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Improvement of conventional anti-cancer drugs as new tools against multidrug resistant tumors

Drug resistance updates, 2020-05, Vol.50, p.100682, Article 100682

2020

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Study of chitosan/xanthan gum polyelectrolyte complexes formation, solid state and influence on ibuprofen release kinetics

International journal of biological macromolecules, 2020-04, Vol.148, p.942-955

2020

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Influence of Solid Drug Delivery System Formulation on Poorly Water-Soluble Drug Dissolution and Permeability

Molecules (Basel, Switzerland), 2015-08, Vol.20 (8), p.14684-14698

2015

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Comparison of the Effect of Bioadhesive Polymers on Stability and Drug Release Kinetics of Biocompatible Hydrogels for Topical Application of Ibuprofen

Journal of pharmaceutical sciences, 2019-03, Vol.108 (3), p.1326-1333

2019

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High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances

International journal of pharmaceutics, 2023-02, Vol.633, p.122613-122613, Article 122613

2023

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Prediction of blood–brain barrier permeation of α-adrenergic and imidazoline receptor ligands using PAMPA technique and quantitative-structure permeability relationship analysis

European journal of pharmaceutical sciences, 2015-02, Vol.68, p.94-105

2015

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Synthesis, Evaluation of Enzyme Inhibition and Redox Properties of Potential Dual COX-2 and 5-LOX Inhibitors

Pharmaceuticals (Basel, Switzerland), 2023-04, Vol.16 (4), p.549

2023

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Synthesis and Investigation of Anti-Inflammatory Activity of New Thiourea Derivatives of Naproxen

Pharmaceuticals (Basel, Switzerland), 2023-04, Vol.16 (5), p.666

2023

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Estimation of passive gastrointestinal absorption of new dual DNA gyrase and topoisomerase IV inhibitors using PAMPA and biopartitioning micellar chromatography and quantitative structure-retention relationship analysis

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2024-06, Vol.1240, p.124158, Article 124158

2024

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Development of solid lipid microparticles by melt-emulsification/spray-drying processes as carriers for pulmonary drug delivery

European journal of pharmaceutical sciences, 2021-01, Vol.156, p.105588-105588, Article 105588

2021

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Evaluation of critical formulation parameters in design and differentiation of self-microemulsifying drug delivery systems (SMEDDSs) for oral delivery of aciclovir

International journal of pharmaceutics, 2016-01, Vol.497 (1-2), p.301-311

2016

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Selectivity of N(2)-substituted oxotriazinoindole aldose reductase inhibitors is determined by the interaction pattern with Pro301-Arg312 loop of aldehyde reductase

Medicinal chemistry research, 2024-03, Vol.33 (3), p.492-503

2024

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Discovery of Novel Thiophene/Hydrazones: In Vitro and In Silico Studies against Pancreatic Cancer

Pharmaceutics, 2023-05, Vol.15 (5), p.1441

2023

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An electrochemical study of 9-chloroacridine redox behavior and its interaction with double-stranded DNA

Bioelectrochemistry (Amsterdam, Netherlands), 2020-10, Vol.135, p.107579, Article 107579

2020

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Square wave voltammetric study of interaction between 9-acridinyl amino acid derivatives and DNA

Bioelectrochemistry (Amsterdam, Netherlands), 2023-02, Vol.149, p.108323-108323, Article 108323

2023

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Effect of ibuprofen entrapment procedure on physicochemical and controlled drug release performances of chitosan/xanthan gum polyelectrolyte complexes

International journal of biological macromolecules, 2021-01, Vol.167, p.547-558

2021

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Unveiling Anticancer Potential of COX-2 and 5-LOX Inhibitors: Cytotoxicity, Radiosensitization Potential and Antimigratory Activity against Colorectal and Pancreatic Carcinoma

Pharmaceutics, 2024-06, Vol.16 (6), p.826

2024

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Assessing the potential of solid dispersions to improve dissolution rate and bioavailability of valsartan: In vitro-in silico approach

European journal of pharmaceutical sciences, 2018-11, Vol.124, p.188-198

2018

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Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach

Pharmaceutics, 2021-07, Vol.13 (8), p.1188

2021

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Evaluation of chitosan/xanthan gum polyelectrolyte complexes potential for pH-dependent oral delivery of escin

International journal of biological macromolecules, 2022-11, Vol.221, p.48-60

2022

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Synergism of polysaccharide polymers in antihistamine eye drops: Influence on physicochemical properties and in vivo efficacy

International journal of pharmaceutics, 2024-04, Vol.655, p.124033-124033, Article 124033

2024

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Synthesis, Characterization, and Investigation of Anti-Inflammatory and Cytotoxic Activities of Novel Thiourea Derivatives of Naproxen

Pharmaceutics, 2023-12, Vol.16 (1), p.1

2023

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Nanocrystal dispersion of DK-I-56–1, a poorly soluble pyrazoloquinolinone positive modulator of α6 GABAA receptors: Formulation approach toward improved in vivo performance

European journal of pharmaceutical sciences, 2020-09, Vol.152, p.105432-105432, Article 105432

2020

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Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the γ‑Aminobutyric Acid Type A Receptor (GABAAR) α6 Subtype with Improved Metabolic Stability and Enhanced Bioavailability

Journal of medicinal chemistry, 2018-03, Vol.61 (6), p.2422-2446

2018

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Quantification of oxidative stress markers in the blood sera following subacute administration of different oximes in rats

Chemico-biological interactions, 2024-08, Vol.399, p.111138, Article 111138

2024

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Improvement of conventional anti-cancer drugs as new tools against multidrug resistant tumors

Study of chitosan/xanthan gum polyelectrolyte complexes formation, solid state and influence on ibuprofen release kinetics

Influence of Solid Drug Delivery System Formulation on Poorly Water-Soluble Drug Dissolution and Permeability

Comparison of the Effect of Bioadhesive Polymers on Stability and Drug Release Kinetics of Biocompatible Hydrogels for Topical Application of Ibuprofen

High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances

Prediction of blood–brain barrier permeation of α-adrenergic and imidazoline receptor ligands using PAMPA technique and quantitative-structure permeability relationship analysis

Synthesis, Evaluation of Enzyme Inhibition and Redox Properties of Potential Dual COX-2 and 5-LOX Inhibitors

Synthesis and Investigation of Anti-Inflammatory Activity of New Thiourea Derivatives of Naproxen

Estimation of passive gastrointestinal absorption of new dual DNA gyrase and topoisomerase IV inhibitors using PAMPA and biopartitioning micellar chromatography and quantitative structure-retention relationship analysis

Development of solid lipid microparticles by melt-emulsification/spray-drying processes as carriers for pulmonary drug delivery

Evaluation of critical formulation parameters in design and differentiation of self-microemulsifying drug delivery systems (SMEDDSs) for oral delivery of aciclovir

Selectivity of N(2)-substituted oxotriazinoindole aldose reductase inhibitors is determined by the interaction pattern with Pro301-Arg312 loop of aldehyde reductase

Discovery of Novel Thiophene/Hydrazones: In Vitro and In Silico Studies against Pancreatic Cancer

An electrochemical study of 9-chloroacridine redox behavior and its interaction with double-stranded DNA

Square wave voltammetric study of interaction between 9-acridinyl amino acid derivatives and DNA

Effect of ibuprofen entrapment procedure on physicochemical and controlled drug release performances of chitosan/xanthan gum polyelectrolyte complexes

Unveiling Anticancer Potential of COX-2 and 5-LOX Inhibitors: Cytotoxicity, Radiosensitization Potential and Antimigratory Activity against Colorectal and Pancreatic Carcinoma

Assessing the potential of solid dispersions to improve dissolution rate and bioavailability of valsartan: In vitro-in silico approach

Overcoming the Low Oral Bioavailability of Deuterated Pyrazoloquinolinone Ligand DK-I-60-3 by Nanonization: A Knowledge-Based Approach

Evaluation of chitosan/xanthan gum polyelectrolyte complexes potential for pH-dependent oral delivery of escin

Synergism of polysaccharide polymers in antihistamine eye drops: Influence on physicochemical properties and in vivo efficacy

Synthesis, Characterization, and Investigation of Anti-Inflammatory and Cytotoxic Activities of Novel Thiourea Derivatives of Naproxen

Nanocrystal dispersion of DK-I-56–1, a poorly soluble pyrazoloquinolinone positive modulator of α6 GABAA receptors: Formulation approach toward improved in vivo performance

Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the γ‑Aminobutyric Acid Type A Receptor (GABAAR) α6 Subtype with Improved Metabolic Stability and Enhanced Bioavailability

Quantification of oxidative stress markers in the blood sera following subacute administration of different oximes in rats

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