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Effects of an Anti-TSLP Antibody on Allergen-Induced Asthmatic Responses

The New England journal of medicine, 2014-05, Vol.370 (22), p.2102-2110

2014

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Effect of ketoconazole and diltiazem on the pharmacokinetics of apixaban, an oral direct factor Xa inhibitor

British journal of clinical pharmacology, 2015-05, Vol.79 (5), p.838-846

2015

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Effects of AMG 145 on Low-Density Lipoprotein Cholesterol Levels: Results From 2 Randomized, Double-Blind, Placebo-Controlled, Ascending-Dose Phase 1 Studies in Healthy Volunteers and Hypercholesterolemic Subjects on Statins

Journal of the American College of Cardiology, 2012-11, Vol.60 (19), p.1888-1898

2012

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Effect of Rifampin on the Pharmacokinetics of Apixaban, an Oral Direct Inhibitor of Factor Xa

American journal of cardiovascular drugs : drugs, devices, and other interventions, 2016-04, Vol.16 (2), p.119-127

2016

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Evaluation of Evolocumab (AMG 145), a Fully Human Anti‐PCSK9 IgG2 Monoclonal Antibody, in Subjects With Hepatic Impairment

Journal of clinical pharmacology, 2017-04, Vol.57 (4), p.513-523

2017

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Effects of AMG 145 on Low-Density Lipoprotein Cholesterol Levels

Journal of the American College of Cardiology, 2012-11, Vol.60 (19), p.1888-1898

2012

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Pharmacokinetics, Safety, and Tolerability of Tezepelumab (AMG 157) in Healthy and Atopic Dermatitis Adult Subjects

Clinical pharmacology and therapeutics, 2019-08, Vol.106 (2), p.441-449

2019

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Tolerability of High-Volume Subcutaneous Injections of a Viscous Placebo Buffer: A Randomized, Crossover Study in Healthy Subjects

AAPS PharmSciTech, 2015-10, Vol.16 (5), p.1101-1107

2015

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Response to ‘Inclusion of Placebos and Blinding for Ascending Dose First‐in‐Human Studies and Other Underpowered Phase 1 studies has not been Justified and on Balance is Not Useful’ by D.A. Parasrampuria and L.Z. Benet

Basic & clinical pharmacology & toxicology, 2015-12, Vol.117 (6), p.365-366

2015

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Effect of Mono‐ and Di‐acylation on the Ocular Disposition of Ganciclovir: Physicochemical Properties, Ocular Bioreversion, and Antiviral Activity of Short Chain Ester Prodrugs

Journal of pharmaceutical sciences, 2002-03, Vol.91 (3), p.660-668

2002

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Pharmacokinetics, Pharmacodynamics, and Safety of Single-Dose Rivaroxaban in Chronic Hemodialysis

American journal of nephrology, 2016-06, Vol.43 (4), p.229-236

2016

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Effects of Evolocumab on Lipoprotein Particles & Subclasses in Hypercholesterolemic & Heterozygous Familial Hypercholesterolemia Subjects on Statin

Journal of clinical lipidology, 2014-05, Vol.8 (3), p.350-351

2014

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Posterior Segment Ocular Pharmacokinetics Using Microdialysis in a Conscious Rabbit Model

Investigative ophthalmology & visual science, 2003-01, Vol.44 (1), p.300-305

2003

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EFFECTS OF EVOLOCUMAB ON LIPOPROTEIN PARTICLES AND SUBCLASSES IN HYPERCHOLESTEROLEMIC AND HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA SUBJECTS ON STATIN THERAPY

Journal of the American College of Cardiology, 2014-04, Vol.63 (12), p.A1378-A1378

2014

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Vitreal Elimination Kinetics of Large Molecular Weight FITC‐Labeled Dextrans in Albino Rabbits Using a Novel Microsampling Technique

Journal of pharmaceutical sciences, 2000-05, Vol.89 (5), p.572-578

2000

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Erratum to: Tolerability of High-Volume Subcutaneous Injections of a Viscous Placebo Buffer: A Randomized, Crossover Study in Healthy Subjects

AAPS PharmSciTech, 2015-12, Vol.16 (6), p.1500-1500

2015

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Rationale for Sponsor-unblinded Phase 1 Trials: Challenging the Double-blind Paradigm

Drug information journal, 2010-01, Vol.44 (1), p.21-27

2010

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Effect of ketoconazole and diltiazem on the pharmacokinetics of apixaban, an oral direct factor X a inhibitor

British journal of clinical pharmacology, 2015-05, Vol.79 (5), p.838-846

2015

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Rivaroxaban in Chronic Hemodialysis Patients: Clarification of an Editorial Error

American journal of nephrology, 2016-09, Vol.44 (2), p.169-169

2016

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A Phase I, Randomized, Double-Blind, Single-Dose, Placebo-Controlled Safety, Tolerability, And Pharmacokinetic/Pharmacodynamic Study Of Evolocumab In Healthy Chinese Subjects

Clinical pharmacology: advances and applications, 2019-10, p.145

2019

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EFFECTS OF EVOLOCUMAB ON LIPOPROTEIN PARTICLES AND SUBCLASSES IN HYPERCHOLESTEROLEMIC AND HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA SUBJECTS ON STATIN THERAPY

Journal of the American College of Cardiology, 2014, Vol.63 (12), p.A1378-A1378

2014

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A Phase 1, Randomized, Double-Blind, Single-Dose, Placebo-Controlled Safety, Tolerability, And Pharmacokinetic/Pharmacodynamic Study Of Evolocumab In Healthy Chinese Subjects

Clinical pharmacology: advances and applications, 2019, Vol.11, p.145-153

2019

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EFFECTS OF AMG 145, A FULLY HUMAN MONOCLONAL ANTIBODY AGAINST PCSK9, ON LOW-DENSITY LIPOPROTEIN CHOLESTEROL IN SUBJECTS TAKING STATINS: A PHASE 1, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, ASCENDING MULTIPLE-DOSE STUDY

Journal of the American College of Cardiology, 2012-03, Vol.59 (13), p.E1379-E1379

2012

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Ocular penetration of acyclovir and its peptide prodrugs valacyclovir and val-valacyclovir following systemic administration in rabbits: An evaluation using ocular microdialysis and LC-MS

Current eye research, 2002-10, Vol.25 (4), p.243-252

2002

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AMG 145, a Fully Human Monoclonal Antibody Against PCSK9, Reduces LDL-C in Healthy Volunteers and Patients on Stable Doses of Statins

Journal of clinical lipidology, 2012-05, Vol.6 (3), p.286-287

2012

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Effects of an Anti-TSLP Antibody on Allergen-Induced Asthmatic Responses

Effect of ketoconazole and diltiazem on the pharmacokinetics of apixaban, an oral direct factor Xa inhibitor

Effects of AMG 145 on Low-Density Lipoprotein Cholesterol Levels: Results From 2 Randomized, Double-Blind, Placebo-Controlled, Ascending-Dose Phase 1 Studies in Healthy Volunteers and Hypercholesterolemic Subjects on Statins

Effect of Rifampin on the Pharmacokinetics of Apixaban, an Oral Direct Inhibitor of Factor Xa

Evaluation of Evolocumab (AMG 145), a Fully Human Anti‐PCSK9 IgG2 Monoclonal Antibody, in Subjects With Hepatic Impairment

Effects of AMG 145 on Low-Density Lipoprotein Cholesterol Levels

Pharmacokinetics, Safety, and Tolerability of Tezepelumab (AMG 157) in Healthy and Atopic Dermatitis Adult Subjects

Tolerability of High-Volume Subcutaneous Injections of a Viscous Placebo Buffer: A Randomized, Crossover Study in Healthy Subjects

Response to ‘Inclusion of Placebos and Blinding for Ascending Dose First‐in‐Human Studies and Other Underpowered Phase 1 studies has not been Justified and on Balance is Not Useful’ by D.A. Parasrampuria and L.Z. Benet

Effect of Mono‐ and Di‐acylation on the Ocular Disposition of Ganciclovir: Physicochemical Properties, Ocular Bioreversion, and Antiviral Activity of Short Chain Ester Prodrugs

Pharmacokinetics, Pharmacodynamics, and Safety of Single-Dose Rivaroxaban in Chronic Hemodialysis

Effects of Evolocumab on Lipoprotein Particles & Subclasses in Hypercholesterolemic & Heterozygous Familial Hypercholesterolemia Subjects on Statin

Posterior Segment Ocular Pharmacokinetics Using Microdialysis in a Conscious Rabbit Model

EFFECTS OF EVOLOCUMAB ON LIPOPROTEIN PARTICLES AND SUBCLASSES IN HYPERCHOLESTEROLEMIC AND HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA SUBJECTS ON STATIN THERAPY

Vitreal Elimination Kinetics of Large Molecular Weight FITC‐Labeled Dextrans in Albino Rabbits Using a Novel Microsampling Technique

Erratum to: Tolerability of High-Volume Subcutaneous Injections of a Viscous Placebo Buffer: A Randomized, Crossover Study in Healthy Subjects

Rationale for Sponsor-unblinded Phase 1 Trials: Challenging the Double-blind Paradigm

Effect of ketoconazole and diltiazem on the pharmacokinetics of apixaban, an oral direct factor X a inhibitor

Rivaroxaban in Chronic Hemodialysis Patients: Clarification of an Editorial Error

A Phase I, Randomized, Double-Blind, Single-Dose, Placebo-Controlled Safety, Tolerability, And Pharmacokinetic/Pharmacodynamic Study Of Evolocumab In Healthy Chinese Subjects

EFFECTS OF EVOLOCUMAB ON LIPOPROTEIN PARTICLES AND SUBCLASSES IN HYPERCHOLESTEROLEMIC AND HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA SUBJECTS ON STATIN THERAPY

A Phase 1, Randomized, Double-Blind, Single-Dose, Placebo-Controlled Safety, Tolerability, And Pharmacokinetic/Pharmacodynamic Study Of Evolocumab In Healthy Chinese Subjects

EFFECTS OF AMG 145, A FULLY HUMAN MONOCLONAL ANTIBODY AGAINST PCSK9, ON LOW-DENSITY LIPOPROTEIN CHOLESTEROL IN SUBJECTS TAKING STATINS: A PHASE 1, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, ASCENDING MULTIPLE-DOSE STUDY

Ocular penetration of acyclovir and its peptide prodrugs valacyclovir and val-valacyclovir following systemic administration in rabbits: An evaluation using ocular microdialysis and LC-MS

AMG 145, a Fully Human Monoclonal Antibody Against PCSK9, Reduces LDL-C in Healthy Volunteers and Patients on Stable Doses of Statins

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