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Clinical Pharmacogenetics Implementation Consortium Guideline for Cytochrome P450 (CYP)2D6 Genotype and Atomoxetine Therapy

Clinical pharmacology and therapeutics, 2019-07, Vol.106 (1), p.94-102

2019

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The Respective Roles of CYP3A4 and CYP2D6 in the Metabolism of Pimozide to Established and Novel Metabolites

Drug metabolism and disposition, 2020-11, Vol.48 (11), p.1113-1120

2020

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Cardiac Disease Alters Myocardial Tissue Levels of Epoxyeicosatrienoic Acids and Key Proteins Involved in Their Biosynthesis and Degradation

International journal of molecular sciences, 2022-10, Vol.23 (20), p.12433

2022

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Is this the end for ranitidine? NDMA presence continues to confound

Clinical and translational science, 2021-07, Vol.14 (4), p.1197-1200

2021

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S10.3 - Use of ‘Virtual Children’ to inform exposure-controlled dosing of drugs in children

Drug metabolism and pharmacokinetics, 2020, Vol.35 (1), p.S16-S16

Dinh, Jean C.

2020

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Ten Years' Experience with the CYP2D6 Activity Score: A Perspective on Future Investigations to Improve Clinical Predictions for Precision Therapeutics

Journal of personalized medicine, 2018-04, Vol.8 (2), p.15

2018

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Description of an Innovative Pediatric Individualized Therapeutics Clinic: Working toward Precision Drug Therapy

Children (Basel), 2019-02, Vol.6 (2), p.35

2019

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Ontogeny of Scaling Factors for Pediatric Physiology-Based Pharmacokinetic Modeling and Simulation: Microsomal Protein Per Gram of Liver

Drug metabolism and disposition, 2022-01, Vol.50 (1), p.24-32

2022

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The Impact of the CYP2D6 “Enhancer” Single Nucleotide Polymorphism on CYP2D6 Activity

Clinical pharmacology and therapeutics, 2022-03, Vol.111 (3), p.646-654

2022

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Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children

Drug metabolism and disposition, 2016-07, Vol.44 (7), p.1070-1079

2016

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Pediatric Clinical Endpoint and Pharmacodynamic Biomarkers: Limitations and Opportunities

Paediatric drugs, 2020-02, Vol.22 (1), p.55-71

2020

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Potential contribution of cytochrome P450 2B6 to hepatic 4-hydroxycyclophosphamide formation in vitro and in vivo

Drug metabolism and disposition, 2012-01, Vol.40 (1), p.54-63

2012

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P191 - The CYP2D6 ‘enhancer’ SNP: Long-range linkage analysis and impact on activity in human liver tissue

Drug metabolism and pharmacokinetics, 2020, Vol.35 (1), p.S80-S81

2020

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Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 Genotype and Atomoxetine Therapy

Clinical pharmacology and therapeutics, 2019-04, Vol.106 (1), p.94-102

2019

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In vitro and in vivo studies of methadone metabolism and pharmacokinetics

Dinh, Jean C

2014

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Antibiotic treatment for 6 weeks versus 12 weeks in patients with pyogenic vertebral osteomyelitis: an open-label, non-inferiority, randomised, controlled trial

The Lancet (British edition), 2015-03, Vol.385 (9971), p.875-882

2015

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Hypothermia for Neuroprotection in Convulsive Status Epilepticus

The New England journal of medicine, 2016-12, Vol.375 (25), p.2457-2467

2016

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Successful cardiopulmonary resuscitation after cardiac arrest as a sepsis-like syndrome

Circulation (New York, N.Y.), 2002-07, Vol.106 (5), p.562-568

2002

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Innate immune deficiencies are associated with severity and poor prognosis in patients with COVID-19

Scientific reports, 2022-01, Vol.12 (1), p.638-638, Article 638

2022

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Contradictory hydrological impacts of afforestation in the humid tropics evidenced by long-term field monitoring and simulation modelling

Hydrology and earth system sciences, 2016-07, Vol.20 (7), p.2691-2704

2016

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RIS-enabled smart wireless environments: deployment scenarios, network architecture, bandwidth and area of influence

EURASIP journal on wireless communications and networking, 2023-10, Vol.2023 (1), p.103-38, Article 103

2023

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Combination of non-thermal plasma and Pd/LaMnO3 for dilute trichloroethylene abatement

Chemical engineering journal (Lausanne, Switzerland : 1996), 2016-01, Vol.283, p.668-675

2016

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Branching and nucleokinesis defects in migrating interneurons derived from doublecortin knockout mice

Human molecular genetics, 2006-05, Vol.15 (9), p.1387-1400

2006

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Discovery of 1‑{(3R,4R)‑3-[({5-Chloro-2-[(1-methyl‑1H‑pyrazol-4-yl)amino]‑7H‑pyrrolo[2,3‑d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants

Journal of medicinal chemistry, 2016-03, Vol.59 (5), p.2005-2024

2016

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2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

European heart journal, 2022-10, Vol.43 (38), p.3618-3731

2022

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Clinical Pharmacogenetics Implementation Consortium Guideline for Cytochrome P450 (CYP)2D6 Genotype and Atomoxetine Therapy

The Respective Roles of CYP3A4 and CYP2D6 in the Metabolism of Pimozide to Established and Novel Metabolites

Cardiac Disease Alters Myocardial Tissue Levels of Epoxyeicosatrienoic Acids and Key Proteins Involved in Their Biosynthesis and Degradation

Is this the end for ranitidine? NDMA presence continues to confound

S10.3 - Use of ‘Virtual Children’ to inform exposure-controlled dosing of drugs in children

Ten Years' Experience with the CYP2D6 Activity Score: A Perspective on Future Investigations to Improve Clinical Predictions for Precision Therapeutics

Description of an Innovative Pediatric Individualized Therapeutics Clinic: Working toward Precision Drug Therapy

Ontogeny of Scaling Factors for Pediatric Physiology-Based Pharmacokinetic Modeling and Simulation: Microsomal Protein Per Gram of Liver

The Impact of the CYP2D6 “Enhancer” Single Nucleotide Polymorphism on CYP2D6 Activity

Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children

Pediatric Clinical Endpoint and Pharmacodynamic Biomarkers: Limitations and Opportunities

Potential contribution of cytochrome P450 2B6 to hepatic 4-hydroxycyclophosphamide formation in vitro and in vivo

P191 - The CYP2D6 ‘enhancer’ SNP: Long-range linkage analysis and impact on activity in human liver tissue

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 Genotype and Atomoxetine Therapy

In vitro and in vivo studies of methadone metabolism and pharmacokinetics

Antibiotic treatment for 6 weeks versus 12 weeks in patients with pyogenic vertebral osteomyelitis: an open-label, non-inferiority, randomised, controlled trial

Hypothermia for Neuroprotection in Convulsive Status Epilepticus

Successful cardiopulmonary resuscitation after cardiac arrest as a sepsis-like syndrome

Innate immune deficiencies are associated with severity and poor prognosis in patients with COVID-19

Contradictory hydrological impacts of afforestation in the humid tropics evidenced by long-term field monitoring and simulation modelling

RIS-enabled smart wireless environments: deployment scenarios, network architecture, bandwidth and area of influence

Combination of non-thermal plasma and Pd/LaMnO3 for dilute trichloroethylene abatement

Branching and nucleokinesis defects in migrating interneurons derived from doublecortin knockout mice

Discovery of 1‑{(3R,4R)‑3-[({5-Chloro-2-[(1-methyl‑1H‑pyrazol-4-yl)amino]‑7H‑pyrrolo[2,3‑d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants

2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

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