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Therapeutic potential of CD22-specific antibody-targeted chemotherapy using inotuzumab ozogamicin (CMC-544) for the treatment of acute lymphoblastic leukemia

Leukemia, 2007-11, Vol.21 (11), p.2240-2245

2007

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The oncofetal protein, 5T4, is a suitable target for antibody-guided anti-cancer chemotherapy with calicheamicin

International journal of oncology, 2008, Vol.32 (1), p.221-234

2008

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Synthesis and SAR of bicyclic heteroaryl hydroxamic acid MMP and TACE inhibitors

Bioorganic & medicinal chemistry letters, 2003-04, Vol.13 (8), p.1487-1490

2003

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Antibody-targeted chemotherapy of B-cell lymphoma using calicheamicin conjugated to murine or humanized antibody against CD22

Cancer Immunology, Immunotherapy, 2005-01, Vol.54 (1), p.11-24

2005

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The discovery of anthranilic acid-based mmp inhibitors. Part 3: incorporation of basic amines

Bioorganic & medicinal chemistry letters, 2001-11, Vol.11 (22), p.2975-2978

2001

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The discovery of anthranilic acid-based MMP inhibitors. Part 2: SAR of the 5-position and P1(1) groups

Bioorganic & medicinal chemistry letters, 2001-08, Vol.11 (16), p.2189-2192

2001

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The effect of rapamycin on kidney function in the Sprague-Dawley rat

Transplantation, 1992-03, Vol.53 (3), p.507-512

1992

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The synthesis and biological activity of a novel series of diazepine MMP inhibitors

Bioorganic & medicinal chemistry letters, 1998-10, Vol.8 (19), p.2657-2662

1998

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Therapeutic blood levels of sirolimus (rapamycin) in the allografted rat

Transplantation, 1996-10, Vol.62 (8), p.1109

1996

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CD20-specific antibody-targeted chemotherapy of non-Hodgkin's B-cell lymphoma using calicheamicin-conjugated rituximab

Cancer Immunology, Immunotherapy, 2007-07, Vol.56 (7), p.1107-1117

2007

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The discovery of anthranilic acid-based MMP inhibitors. Part 1: SAR of the 3-position

Bioorganic & medicinal chemistry letters, 2001-01, Vol.11 (2), p.235-238

2001

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Antibody-targeted chemotherapy with CMC-544: a CD22-targeted immunoconjugate of calicheamicin for the treatment of B-lymphoid malignancies

Blood, 2004-03, Vol.103 (5), p.1807-1814

2004

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Antitumor Efficacy of a Combination of CMC-544 (Inotuzumab Ozogamicin), a CD22-Targeted Cytotoxic Immunoconjugate of Calicheamicin, and Rituximab against Non-Hodgkin's B-Cell Lymphoma

Clinical cancer research, 2006-01, Vol.12 (1), p.242-249

2006

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Malonyl α-mercaptoketones and α-mercaptoalcohols, a new class of matrix metalloproteinase inhibitors

Bioorganic & medicinal chemistry letters, 1998-05, Vol.8 (10), p.1157-1162

1998

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The asymmetric synthesis and in vitro characterization of succinyl mercaptoalcohol and mercaptoketone inhibitors of matrix metalloproteinases

Bioorganic & medicinal chemistry letters, 1998-05, Vol.8 (10), p.1163-1168

1998

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Heteroaryl and cycloalkyl sulfonamide hydroxamic acid inhibitors of matrix metalloproteinases

Bioorganic & medicinal chemistry letters, 2001-01, Vol.11 (2), p.239-242

2001

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The discovery of anthranilic acid-based MMP inhibitors. Part 2 : SAR of the 5-position and P11 groups

Bioorganic & medicinal chemistry letters, 2001-08, Vol.11 (16), p.2189-2192

2001

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Renal effects of rapamycin in the spontaneously hypertensive rat

Transplant international, 1994-03, Vol.7 (2), p.83-88

1994

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Potent and Specific Antitumor Efficacy of CMC-544, a CD22-Targeted Immunoconjugate of Calicheamicin, against Systemically Disseminated B-Cell Lymphoma

Clinical cancer research, 2004-12, Vol.10 (24), p.8620-8629

2004

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Influence of rat strain on rapamycin's kidney effects

Transplantation proceedings, 1993-02, Vol.25 (1), p.714-715

1993

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Gastric antisecretory and antiulcer effects of WHR1582A, a compound exerting alpha-2 adrenoceptor agonist activity

The Journal of pharmacology and experimental therapeutics, 1987-04, Vol.241 (1), p.97

1987

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Activated aluminum complex derived from solubilized antacids exhibits enhanced cytoprotective activity in the rat

Gastroenterology (New York, N.Y. 1943), 1989-03, Vol.96 (3), p.730-735

1989

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Dialysis tubing implant assay in the rat: A novel in vivo method for identifying inhibitors of matrix metalloproteinases

Drug development research, 1998-04, Vol.43 (4), p.200-205

1998

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Tumoricidal effect of calicheamicin immuno-conjugates using a passive targeting strategy

International journal of oncology, 2006-03, Vol.28 (3), p.675-684

2006

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Synthesis and Structure−Activity Relationship of N-Substituted 4-Arylsulfonylpiperidine-4-hydroxamic Acids as Novel, Orally Active Matrix Metalloproteinase Inhibitors for the Treatment of Osteoarthritis

Journal of medicinal chemistry, 2003-06, Vol.46 (12), p.2376-2396

2003

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Therapeutic potential of CD22-specific antibody-targeted chemotherapy using inotuzumab ozogamicin (CMC-544) for the treatment of acute lymphoblastic leukemia

The oncofetal protein, 5T4, is a suitable target for antibody-guided anti-cancer chemotherapy with calicheamicin

Synthesis and SAR of bicyclic heteroaryl hydroxamic acid MMP and TACE inhibitors

Antibody-targeted chemotherapy of B-cell lymphoma using calicheamicin conjugated to murine or humanized antibody against CD22

The discovery of anthranilic acid-based mmp inhibitors. Part 3: incorporation of basic amines

The discovery of anthranilic acid-based MMP inhibitors. Part 2: SAR of the 5-position and P1(1) groups

The effect of rapamycin on kidney function in the Sprague-Dawley rat

The synthesis and biological activity of a novel series of diazepine MMP inhibitors

Therapeutic blood levels of sirolimus (rapamycin) in the allografted rat

CD20-specific antibody-targeted chemotherapy of non-Hodgkin's B-cell lymphoma using calicheamicin-conjugated rituximab

The discovery of anthranilic acid-based MMP inhibitors. Part 1: SAR of the 3-position

Antibody-targeted chemotherapy with CMC-544: a CD22-targeted immunoconjugate of calicheamicin for the treatment of B-lymphoid malignancies

Antitumor Efficacy of a Combination of CMC-544 (Inotuzumab Ozogamicin), a CD22-Targeted Cytotoxic Immunoconjugate of Calicheamicin, and Rituximab against Non-Hodgkin's B-Cell Lymphoma

Malonyl α-mercaptoketones and α-mercaptoalcohols, a new class of matrix metalloproteinase inhibitors

The asymmetric synthesis and in vitro characterization of succinyl mercaptoalcohol and mercaptoketone inhibitors of matrix metalloproteinases

Heteroaryl and cycloalkyl sulfonamide hydroxamic acid inhibitors of matrix metalloproteinases

The discovery of anthranilic acid-based MMP inhibitors. Part 2 : SAR of the 5-position and P11 groups

Renal effects of rapamycin in the spontaneously hypertensive rat

Potent and Specific Antitumor Efficacy of CMC-544, a CD22-Targeted Immunoconjugate of Calicheamicin, against Systemically Disseminated B-Cell Lymphoma

Influence of rat strain on rapamycin's kidney effects

Gastric antisecretory and antiulcer effects of WHR1582A, a compound exerting alpha-2 adrenoceptor agonist activity

Activated aluminum complex derived from solubilized antacids exhibits enhanced cytoprotective activity in the rat

Dialysis tubing implant assay in the rat: A novel in vivo method for identifying inhibitors of matrix metalloproteinases

Tumoricidal effect of calicheamicin immuno-conjugates using a passive targeting strategy

Synthesis and Structure−Activity Relationship of N-Substituted 4-Arylsulfonylpiperidine-4-hydroxamic Acids as Novel, Orally Active Matrix Metalloproteinase Inhibitors for the Treatment of Osteoarthritis

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