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Recent Advances in the Synthesis of Sulfides, Sulfoxides and Sulfones via C-S Bond Construction from Non-Halide Substrates

Catalysts, 2020-11, Vol.10 (11), p.1339

2020

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A novel 4-aminoquinazoline derivative, DHW-208, suppresses the growth of human breast cancer cells by targeting the PI3K/AKT/mTOR pathway

Cell death & disease, 2020-06, Vol.11 (6), p.491-491, Article 491

2020

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ZDQ-0620, a Novel Phosphatidylinositol 3-Kinase Inhibitor, Inhibits Colorectal Carcinoma Cell Proliferation and Suppresses Angiogenesis by Attenuating PI3K/AKT/mTOR Pathway

Frontiers in oncology, 2022-03, Vol.12, p.848952-848952

2022

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DHW-221, a Dual PI3K/mTOR Inhibitor, Overcomes Multidrug Resistance by Targeting P-Glycoprotein (P-gp/ABCB1) and Akt-Mediated FOXO3a Nuclear Translocation in Non-small Cell Lung Cancer

Frontiers in oncology, 2022-05, Vol.12, p.873649

2022

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A computer-aided chem-photodynamic drugs self-delivery system for synergistically enhanced cancer therapy

Asian journal of pharmceutical sciences, 2021-03, Vol.16 (2), p.203-212

2021

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Selective VEGFR inhibitors for anticancer therapeutics in clinical use and clinical trials

Current pharmaceutical design, 2012-07, Vol.18 (20), p.2921

2012

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Antitumor Activity of DFX117 by Dual Inhibition of c-Met and PI3Kα in Non-Small Cell Lung Cancer

Cancers, 2019-05, Vol.11 (5), p.627

2019

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Synthesis and Smo Activity of Some Novel Benzamide Derivatives

Molecules (Basel, Switzerland), 2017-12, Vol.23 (1), p.85

2017

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Dual blocking of PI3K and mTOR signaling by DHW‐221, a novel benzimidazole derivative, exerts antitumor activity in human non‐small cell lung cancer

Clinical and translational medicine, 2021-09, Vol.11 (9), p.e514-n/a

2021

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Synthesis and cytotoxic activity of some novel N-pyridinyl-2-(6-phenylimidazo[2,1-b]thiazol-3-yl)acetamide derivatives

Molecules (Basel, Switzerland), 2012-04, Vol.17 (4), p.4703-4716

2012

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Abstract 6550: WD105, a novel decursin derivative, showed greater growth inhibition and androgen receptor suppression in LNCaP human prostate cancer cells

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.6550-6550

2020

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Design, Synthesis and Biological Evaluation of Sulfenimine Cephalosporin Analogues as β-Lactamase Inhibitors

Chemical research in Chinese universities, 2015-06, Vol.31 (3), p.388-393

2015

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Design, synthesis and biological evaluation of harmine derivatives as potent GSK-3β/DYRK1A dual inhibitors for the treatment of Alzheimer's disease

European journal of medicinal chemistry, 2021-10, Vol.222, p.113554, Article 113554

2021

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A comprehensive description of GluN2B-selective N-methyl-D-aspartate (NMDA) receptor antagonists

European journal of medicinal chemistry, 2020-08, Vol.200, p.112447-112447, Article 112447

2020

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DZW-310, a novel phosphoinositide 3-kinase inhibitor, attenuates the angiogenesis and growth of hepatocellular carcinoma cells via PI3K/AKT/mTOR axis

Biochemical pharmacology, 2022-07, Vol.201, p.115093-115093, Article 115093

2022

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Exploration of 4-(1H-indol-3-yl)cyclohex-3-en-1-amine analogues as HDAC inhibitors: Design, synthesis, biological evaluation and modelling studies

Bioorganic & medicinal chemistry letters, 2022-09, Vol.72, p.128846-128846, Article 128846

2022

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Integration of MyD88 inhibitor into mesoporous cerium oxide nanozymes-based targeted delivery platform for enhancing treatment of ulcerative colitis

Journal of controlled release, 2023-09, Vol.361, p.493-509

2023

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Design, synthesis, and biological evaluation of β-carboline 1,3,4-oxadiazole based hybrids as HDAC inhibitors with potential antitumor effects

Bioorganic & medicinal chemistry letters, 2022-05, Vol.64, p.128663-128663, Article 128663

2022

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Design, synthesis and evaluation of carbamate-bridged amino acid prodrugs of cycloicaritin with improved antitumor activity, aqueous solubility and phase II metabolic stability

European journal of medicinal chemistry, 2024-10, Vol.276, p.116646, Article 116646

2024

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Flavonoid-triazolyl hybrids as potential anti-hepatitis C virus agents: Synthesis and biological evaluation

European journal of medicinal chemistry, 2021-06, Vol.218, p.113395-113395, Article 113395

2021

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Facile synthesis of C1-substituted β-carbolines as CDK4 inhibitors for the treatment of cancer

Bioorganic chemistry, 2022-04, Vol.121, p.105659-105659, Article 105659

2022

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Striking a Balance between Carbonate/Carbamate Linkage Bond- and Reduction-Sensitive Disulfide Bond-Bearing Linker for Tailored Controlled Release: In Situ Covalent-Albumin-Binding Gemcitabine Prodrugs Promote Bioavailability and Tumor Accumulation

Journal of medicinal chemistry, 2018-06, Vol.61 (11), p.4904-4917

2018

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Copper(II) Catalyzed C–H Alkoxylation of 2‐Phenyl Pyridines with Aliphatic Diols

European journal of organic chemistry, 2018-07, Vol.2018 (25), p.3306-3311

2018

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Novel glycyrrhetinic acid conjugated pH-sensitive liposomes for the delivery of doxorubicin and its antitumor activities

RSC advances, 2016-01, Vol.6 (22), p.17782-17791

2016

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Zwitterion‐Driven Shape Program of Prodrug Nanoassemblies with High Stability, High Tumor Accumulation, and High Antitumor Activity

Advanced healthcare materials, 2021-12, Vol.10 (23), p.e2101407-n/a

2021

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Recent Advances in the Synthesis of Sulfides, Sulfoxides and Sulfones via C-S Bond Construction from Non-Halide Substrates

A novel 4-aminoquinazoline derivative, DHW-208, suppresses the growth of human breast cancer cells by targeting the PI3K/AKT/mTOR pathway

ZDQ-0620, a Novel Phosphatidylinositol 3-Kinase Inhibitor, Inhibits Colorectal Carcinoma Cell Proliferation and Suppresses Angiogenesis by Attenuating PI3K/AKT/mTOR Pathway

DHW-221, a Dual PI3K/mTOR Inhibitor, Overcomes Multidrug Resistance by Targeting P-Glycoprotein (P-gp/ABCB1) and Akt-Mediated FOXO3a Nuclear Translocation in Non-small Cell Lung Cancer

A computer-aided chem-photodynamic drugs self-delivery system for synergistically enhanced cancer therapy

Selective VEGFR inhibitors for anticancer therapeutics in clinical use and clinical trials

Antitumor Activity of DFX117 by Dual Inhibition of c-Met and PI3Kα in Non-Small Cell Lung Cancer

Synthesis and Smo Activity of Some Novel Benzamide Derivatives

Dual blocking of PI3K and mTOR signaling by DHW‐221, a novel benzimidazole derivative, exerts antitumor activity in human non‐small cell lung cancer

Synthesis and cytotoxic activity of some novel N-pyridinyl-2-(6-phenylimidazo[2,1-b]thiazol-3-yl)acetamide derivatives

Abstract 6550: WD105, a novel decursin derivative, showed greater growth inhibition and androgen receptor suppression in LNCaP human prostate cancer cells

Design, Synthesis and Biological Evaluation of Sulfenimine Cephalosporin Analogues as β-Lactamase Inhibitors

Design, synthesis and biological evaluation of harmine derivatives as potent GSK-3β/DYRK1A dual inhibitors for the treatment of Alzheimer's disease

A comprehensive description of GluN2B-selective N-methyl-D-aspartate (NMDA) receptor antagonists

DZW-310, a novel phosphoinositide 3-kinase inhibitor, attenuates the angiogenesis and growth of hepatocellular carcinoma cells via PI3K/AKT/mTOR axis

Exploration of 4-(1H-indol-3-yl)cyclohex-3-en-1-amine analogues as HDAC inhibitors: Design, synthesis, biological evaluation and modelling studies

Integration of MyD88 inhibitor into mesoporous cerium oxide nanozymes-based targeted delivery platform for enhancing treatment of ulcerative colitis

Design, synthesis, and biological evaluation of β-carboline 1,3,4-oxadiazole based hybrids as HDAC inhibitors with potential antitumor effects

Design, synthesis and evaluation of carbamate-bridged amino acid prodrugs of cycloicaritin with improved antitumor activity, aqueous solubility and phase II metabolic stability

Flavonoid-triazolyl hybrids as potential anti-hepatitis C virus agents: Synthesis and biological evaluation

Facile synthesis of C1-substituted β-carbolines as CDK4 inhibitors for the treatment of cancer

Striking a Balance between Carbonate/Carbamate Linkage Bond- and Reduction-Sensitive Disulfide Bond-Bearing Linker for Tailored Controlled Release: In Situ Covalent-Albumin-Binding Gemcitabine Prodrugs Promote Bioavailability and Tumor Accumulation

Copper(II) Catalyzed C–H Alkoxylation of 2‐Phenyl Pyridines with Aliphatic Diols

Novel glycyrrhetinic acid conjugated pH-sensitive liposomes for the delivery of doxorubicin and its antitumor activities

Zwitterion‐Driven Shape Program of Prodrug Nanoassemblies with High Stability, High Tumor Accumulation, and High Antitumor Activity

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