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Loss of Transforming Growth Factor Beta Signaling in Aortic Smooth Muscle Cells Causes Endothelial Dysfunction and Aortic Hypercontractility

Arteriosclerosis, thrombosis, and vascular biology, 2021-06, Vol.41 (6), p.1956-1971

2021

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Novel expression cassettes for increasing apolipoprotein AI transgene expression in vascular endothelial cells

Scientific reports, 2022-12, Vol.12 (1), p.21079-12, Article 21079

2022

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Aortopathy in a Mouse Model of Marfan Syndrome Is Not Mediated by Altered Transforming Growth Factor β Signaling

Journal of the American Heart Association, 2017-01, Vol.6 (1), p.n/a

2017

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TGF-β1 Limits Plaque Growth, Stabilizes Plaque Structure, and Prevents Aortic Dilation in Apolipoprotein E-Null Mice

Arteriosclerosis, thrombosis, and vascular biology, 2009-09, Vol.29 (9), p.1251-1257

2009

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Targeting and delivery of microRNA-targeting antisense oligonucleotides in cardiovascular diseases

Atherosclerosis, 2023-06, Vol.374, p.44-54

2023

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Response by Dichek to Letter Regarding Article, "Jugular Vein Injection of High-Titer Lentiviral Vectors Does Not Transduce the Aorta"

Arteriosclerosis, thrombosis, and vascular biology, 2021-04, Vol.41 (4), p.e240

Dichek, David A

2021

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Apolipoprotein A-I vascular gene therapy reduces vein-graft atherosclerosis

Molecular therapy. Methods & clinical development, 2023-09, Vol.30, p.558-572

2023

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TGF-β (Transforming Growth Factor-β) Signaling Protects the Thoracic and Abdominal Aorta From Angiotensin II-Induced Pathology by Distinct Mechanisms

Arteriosclerosis, thrombosis, and vascular biology, 2017-11, Vol.37 (11), p.2102-2113

2017

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Macrophage-targeted overexpression of urokinase causes accelerated atherosclerosis, coronary artery occlusions, and premature death

Circulation (New York, N.Y.), 2004-05, Vol.109 (17), p.2129-2135

2004

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Overexpression of Urokinase by Macrophages or Deficiency of Plasminogen Activator Inhibitor Type 1 Causes Cardiac Fibrosis in Mice

Circulation Research, 2004-09, Vol.95 (6), p.637-644

2004

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Exosome-Mediated Transfer of Anti-miR-33a-5p from Transduced Endothelial Cells Enhances Macrophage and Vascular Smooth Muscle Cell Cholesterol Efflux

Human gene therapy, 2020-02, Vol.31 (3-4), p.219-232

2020

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Local Vascular Gene Therapy With Apolipoprotein A-I to Promote Regression of Atherosclerosis

Arteriosclerosis, thrombosis, and vascular biology, 2017-02, Vol.37 (2), p.316-327

2017

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ABCA1 Overexpression in Endothelial Cells In Vitro Enhances ApoAI-Mediated Cholesterol Efflux and Decreases Inflammation

Human gene therapy, 2019-02, Vol.30 (2), p.236-248

2019

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Apo A-I (Apolipoprotein A-I) Vascular Gene Therapy Provides Durable Protection Against Atherosclerosis in Hyperlipidemic Rabbits

Arteriosclerosis, thrombosis, and vascular biology, 2018-01, Vol.38 (1), p.206-217

2018

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Overexpression of Urokinase by Plaque Macrophages Causes Histological Features of Plaque Rupture and Increases Vascular Matrix Metalloproteinase Activity in Aged Apolipoprotein E-Null Mice

Circulation (New York, N.Y.), 2010-04, Vol.121 (14), p.1637-1644

2010

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Jugular Vein Injection of High-Titer Lentiviral Vectors Does Not Transduce the Aorta-Brief Report

Arteriosclerosis, thrombosis, and vascular biology, 2021-03, Vol.41 (3), p.1149-1155

2021

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Transforming growth factor beta 1 induces neointima formation through plasminogen activator inhibitor-1-dependent pathways

Arteriosclerosis, thrombosis, and vascular biology, 2006-04, Vol.26 (4), p.737-743

2006

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Blockade of TGF-β (Transforming Growth Factor Beta) Signaling by Deletion of Tgfbr2 in Smooth Muscle Cells of 11-Month-Old Mice Alters Aortic Structure and Causes Vasomotor Dysfunction-Brief Report

Arteriosclerosis, thrombosis, and vascular biology, 2022-06, Vol.42 (6), p.764-771

2022

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A Rabbit Model for Testing Helper-Dependent Adenovirus-Mediated Gene Therapy for Vein Graft Atherosclerosis

Molecular therapy. Methods & clinical development, 2017-12, Vol.7 (C), p.96-111

2017

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Plasminogen mediates the atherogenic effects of macrophage-expressed urokinase and accelerates atherosclerosis in apoE-knockout mice

Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (44), p.17109-17114

2008

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Postnatal Deletion of the Type II Transforming Growth Factor-β Receptor in Smooth Muscle Cells Causes Severe Aortopathy in Mice

Arteriosclerosis, thrombosis, and vascular biology, 2015-12, Vol.35 (12), p.2647-2656

2015

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N-terminal eGFP-tagging of rabbit apolipoprotein A-I decreases expression and impairs cholesterol-efflux activity

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2023-05, Vol.1868 (5), p.159301-159301, Article 159301

2023

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Stable In Vivo Transgene Expression in Endothelial Cells with Helper-Dependent Adenovirus: Roles of Promoter and Interleukin-10

Human gene therapy, 2017-03, Vol.28 (3), p.255-270

2017

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Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture

Circulation research, 2020-09, Vol.127 (8), p.997-1022

2020

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Mechanisms of Cardiac Fibrosis Induced by Urokinase Plasminogen Activator

The Journal of biological chemistry, 2006-06, Vol.281 (22), p.15345-15351

2006

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Loss of Transforming Growth Factor Beta Signaling in Aortic Smooth Muscle Cells Causes Endothelial Dysfunction and Aortic Hypercontractility

Novel expression cassettes for increasing apolipoprotein AI transgene expression in vascular endothelial cells

Aortopathy in a Mouse Model of Marfan Syndrome Is Not Mediated by Altered Transforming Growth Factor β Signaling

TGF-β1 Limits Plaque Growth, Stabilizes Plaque Structure, and Prevents Aortic Dilation in Apolipoprotein E-Null Mice

Targeting and delivery of microRNA-targeting antisense oligonucleotides in cardiovascular diseases

Response by Dichek to Letter Regarding Article, "Jugular Vein Injection of High-Titer Lentiviral Vectors Does Not Transduce the Aorta"

Apolipoprotein A-I vascular gene therapy reduces vein-graft atherosclerosis

TGF-β (Transforming Growth Factor-β) Signaling Protects the Thoracic and Abdominal Aorta From Angiotensin II-Induced Pathology by Distinct Mechanisms

Macrophage-targeted overexpression of urokinase causes accelerated atherosclerosis, coronary artery occlusions, and premature death

Overexpression of Urokinase by Macrophages or Deficiency of Plasminogen Activator Inhibitor Type 1 Causes Cardiac Fibrosis in Mice

Exosome-Mediated Transfer of Anti-miR-33a-5p from Transduced Endothelial Cells Enhances Macrophage and Vascular Smooth Muscle Cell Cholesterol Efflux

Local Vascular Gene Therapy With Apolipoprotein A-I to Promote Regression of Atherosclerosis

ABCA1 Overexpression in Endothelial Cells In Vitro Enhances ApoAI-Mediated Cholesterol Efflux and Decreases Inflammation

Apo A-I (Apolipoprotein A-I) Vascular Gene Therapy Provides Durable Protection Against Atherosclerosis in Hyperlipidemic Rabbits

Overexpression of Urokinase by Plaque Macrophages Causes Histological Features of Plaque Rupture and Increases Vascular Matrix Metalloproteinase Activity in Aged Apolipoprotein E-Null Mice

Jugular Vein Injection of High-Titer Lentiviral Vectors Does Not Transduce the Aorta-Brief Report

Transforming growth factor beta 1 induces neointima formation through plasminogen activator inhibitor-1-dependent pathways

Blockade of TGF-β (Transforming Growth Factor Beta) Signaling by Deletion of Tgfbr2 in Smooth Muscle Cells of 11-Month-Old Mice Alters Aortic Structure and Causes Vasomotor Dysfunction-Brief Report

A Rabbit Model for Testing Helper-Dependent Adenovirus-Mediated Gene Therapy for Vein Graft Atherosclerosis

Plasminogen mediates the atherogenic effects of macrophage-expressed urokinase and accelerates atherosclerosis in apoE-knockout mice

Postnatal Deletion of the Type II Transforming Growth Factor-β Receptor in Smooth Muscle Cells Causes Severe Aortopathy in Mice

N-terminal eGFP-tagging of rabbit apolipoprotein A-I decreases expression and impairs cholesterol-efflux activity

Stable In Vivo Transgene Expression in Endothelial Cells with Helper-Dependent Adenovirus: Roles of Promoter and Interleukin-10

Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture

Mechanisms of Cardiac Fibrosis Induced by Urokinase Plasminogen Activator

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