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Design and Discovery of N‑(2-Methyl-5′-morpholino-6′-((tetrahydro‑2H‑pyran-4-yl)oxy)-[3,3′-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers

Journal of medicinal chemistry, 2017-06, Vol.60 (12), p.4869-4881

2017

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A triazine-based three-directional rigid-rod tecton forms a novel 1D channel structure

Chemical communications (Cambridge, England), 2007-01 (35), p.3637-3639

2007

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Lead Optimization of Spiropyrazolopyridones: A New and Potent Class of Dengue Virus Inhibitors

ACS medicinal chemistry letters, 2015-03, Vol.6 (3), p.344-348

2015

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(+)-Flavipucine, the Missing Member of the Pyridione Epoxide Family of Fungal Antibiotics

European Journal of Organic Chemistry, 2011-09, Vol.2011 (26), p.5156-5162

2011

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Crystallographic characterization and identification of a minor isomer of C84 fullerene

Chemical communications (Cambridge, England), 2008 (43), p.5610

2008

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Preparation, Structural Properties and Thermal Isomerization of Hex-3-ene-1,5-diyne Bridged [2.2]Paracyclophanes

Chemistry : a European journal, 2014-12, Vol.20 (49), p.16360-16376

2014

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MP2 and DFT Calculations on Circulenes and an Attempt to Prepare the Second Lowest Benzolog, [4]Circulene

Chemistry : a European journal, 2008-06, Vol.14 (18), p.5604-5616

2008

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Bulky N-Substituted 1,3-Benzazaphospholes: Access via Pd-Catalyzed C−N and C−P Cross Coupling, Lithiation, and Conversion to Novel PC−PtBu2 Hybrid Ligands

Inorganic chemistry, 2008-08, Vol.47 (15), p.6900-6912

2008

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Cyclophanes. Part LII: Ethynyl[2.2]paracyclophanes - New Building Blocks for Molecular Scaffolding

Synthesis (Stuttgart), 2004-11, Vol.2004 (16), p.2751-2759

2004

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Building complex carbon skeletons with ethynyl[2.2]paracyclophanes

Beilstein journal of organic chemistry, 2014-08, Vol.10 (1), p.2013-2020

2014

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Discovery of Tetrahydropyrazolopyrimidine Carboxamide Derivatives As Potent and Orally Active Antitubercular Agents

ACS medicinal chemistry letters, 2013-05, Vol.4 (5), p.451-455

2013

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The chemical behavior of terminally tert-butylated polyolefins

Beilstein journal of organic chemistry, 2015-07, Vol.11 (1), p.1246-1258

2015

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The preparation of several 1,2,3,4,5-functionalized cyclopentane derivatives

Beilstein journal of organic chemistry, 2013-08, Vol.9 (1), p.1705-1712

2013

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Preparation and NMR spectra of four isomeric diformyl[2.2]paracyclophanes (cyclophanes 66)

Beilstein journal of organic chemistry, 2010-09, Vol.6 (1), p.932-937

2010

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Cycloadditions to Alkenyl[2.2]paracyclophanes

European Journal of Organic Chemistry, 2006-01, Vol.2006 (2), p.335-350

2006

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1,x-Elimination Reactions: Extending the Limits of a Classical Organic Reaction

Chemistry : a European journal, 2007-01, Vol.13 (34), p.9462-9477

2007

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Intramolecular Reactions in Pseudo-Geminally Substituted [2.2]Paracyclophanes

Chemistry : a European journal, 2007-01, Vol.13 (14), p.3950-3963

2007

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4,15-Diamino[2.2]paracyclophane, a Reusable Template for Topochemical Reaction Control in Solution

European journal of organic chemistry, 2002-07, Vol.2002 (14), p.2298-2307

2002

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Design of a Neutral Macrocyclic Ionophore: Synthesis and Binding Properties for Nitrate and Bromide Anions

European journal of organic chemistry, 2002-09, Vol.2002 (17), p.3004-3014

2002

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Use of Intramolecular 1,5-Sulfur–Oxygen and 1,5-Sulfur–Halogen Interactions in the Design of N‑Methyl-5-aryl‑N‑(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine SMN2 Splicing Modulators

Journal of medicinal chemistry, 2021-04, Vol.64 (8), p.4744-4761

2021

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Construction of a 3D-shaped, natural product like fragment library by fragmentation and diversification of natural products

Bioorganic & medicinal chemistry, 2017-02, Vol.25 (3), p.921-925

2017

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General and Efficient [alpha]-Oxygenation of Carbonyl Compounds by TEMPO Induced by Single-Electron-Transfer Oxidation of Their Enolates

European journal of organic chemistry, 2012-08, Vol.2012 (24), p.4461

2012

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Sr5(VIVOF5)3F(H2O)3 refined from a non-merohedrally twinned crystal

Acta crystallographica. Section E, Structure reports online, 2009-06, Vol.65 (Pt 6), p.i46-i47

2009

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Bioinspired co-crystals of Imatinib providing enhanced kinetic solubility

European journal of pharmaceutics and biopharmaceutics, 2018-07, Vol.128, p.290-299

2018

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Discovery of Potent, Highly Selective, and In Vivo Efficacious, Allosteric MALT1 Inhibitors by Iterative Scaffold Morphing

Journal of medicinal chemistry, 2020-12, Vol.63 (23), p.14576-14593

2020

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Design and Discovery of N‑(2-Methyl-5′-morpholino-6′-((tetrahydro‑2H‑pyran-4-yl)oxy)-[3,3′-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers

A triazine-based three-directional rigid-rod tecton forms a novel 1D channel structure

Lead Optimization of Spiropyrazolopyridones: A New and Potent Class of Dengue Virus Inhibitors

(+)-Flavipucine, the Missing Member of the Pyridione Epoxide Family of Fungal Antibiotics

Crystallographic characterization and identification of a minor isomer of C84 fullerene

Preparation, Structural Properties and Thermal Isomerization of Hex-3-ene-1,5-diyne Bridged [2.2]Paracyclophanes

MP2 and DFT Calculations on Circulenes and an Attempt to Prepare the Second Lowest Benzolog, [4]Circulene

Bulky N-Substituted 1,3-Benzazaphospholes: Access via Pd-Catalyzed C−N and C−P Cross Coupling, Lithiation, and Conversion to Novel PC−PtBu2 Hybrid Ligands

Cyclophanes. Part LII: Ethynyl[2.2]paracyclophanes - New Building Blocks for Molecular Scaffolding

Building complex carbon skeletons with ethynyl[2.2]paracyclophanes

Discovery of Tetrahydropyrazolopyrimidine Carboxamide Derivatives As Potent and Orally Active Antitubercular Agents

The chemical behavior of terminally tert-butylated polyolefins

The preparation of several 1,2,3,4,5-functionalized cyclopentane derivatives

Preparation and NMR spectra of four isomeric diformyl[2.2]paracyclophanes (cyclophanes 66)

Cycloadditions to Alkenyl[2.2]paracyclophanes

1,x-Elimination Reactions: Extending the Limits of a Classical Organic Reaction

Intramolecular Reactions in Pseudo-Geminally Substituted [2.2]Paracyclophanes

4,15-Diamino[2.2]paracyclophane, a Reusable Template for Topochemical Reaction Control in Solution

Design of a Neutral Macrocyclic Ionophore: Synthesis and Binding Properties for Nitrate and Bromide Anions

Use of Intramolecular 1,5-Sulfur–Oxygen and 1,5-Sulfur–Halogen Interactions in the Design of N‑Methyl-5-aryl‑N‑(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine SMN2 Splicing Modulators

Construction of a 3D-shaped, natural product like fragment library by fragmentation and diversification of natural products

General and Efficient [alpha]-Oxygenation of Carbonyl Compounds by TEMPO Induced by Single-Electron-Transfer Oxidation of Their Enolates

Sr5(VIVOF5)3F(H2O)3 refined from a non-merohedrally twinned crystal

Bioinspired co-crystals of Imatinib providing enhanced kinetic solubility

Discovery of Potent, Highly Selective, and In Vivo Efficacious, Allosteric MALT1 Inhibitors by Iterative Scaffold Morphing

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