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Wnts in action: from synapse formation to synaptic maintenance

Frontiers in cellular neuroscience, 2013-11, Vol.7, p.162-162

2013

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The secreted Wnt antagonist Dickkopf-1 is required for amyloid β-mediated synaptic loss

The Journal of neuroscience, 2012-03, Vol.32 (10), p.3492-3498

2012

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Pre-clinical pharmacokinetics of UK-453,061, a novel non-nucleoside reverse transcriptase inhibitor (NNRTI), and use of in silico physiologically based prediction tools to predict the oral pharmacokinetics of UK-453,061 in man

Xenobiotica, 2008-06, Vol.38 (6), p.620-640

2008

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Diversity of Campylobacter isolates from retail poultry carcasses and from humans as demonstrated by pulsed-field gel electrophoresis

Journal of food protection, 2002-06, Vol.65 (6), p.957-962

2002

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An interaction between the cytochrome P450 probe substrates chlorzoxazone (CYP2E1) and midazolam (CYP3A)

British journal of clinical pharmacology, 2001-11, Vol.52 (5), p.555-561

2001

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Induction of cytochromes P450

Current topics in medicinal chemistry, 2004-01, Vol.4 (16), p.1745

Dickins, Maurice

2004

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Problems of a Late Palaeozoic glaciation in Australia and subsequent climate in the Permian

Palaeogeography, palaeoclimatology, palaeoecology, 1996-10, Vol.125 (1), p.185-197

Dickins, J.M.

1996

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Application of a generic fast gradient liquid chromatography tandem mass spectrometry method for the analysis of cytochrome P450 probe substrates

Rapid communications in mass spectrometry, 1998-03, Vol.12 (5), p.217-224

1998

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Structural determinants of cytochrome P450 substrate specificity, binding affinity and catalytic rate

Chemico-biological interactions, 1998-10, Vol.115 (3), p.175-199

1998

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Factors influencing rates and clearance in P450-mediated reactions: QSARs for substrates of the xenobiotic-metabolizing hepatic microsomal P450s

Toxicology (Amsterdam), 2002-01, Vol.170 (1), p.45-53

2002

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Permian-Triassic Evolution of Tethys and Western Circum-Pacific

1, 2000

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Compound lipophilicity for substrate binding to human P450s in drug metabolism

Drug Discovery Today, 2004-06, Vol.9 (12), p.530-537

2004

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Quantitative structure–activity relationships for inducers of cytochromes P450 and nuclear receptor ligands involved in P450 regulation within the CYP1, CYP2, CYP3 and CYP4 families

Toxicology (Amsterdam), 2002-07, Vol.176 (1), p.51-57

2002

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Homology modelling of human CYP1A2 based on the CYP2C5 crystallographic template structure

Xenobiotica, 2003-03, Vol.33 (3), p.239-254

2003

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QUALITY IS PERSONAL: NEGOTIATING CHOICE AND RISK IN COMMUNITY BASED DEMENTIA CARE

Innovation in aging, 2017-07, Vol.1 (suppl_1), p.341-342

2017

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Quantitative structure-activity relationships within a homologous series of 7-alkoxyresorufins exhibiting activity towards CYP1A and CYP2B enzymes: molecular modelling studies on key members of the resorufin series with CYP2C5-derived models of human CYP1A1, CYP1A2, CYP2B6 and CYP3A4

Xenobiotica, 2004-06, Vol.34 (6), p.501-513

2004

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Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the putative active site of the human CYP2E1 isoform

Xenobiotica, 2000, Vol.30 (1), p.1-25

2000

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Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: investigation of enzyme–substrate and enzyme–inhibitor interactions

Toxicology in vitro, 2003-02, Vol.17 (1), p.93-105

2003

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Homology modelling of CYP3A4 from the CYP2C5 crystallographic template: analysis of typical CYP3A4 substrate interactions

Xenobiotica, 2004-06, Vol.34 (6), p.549-569

2004

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A comparison of basal and induced hepatic microsomal cytochrome P450 monooxygenase activities in the cynomolgus monkey (Macaca fascicularis) and man

Xenobiotica, 1999, Vol.29 (5), p.467-482

1999

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The dielectric properties of zirconia

Journal of materials science, 1992-01, Vol.27 (8), p.2267-2271

1992

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Molecular modelling of CYP2B6, the human CYP2B isoform, by homology with the substrate-bound CYP102 crystal structure: evaluation of CYP2B6 substrate characteristics, the cytochrome b5 binding site and comparisons with CYP2B1 and CYP2B4

Xenobiotica, 1999, Vol.29 (4), p.361-393

1999

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Homology modelling of CYP2A6 based on the CYP2C5 crystallographic template: enzyme–substrate interactions and QSARs for binding affinity and inhibition

Toxicology in vitro, 2003-04, Vol.17 (2), p.179-190

2003

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Molecular modelling of the human cytochrome P450 isoform CYP2A6 and investigations of CYP2A substrate selectivity

Toxicology (Amsterdam), 1999-03, Vol.133 (1), p.1-33

1999

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Climate of the Late Devonian to Triassic

Palaeogeography, palaeoclimatology, palaeoecology, 1993, Vol.100 (1), p.89-94

Dickins, J.M.

1993

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Wnts in action: from synapse formation to synaptic maintenance

The secreted Wnt antagonist Dickkopf-1 is required for amyloid β-mediated synaptic loss

Pre-clinical pharmacokinetics of UK-453,061, a novel non-nucleoside reverse transcriptase inhibitor (NNRTI), and use of in silico physiologically based prediction tools to predict the oral pharmacokinetics of UK-453,061 in man

Diversity of Campylobacter isolates from retail poultry carcasses and from humans as demonstrated by pulsed-field gel electrophoresis

An interaction between the cytochrome P450 probe substrates chlorzoxazone (CYP2E1) and midazolam (CYP3A)

Induction of cytochromes P450

Problems of a Late Palaeozoic glaciation in Australia and subsequent climate in the Permian

Application of a generic fast gradient liquid chromatography tandem mass spectrometry method for the analysis of cytochrome P450 probe substrates

Structural determinants of cytochrome P450 substrate specificity, binding affinity and catalytic rate

Factors influencing rates and clearance in P450-mediated reactions: QSARs for substrates of the xenobiotic-metabolizing hepatic microsomal P450s

Permian-Triassic Evolution of Tethys and Western Circum-Pacific

Compound lipophilicity for substrate binding to human P450s in drug metabolism

Quantitative structure–activity relationships for inducers of cytochromes P450 and nuclear receptor ligands involved in P450 regulation within the CYP1, CYP2, CYP3 and CYP4 families

Homology modelling of human CYP1A2 based on the CYP2C5 crystallographic template structure

QUALITY IS PERSONAL: NEGOTIATING CHOICE AND RISK IN COMMUNITY BASED DEMENTIA CARE

Quantitative structure-activity relationships within a homologous series of 7-alkoxyresorufins exhibiting activity towards CYP1A and CYP2B enzymes: molecular modelling studies on key members of the resorufin series with CYP2C5-derived models of human CYP1A1, CYP1A2, CYP2B6 and CYP3A4

Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the putative active site of the human CYP2E1 isoform

Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: investigation of enzyme–substrate and enzyme–inhibitor interactions

Homology modelling of CYP3A4 from the CYP2C5 crystallographic template: analysis of typical CYP3A4 substrate interactions

A comparison of basal and induced hepatic microsomal cytochrome P450 monooxygenase activities in the cynomolgus monkey (Macaca fascicularis) and man

The dielectric properties of zirconia

Molecular modelling of CYP2B6, the human CYP2B isoform, by homology with the substrate-bound CYP102 crystal structure: evaluation of CYP2B6 substrate characteristics, the cytochrome b5 binding site and comparisons with CYP2B1 and CYP2B4

Homology modelling of CYP2A6 based on the CYP2C5 crystallographic template: enzyme–substrate interactions and QSARs for binding affinity and inhibition

Molecular modelling of the human cytochrome P450 isoform CYP2A6 and investigations of CYP2A substrate selectivity

Climate of the Late Devonian to Triassic

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