioorganic & medicinal chemistry letters, 2019-09, Vol.29 (23), p.126681-126681

2019

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Synthesis of Simplified Azasordarin Analogs as Potential Antifungal Agents

Cytoprotective activated protein C averts Nlrp3 inflammasome–induced ischemia-reperfusion injury via mTORC1 inhibition

Reversal of the renal hyperglycemic memory in diabetic kidney disease by targeting sustained tubular p21 expression

Monitoring Replication Protein A (RPA) dynamics in homologous recombination through site-specific incorporation of non-canonical amino acids

The Evolving Concept of Neuro-Thromboinflammation for Neurodegenerative Disorders and Neurotrauma: A Rationale for PAR1-Targeting Therapies

Synthesis of diverse heterocyclic scaffolds via tandem additions to imine derivatives and ring-forming reactions

DFT-assisted design and evaluation of bifunctional copper(I) catalysts for the direct intermolecular addition of aldehydes and ketones to alkynes

Multifunctional heterocyclic scaffolds for hybrid Lewis acid/Lewis base catalysis of carbon–carbon bond formation

Synthesis of a novel bicyclic scaffold inspired by the antifungal natural product sordarin

Design and Evaluation of Heterobivalent PAR1–PAR2 Ligands as Antagonists of Calcium Mobilization

Characterizing Modulators of Protease-activated Receptors with a Calcium Mobilization Assay Using a Plate Reader

Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies

DFT-Assisted Design and Evaluation of Bifunctional Amine/Pyridine-Oxazoline Metal Catalysts for Additions of Ketones to Unactivated Alkenes and Alkynes

Applications of Multicomponent Reactions for the Synthesis of Diverse Heterocyclic Scaffolds

Modified synthesis of the peptidomimetic natriuretic peptide receptor-C antagonist M372049

Route exploration and synthesis of the reported pyridone-based PDI inhibitor STK076545

PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury

Computationally‐Guided Investigation of Dual Amine/pi Lewis Acid Catalysts for Direct Additions of Aldehydes and Ketones to Unactivated Alkenes and Alkynes

Hepatocyte-independent PAR1-biased signaling controls liver pathology in experimental obesity

Palladium(II) Catalyst Systems for the Addition of Boronic Acids to Bicyclic Alkenes: New Scope and Reactivity

NMR Structural Analysis of Isolated Shaker Voltage-Sensing Domain in LPPG Micelles

Rhodium-Catalyzed Asymmetric Ring Opening of Oxabicyclic Alkenes with Organoboronic Acids

Parmodulins inhibit thrombus formation without inducing endothelial injury caused by vorapaxar

Concise Enantioselective Total Syntheses of (+)-Homochelidonine, (+)-Chelamidine, (+)-Chelidonine, (+)-Chelamine and (+)-Norchelidonine by a PdII-Catalyzed Ring-Opening Strategy

An Anthrone-Based Kv7.2/7.3 Channel Blocker with Improved Properties for the Investigation of Psychiatric and Neuro-degenerative Disorders

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