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KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (5), p.1542-1547

2009

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Regulation of T cell alloimmunity by PI3Kγ and PI3Kδ

Nature communications, 2017-10, Vol.8 (1), p.951-11, Article 951

2017

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Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange Factors

Molecular cell, 2007-11, Vol.28 (4), p.569-583

2007

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The Selective Phosphoinoside-3-Kinase p110δ Inhibitor IPI-3063 Potently Suppresses B Cell Survival, Proliferation, and Differentiation

Frontiers in immunology, 2017-06, Vol.8, p.747-747

2017

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Function of activation loop tyrosine phosphorylation in the mechanism of c-Kit auto-activation and its implication in sunitinib resistance

Journal of biochemistry (Tokyo), 2010-04, Vol.147 (4), p.601-609

2010

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Structural determinants of phosphoinositide selectivity in splice variants of Grp1 family PH domains

The EMBO journal, 2004-09, Vol.23 (19), p.3711-3720

2004

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Continuous fluorescence-based method for assessing Dicer cleavage efficiency reveals 3′ overhang nucleotide preference

BioTechniques, 2010-04, Vol.48 (4), p.303-311

2010

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Membrane and juxtamembrane targeting by PH and PTB domains

Biochimica et biophysica acta, 2006-08, Vol.1761 (8), p.850-867

2006

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Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)‑γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate

ACS medicinal chemistry letters, 2016-09, Vol.7 (9), p.862-867

2016

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Molecular mechanisms of drug resistance in tyrosine kinases cAbl and cKit

Critical reviews in biochemistry and molecular biology, 2011-08, Vol.46 (4), p.295-309

2011

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Specificity and Membrane Partitioning of Grsp1 Signaling Complexes with Grp1 Family Arf Exchange Factors

Biochemistry (Easton), 2010-07, Vol.49 (29), p.6083-6092

2010

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Mutual induced fit binding of Xenopus ribosomal protein L5 to 5S rRNA

Journal of molecular biology, 2003-07, Vol.330 (5), p.979-992

2003

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Membrane recognition and targeting by lipid-binding domains

Science's signal transduction knowledge environment (STKE), 2003-12, Vol.2003 (213), p.re16

2003

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Design, Synthesis and Potential Utility of Fluorescence Probes that Target DFG-out Conformation of p38α for High Throughput Screening Binding Assay

Chemical biology & drug design, 2009-12, Vol.74 (6), p.547-559

2009

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A Role for Aromatic Amino Acids in the Binding of Xenopus Ribosomal Protein L5 to 5S rRNA

Biochemistry (Easton), 2001-10, Vol.40 (42), p.12645-12653

2001

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Mutual Induced Fit Binding of Xenopus Ribosomal Protein L5 to 5 S rRNA

Journal of molecular biology, 2003-07, Vol.330 (5), p.979-992

2003

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The design, synthesis and potential utility of fluorescence probes that target DFG-out conformation of p38alpha for high throughput screening binding assay

Chemical biology & drug design, 2009-12, Vol.74 (6), p.547-559

2009

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Modeling readability to improve unit tests

Proceedings of the 2015 10th Joint Meeting on Foundations of Software Engineering, 2015, p.107-118

2015

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Efficient dependency detection for safe Java test acceleration

Proceedings of the 2015 10th Joint Meeting on Foundations of Software Engineering, 2015, p.770-781

2015

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KIT kinase mutants show unique mechanisms of drug resistance to imatinib and sunitinib in gastrointestinal stromal tumor patients

Regulation of T cell alloimmunity by PI3Kγ and PI3Kδ

Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange Factors

The Selective Phosphoinoside-3-Kinase p110δ Inhibitor IPI-3063 Potently Suppresses B Cell Survival, Proliferation, and Differentiation

Function of activation loop tyrosine phosphorylation in the mechanism of c-Kit auto-activation and its implication in sunitinib resistance

Structural determinants of phosphoinositide selectivity in splice variants of Grp1 family PH domains

Continuous fluorescence-based method for assessing Dicer cleavage efficiency reveals 3′ overhang nucleotide preference

Membrane and juxtamembrane targeting by PH and PTB domains

Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)‑γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate

PI3K-δ and PI3K-γ Inhibition by IPI-145 Abrogates Immune Responses and Suppresses Activity in Autoimmune and Inflammatory Disease Models

Molecular mechanisms of drug resistance in tyrosine kinases cAbl and cKit

Specificity and Membrane Partitioning of Grsp1 Signaling Complexes with Grp1 Family Arf Exchange Factors

Mutual induced fit binding of Xenopus ribosomal protein L5 to 5S rRNA

Membrane recognition and targeting by lipid-binding domains

Design, Synthesis and Potential Utility of Fluorescence Probes that Target DFG-out Conformation of p38α for High Throughput Screening Binding Assay

A Role for Aromatic Amino Acids in the Binding of Xenopus Ribosomal Protein L5 to 5S rRNA

Mutual Induced Fit Binding of Xenopus Ribosomal Protein L5 to 5 S rRNA

The design, synthesis and potential utility of fluorescence probes that target DFG-out conformation of p38alpha for high throughput screening binding assay

Modeling readability to improve unit tests

Efficient dependency detection for safe Java test acceleration

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