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4-Phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione Inhibitors of the Checkpoint Kinase Wee1. Structure−Activity Relationships for Chromophore Modification and Phenyl Ring Substitution

Journal of medicinal chemistry, 2006-08, Vol.49 (16), p.4896-4911

2006

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Specific, Irreversible Inactivation of the Epidermal Growth Factor Receptor and erbB2, by a New Class of Tyrosine Kinase Inhibitor

Proceedings of the National Academy of Sciences - PNAS, 1998-09, Vol.95 (20), p.12022-12027

1998

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Pyrido[2,3-d]pyrimidin-7-ones as Specific Inhibitors of Cyclin-Dependent Kinase 4

Journal of medicinal chemistry, 2005-04, Vol.48 (7), p.2371-2387

2005

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Tyrosine Kinase Inhibitors. 15. 4-(Phenylamino)quinazoline and 4-(Phenylamino)pyrido[d]pyrimidine Acrylamides as Irreversible Inhibitors of the ATP Binding Site of the Epidermal Growth Factor Receptor

Journal of medicinal chemistry, 1999-05, Vol.42 (10), p.1803-1815

1999

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Structure-Based Design of a Potent, Selective, and Irreversible Inhibitor of the Catalytic Domain of the erbB Receptor Subfamily of Protein Tyrosine Kinases

Journal of medicinal chemistry, 1997-03, Vol.40 (7), p.1130-1135

1997

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Substrate Specificity of the Protein Tyrosine Phosphatases

Proceedings of the National Academy of Sciences - PNAS, 1993-05, Vol.90 (10), p.4446-4450

1993

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Structure–activity relationships for 2-anilino-6-phenylpyrido[2,3- d]pyrimidin-7(8 H)-ones as inhibitors of the cellular checkpoint kinase Wee1

Bioorganic & medicinal chemistry letters, 2005-04, Vol.15 (7), p.1931-1935

2005

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Transmission disequilibrium and haplotype analyses of the G72/G30 locus: Suggestive linkage to schizophrenia in Palestinian Arabs living in the North of Israel

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2006-01, Vol.141B (1), p.91-95

2006

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2-Aminoquinazoline inhibitors of cyclin-dependent kinases

Bioorganic & medicinal chemistry letters, 2005-09, Vol.15 (17), p.3881-3885

2005

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Sequence specificity in recognition of the epidermal growth factor receptor by protein tyrosine phosphatase 1B

The Journal of biological chemistry, 1993-11, Vol.268 (31), p.23634-23639

1993

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Family-based and case-control study of catechol-O-methyltransferase in schizophrenia among Palestinian Arabs

American journal of medical genetics. Part B, Neuropsychiatric genetics, 2003-05, Vol.119B (1), p.35-39

2003

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Synthesis and structure–activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4- c]carbazole-1,3(2 H,6 H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases

European journal of medicinal chemistry, 2008-06, Vol.43 (6), p.1276-1296

2008

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Determinants of Substrate Recognition in the Protein-tyrosine Phosphatase, PTP1 (∗)

The Journal of biological chemistry, 1996-03, Vol.271 (10), p.5386-5392

1996

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Tyrosine Kinase Inhibitors. 3. Structure-Activity Relationships for Inhibition of Protein Tyrosine Kinases by Nuclear-Substituted Derivatives of 2,2'-Dithiobis(1-methyl-N-phenyl-1H-indole-3-carboxamide)

Journal of medicinal chemistry, 1994-06, Vol.37 (13), p.2033-2042

1994

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Tyrosine kinase inhibitors. 1. Structure-activity relationships for inhibition of epidermal growth factor receptor tyrosine kinase activity by 2,3-dihydro-2-thioxo-1H-indole-3-alkanoic acids and 2,2'-dithiobis(1H-indole-3-alkanoic acids)

Journal of medicinal chemistry, 1993-08, Vol.36 (17), p.2459-2469

1993

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A family-based study of the Cys23Ser 5HT2C serotonin receptor polymorphism in schizophrenia

American journal of medical genetics, 2001-04, Vol.105 (3), p.236-238

2001

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Parenteral clozapine: five years of experience

Journal of clinical psychopharmacology, 1999-10, Vol.19 (5), p.479-480

1999

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Acute olanzapine overdose

Human psychopharmacology, 1999-07, Vol.14 (5), p.355-356

1999

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No association between the dopamine D3 receptor Bal I polymorphism and schizophrenia in a family-based study of a Palestinian Arab population

American journal of medical genetics, 2000-12, Vol.96 (6), p.778-780

2000

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No evidence for linkage by transmission disequilibrium test analysis of microsatellite marker D22S278 and schizophrenia in a Palestinian Arab and in a German population

American journal of medical genetics, 2001-05, Vol.105 (4), p.328-331

2001

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Attentional Asymmetry in Schizophrenia: Disengagement and Inhibition of Return Deficits

Neuropsychology, 2001-07, Vol.15 (3), p.361-370

2001

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Differentiation of peptide molecular recognition by phospholipase Cγ‐1 Src homology‐2 domain and a mutant Tyr phosphatase PTP1bC215S

Protein science, 1995-01, Vol.4 (1), p.13-20

1995

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Identification of amino acids in the N-terminal SH2 domain of phospholipase C gamma 1 important in the interaction with epidermal growth factor receptor

Biochemistry (Easton), 1994-12, Vol.33 (49), p.14671

1994

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Cerebrospinal fluid inositol monophosphatase: elevated activity in depression and neuroleptic-treated schizophrenia

European neuropsychopharmacology, 1998-11, Vol.8, p.S193-S193

1998

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Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H )diones as inhibitors of Weel and Chkl checkpoint kinases

European journal of medicinal chemistry, 2008, Vol.43 (6), p.1276-1296

2008

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4-Phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione Inhibitors of the Checkpoint Kinase Wee1. Structure−Activity Relationships for Chromophore Modification and Phenyl Ring Substitution

Specific, Irreversible Inactivation of the Epidermal Growth Factor Receptor and erbB2, by a New Class of Tyrosine Kinase Inhibitor

Pyrido[2,3-d]pyrimidin-7-ones as Specific Inhibitors of Cyclin-Dependent Kinase 4

Tyrosine Kinase Inhibitors. 15. 4-(Phenylamino)quinazoline and 4-(Phenylamino)pyrido[d]pyrimidine Acrylamides as Irreversible Inhibitors of the ATP Binding Site of the Epidermal Growth Factor Receptor

Structure-Based Design of a Potent, Selective, and Irreversible Inhibitor of the Catalytic Domain of the erbB Receptor Subfamily of Protein Tyrosine Kinases

Substrate Specificity of the Protein Tyrosine Phosphatases

Structure–activity relationships for 2-anilino-6-phenylpyrido[2,3- d]pyrimidin-7(8 H)-ones as inhibitors of the cellular checkpoint kinase Wee1

Transmission disequilibrium and haplotype analyses of the G72/G30 locus: Suggestive linkage to schizophrenia in Palestinian Arabs living in the North of Israel

2-Aminoquinazoline inhibitors of cyclin-dependent kinases

Sequence specificity in recognition of the epidermal growth factor receptor by protein tyrosine phosphatase 1B

Family-based and case-control study of catechol-O-methyltransferase in schizophrenia among Palestinian Arabs

Synthesis and structure–activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4- c]carbazole-1,3(2 H,6 H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases

Determinants of Substrate Recognition in the Protein-tyrosine Phosphatase, PTP1 (∗)

Tyrosine Kinase Inhibitors. 3. Structure-Activity Relationships for Inhibition of Protein Tyrosine Kinases by Nuclear-Substituted Derivatives of 2,2'-Dithiobis(1-methyl-N-phenyl-1H-indole-3-carboxamide)

Tyrosine kinase inhibitors. 1. Structure-activity relationships for inhibition of epidermal growth factor receptor tyrosine kinase activity by 2,3-dihydro-2-thioxo-1H-indole-3-alkanoic acids and 2,2'-dithiobis(1H-indole-3-alkanoic acids)

A family-based study of the Cys23Ser 5HT2C serotonin receptor polymorphism in schizophrenia

Parenteral clozapine: five years of experience

Acute olanzapine overdose

No association between the dopamine D3 receptor Bal I polymorphism and schizophrenia in a family-based study of a Palestinian Arab population

No evidence for linkage by transmission disequilibrium test analysis of microsatellite marker D22S278 and schizophrenia in a Palestinian Arab and in a German population

Attentional Asymmetry in Schizophrenia: Disengagement and Inhibition of Return Deficits

Differentiation of peptide molecular recognition by phospholipase Cγ‐1 Src homology‐2 domain and a mutant Tyr phosphatase PTP1bC215S

Identification of amino acids in the N-terminal SH2 domain of phospholipase C gamma 1 important in the interaction with epidermal growth factor receptor

Cerebrospinal fluid inositol monophosphatase: elevated activity in depression and neuroleptic-treated schizophrenia

Synthesis and structure-activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H )diones as inhibitors of Weel and Chkl checkpoint kinases

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