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A targeted knockdown screen of genes coding for phosphoinositide modulators identifies PIP4K2A as required for acute myeloid leukemia cell proliferation and survival

Oncogene, 2015-03, Vol.34 (10), p.1253-1262

2015

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Nuclear Phosphoinositides: Their Regulation and Roles in Nuclear Functions

International journal of molecular sciences, 2019-06, Vol.20 (12), p.2991

2019

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Phospholipid signalling in the nucleus

Biochimica et biophysica acta. Molecular and cell biology of lipids, 1998-12, Vol.1436 (1-2), p.201-232

1998

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74P Characterizing the beta-catenin interactome using inhibitor screens and novel interaction proteomics techniques

Annals of oncology, 2022-10, Vol.33, p.S1406-S1406

2022

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Inositol lipids are regulated during cell cycle progression in the nuclei of murine erythroleukaemia cells

Biochemical journal, 2001-08, Vol.357 (Pt 3), p.905-910

2001

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275 Modulation of PIP2 levels through small molecule inhibition of PIP5K

European journal of cancer (1990), 2014-11, Vol.50, p.91-91

2014

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Inositides and the nucleus and inositides in the nucleus

Cell, 1993-08, Vol.74 (3), p.405-407

1993

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Identification of a new polyphosphoinositide in plants, phosphatidylinositol 5-monophosphate (PtdIns5P), and its accumulation upon osmotic stress

Biochemical journal, 2001-12, Vol.360 (Pt 2), p.491-498

2001

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The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF‐I) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein kinase C to the nucleus

The EMBO journal, 1991-11, Vol.10 (11), p.3207-3214

1991

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Mammalian SIRT1 Represses Forkhead Transcription Factors

Cell, 2004-02, Vol.116 (4), p.551-563

2004

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A novel pathway of cellular phosphatidylinositol(3,4,5)-trisphosphate synthesis is regulated by oxidative stress

Current biology, 2001-03, Vol.11 (6), p.386-395

2001

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The PHD Finger of the Chromatin-Associated Protein ING2 Functions as a Nuclear Phosphoinositide Receptor

Cell, 2003-07, Vol.114 (1), p.99-111

2003

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Phosphoinositide signalling enzymes in rat liver nuclei : phosphoinositidase C isoform β1 is specifically, but not predominantly, located in the nucleus

Biochemical journal, 1993, Vol.289, p.617-620

1993

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Aggregation‐dependent, integrin‐mediated increases in cytoskeletally associated PtdInsP2 (4,5) levels in human platelets are controlled by translocation of PtdIns 4‐P 5‐kinase C to the cytoskeleton

The EMBO journal, 1996-12, Vol.15 (23), p.6516-6524

1996

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Nuclear diacylglycerol is increased during cell proliferation in vivo

Biochemical journal, 1993-03, Vol.290 (3), p.633-636

1993

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The cloning and sequence of the C isoform of PtdIns4P 5-kinase

Biochemical journal, 1995-08, Vol.309 ( Pt 3) (Pt 3), p.715-719

1995

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Nuclear inositides: inconsistent consistencies

Cellular and molecular life sciences : CMLS, 2000-03, Vol.57 (3), p.379-393

2000

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Constitutive active GTPases Rac and Cdc42 are associated with endoreplication in PAE cells

European journal of cancer (1990), 2002-09, Vol.38 (13), p.1775-1782

2002

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Changes in the components of a nuclear inositide cycle during differentiation in murine erythroleukaemia cells

Biochemical journal, 1995-11, Vol.312 ( Pt 1) (1), p.63-67

1995

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Phospholipid signaling

Cell, 1995-01, Vol.80 (2), p.269-278

1995

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Linking lipids to chromatin

Current opinion in genetics & development, 2004-04, Vol.14 (2), p.196-202

2004

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Long-term starvation and ageing induce AGE-1/PI 3-kinase-dependent translocation of DAF-16/FOXO to the cytoplasm

BMC biology, 2006-02, Vol.4 (1), p.1-1, Article 1

2006

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The C-terminal Domain of Rac1 Contains Two Motifs That Control Targeting and Signaling Specificity

The Journal of biological chemistry, 2003-10, Vol.278 (40), p.39166-39175

2003

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Translocation of Diacylglycerol Kinase θ from Cytosol to Plasma Membrane in Response to Activation of G Protein-coupled Receptors and Protein Kinase C

The Journal of biological chemistry, 2005-03, Vol.280 (11), p.9870-9878

2005

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Diacylglycerol kinase counteracts protein kinase C-mediated inactivation of the EGF receptor

The international journal of biochemistry & cell biology, 2012, Vol.44 (11)

2012

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A targeted knockdown screen of genes coding for phosphoinositide modulators identifies PIP4K2A as required for acute myeloid leukemia cell proliferation and survival

Nuclear Phosphoinositides: Their Regulation and Roles in Nuclear Functions

Phospholipid signalling in the nucleus

74P Characterizing the beta-catenin interactome using inhibitor screens and novel interaction proteomics techniques

Inositol lipids are regulated during cell cycle progression in the nuclei of murine erythroleukaemia cells

275 Modulation of PIP2 levels through small molecule inhibition of PIP5K

Inositides and the nucleus and inositides in the nucleus

Identification of a new polyphosphoinositide in plants, phosphatidylinositol 5-monophosphate (PtdIns5P), and its accumulation upon osmotic stress

The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF‐I) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein kinase C to the nucleus

Mammalian SIRT1 Represses Forkhead Transcription Factors

A novel pathway of cellular phosphatidylinositol(3,4,5)-trisphosphate synthesis is regulated by oxidative stress

The PHD Finger of the Chromatin-Associated Protein ING2 Functions as a Nuclear Phosphoinositide Receptor

Phosphoinositide signalling enzymes in rat liver nuclei : phosphoinositidase C isoform β1 is specifically, but not predominantly, located in the nucleus

Aggregation‐dependent, integrin‐mediated increases in cytoskeletally associated PtdInsP2 (4,5) levels in human platelets are controlled by translocation of PtdIns 4‐P 5‐kinase C to the cytoskeleton

Nuclear diacylglycerol is increased during cell proliferation in vivo

The cloning and sequence of the C isoform of PtdIns4P 5-kinase

Nuclear inositides: inconsistent consistencies

Constitutive active GTPases Rac and Cdc42 are associated with endoreplication in PAE cells

Changes in the components of a nuclear inositide cycle during differentiation in murine erythroleukaemia cells

Phospholipid signaling

Linking lipids to chromatin

Long-term starvation and ageing induce AGE-1/PI 3-kinase-dependent translocation of DAF-16/FOXO to the cytoplasm

The C-terminal Domain of Rac1 Contains Two Motifs That Control Targeting and Signaling Specificity

Translocation of Diacylglycerol Kinase θ from Cytosol to Plasma Membrane in Response to Activation of G Protein-coupled Receptors and Protein Kinase C

Diacylglycerol kinase counteracts protein kinase C-mediated inactivation of the EGF receptor

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