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Cellular sheddases are induced by Merkel cell polyomavirus small tumour antigen to mediate cell dissociation and invasiveness

PLoS pathogens, 2018-09, Vol.14 (9), p.e1007276-e1007276

2018

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Identification of potassium and calcium channel inhibitors as modulators of polyomavirus endosomal trafficking

Antiviral research, 2020-07, Vol.179, p.104819-104819, Article 104819

2020

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Merkel cell polyomavirus small tumour antigen activates the p38 MAPK pathway to enhance cellular motility

Biochemical journal, 2020-07, Vol.477 (14), p.2721-2733

2020

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Corrigendum: A highly discriminatory RNA strand-specific assay to facilitate analysis of the role of cis -acting elements in foot-and-mouth disease virus replication

Journal of general virology, 2024-05, Vol.105 (5)

2024

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The dual role of a highly structured RNA (the S fragment) in the replication of foot‐and‐mouth disease virus

The FASEB journal, 2024-07, Vol.38 (14), p.e23822-n/a

2024

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A highly discriminatory RNA strand-specific assay to facilitate analysis of the role of cis -acting elements in foot-and-mouth disease virus replication

Journal of general virology, 2023-07, Vol.104 (7)

2023

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Development of an ELISA to distinguish between foot-and-mouth disease virus infected and vaccinated animals utilising the viral non-structural protein 3ABC

Journal of medical microbiology, 2022-04, Vol.71 (4)

2022

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Development of Enterovirus Antiviral Agents That Target the Viral 2C Protein

ChemMedChem, 2023-05, Vol.18 (10), p.e202200541-n/a

2023

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Merkel Cell Polyomavirus Small T Antigen Drives Cell Motility via Rho-GTPase-Induced Filopodium Formation

Journal of virology, 2018-01, Vol.92 (2)

2018

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Front Cover: Development of Enterovirus Antiviral Agents That Target the Viral 2C Protein (ChemMedChem 10/2023)

ChemMedChem, 2023-05, Vol.18 (10), p.n/a

2023

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Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide

Nature chemistry, 2020-05, Vol.12 (5), p.445-451

2020

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Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (42), p.15072-15077

2014

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The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

Immunity (Cambridge, Mass.), 2013-09, Vol.39 (3), p.443-453

2013

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Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

Cell, 2012-05, Vol.149 (5), p.1048-1059

2012

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Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism

Proceedings of the National Academy of Sciences - PNAS, 2013-06, Vol.110 (24), p.9758-9763

2013

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A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

Nature structural & molecular biology, 2015-03, Vol.22 (3), p.207-213

2015

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From Macroscopic Measurements to Microscopic Mechanisms of Protein Aggregation

Journal of molecular biology, 2012-08, Vol.421 (2-3), p.160-171

2012

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Analytical Solution to the Kinetics of Breakable Filament Assembly

Science (American Association for the Advancement of Science), 2009-12, Vol.326 (5959), p.1533-1537

2009

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Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (26), p.9384-9389

2014

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Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer’s disease

Proceedings of the National Academy of Sciences - PNAS, 2017-01, Vol.114 (2), p.E200-E208

2017

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Microfluidic Diffusion Analysis of the Sizes and Interactions of Proteins under Native Solution Conditions

ACS nano, 2016-01, Vol.10 (1), p.333-341

2016

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Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (16), p.E1994-E2003

2015

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Observation of spatial propagation of amyloid assembly from single nuclei

Proceedings of the National Academy of Sciences - PNAS, 2011-09, Vol.108 (36), p.14746-14751

2011

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Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies

Nature structural & molecular biology, 2020-12, Vol.27 (12), p.1125-1133

2020

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Ostwald's rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers

Nature communications, 2014-11, Vol.5 (1), p.5219-5219, Article 5219

2014

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Cellular sheddases are induced by Merkel cell polyomavirus small tumour antigen to mediate cell dissociation and invasiveness

Identification of potassium and calcium channel inhibitors as modulators of polyomavirus endosomal trafficking

Merkel cell polyomavirus small tumour antigen activates the p38 MAPK pathway to enhance cellular motility

Corrigendum: A highly discriminatory RNA strand-specific assay to facilitate analysis of the role of cis -acting elements in foot-and-mouth disease virus replication

The dual role of a highly structured RNA (the S fragment) in the replication of foot‐and‐mouth disease virus

A highly discriminatory RNA strand-specific assay to facilitate analysis of the role of cis -acting elements in foot-and-mouth disease virus replication

Development of an ELISA to distinguish between foot-and-mouth disease virus infected and vaccinated animals utilising the viral non-structural protein 3ABC

Development of Enterovirus Antiviral Agents That Target the Viral 2C Protein

Merkel Cell Polyomavirus Small T Antigen Drives Cell Motility via Rho-GTPase-Induced Filopodium Formation

Front Cover: Development of Enterovirus Antiviral Agents That Target the Viral 2C Protein (ChemMedChem 10/2023)

Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide

Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism

A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers

From Macroscopic Measurements to Microscopic Mechanisms of Protein Aggregation

Analytical Solution to the Kinetics of Breakable Filament Assembly

Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides

Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer’s disease

Microfluidic Diffusion Analysis of the Sizes and Interactions of Proteins under Native Solution Conditions

Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation

Observation of spatial propagation of amyloid assembly from single nuclei

Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies

Ostwald's rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers

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