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Thyroid Development and Its Disorders: Genetics and Molecular Mechanisms

Endocrine reviews, 2004-10, Vol.25 (5), p.722-746

2004

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Minireview: Intrinsic and Extrinsic Factors in Thyroid Gland Development: An Update

Endocrinology (Philadelphia), 2011-08, Vol.152 (8), p.2948-2956

2011

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The microRNA-processing enzyme Dicer is essential for thyroid function

PloS one, 2011-11, Vol.6 (11), p.e27648-e27648

2011

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Pax8 Has a Key Role in Thyroid Cell Differentiation

Proceedings of the National Academy of Sciences - PNAS, 2000-11, Vol.97 (24), p.13144-13149

2000

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Gene expression profiling at early organogenesis reveals both common and diverse mechanisms in foregut patterning

Developmental biology, 2011-11, Vol.359 (2), p.163-175

2011

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An integrated regulatory network controlling survival and migration in thyroid organogenesis

Developmental biology, 2004-12, Vol.276 (2), p.464-475

2004

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Missense Mutation in the Transcription Factor NKX2–5: A Novel Molecular Event in the Pathogenesis of Thyroid Dysgenesis

The journal of clinical endocrinology and metabolism, 2006-04, Vol.91 (4), p.1428-1433

2006

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The Paired Domain-containing Factor Pax8 and the Homeodomain-containing Factor TTF-1 Directly Interact and Synergistically Activate Transcription

The Journal of biological chemistry, 2003-01, Vol.278 (5), p.3395-3402

2003

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Transcriptional Control of the Forkhead Thyroid Transcription Factor TTF-2 by Thyrotropin, Insulin, and Insulin-like Growth Factor I

The Journal of biological chemistry, 1997-09, Vol.272 (37), p.23334-23339

1997

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Replacement of K-Ras with H-Ras supports normal embryonic development despite inducing cardiovascular pathology in adult mice

EMBO reports, 2005-05, Vol.6 (5), p.432-437

2005

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A Mouse Model Demonstrates a Multigenic Origin of Congenital Hypothyroidism

Endocrinology (Philadelphia), 2005-12, Vol.146 (12), p.5038-5047

2005

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The Paired-Domain Transcription Factor Pax8 Binds to the Upstream Enhancer of the Rat Sodium/Iodide Symporter Gene and Participates in Both Thyroid-Specific and Cyclic-AMP-Dependent Transcription

Molecular and Cellular Biology, 1999-03, Vol.19 (3), p.2051-2060

1999

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Erratum to: In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1

BMC developmental biology, 2016-08, Vol.16 (1), p.29-29, Article 29

2016

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Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult

Journal of endocrinology, 2007-03, Vol.192 (3), p.615-626

2007

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In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1

BMC developmental biology, 2011-02, Vol.11 (1), p.9-9, Article 9

2011

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PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis

Nature genetics, 1998-05, Vol.19 (1), p.83-86

1998

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A physiological mechanism to regulate d-aspartic acid and NMDA levels in mammals revealed by d-aspartate oxidase deficient mice

Gene, 2006-06, Vol.374, p.50-57

2006

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Concomitant activation of MEK-1 and Rac-1 increases the proliferative potential of thyroid epithelial cells, without affecting their differentiation

Oncogene, 1998-10, Vol.17 (16), p.2047-2057

1998

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Minireview: Thyrotropin Receptor Signaling in Development and Differentiation of the Thyroid Gland: Insights from Mouse Models and Human Diseases

Endocrinology (Philadelphia), 2004-09, Vol.145 (9), p.4062-4067

2004

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Essential Roles for Fe65, Alzheimer Amyloid Precursor-binding Protein, in the Cellular Response to DNA Damage

The Journal of biological chemistry, 2007-01, Vol.282 (2), p.831-835

2007

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Comparative genomics reveals a functional thyroid-specific element in the far upstream region of the PAX8 gene

BMC genomics, 2010-05, Vol.11 (1), p.306-306, Article 306

2010

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Mapping and Functional Role of Phosphorylation Sites in the Thyroid Transcription Factor-1 (TTF-1)

The Journal of biological chemistry, 1996-01, Vol.271 (4), p.2249-2254

1996

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A Locus on Mouse Chromosome 2 Is Involved in Susceptibility to Congenital Hypothyroidism and Contains an Essential Gene Expressed in Thyroid

Endocrinology (Philadelphia), 2010-04, Vol.151 (4), p.1948-1958

2010

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The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain

Development (Cambridge), 1991-12, Vol.113 (4), p.1093-1104

1991

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A mouse model for hereditary thyroid dysgenesis and cleft palate

Nature genetics, 1998-08, Vol.19 (4), p.395-398

1998

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Thyroid Development and Its Disorders: Genetics and Molecular Mechanisms

Minireview: Intrinsic and Extrinsic Factors in Thyroid Gland Development: An Update

The microRNA-processing enzyme Dicer is essential for thyroid function

Pax8 Has a Key Role in Thyroid Cell Differentiation

Gene expression profiling at early organogenesis reveals both common and diverse mechanisms in foregut patterning

An integrated regulatory network controlling survival and migration in thyroid organogenesis

Missense Mutation in the Transcription Factor NKX2–5: A Novel Molecular Event in the Pathogenesis of Thyroid Dysgenesis

The Paired Domain-containing Factor Pax8 and the Homeodomain-containing Factor TTF-1 Directly Interact and Synergistically Activate Transcription

Transcriptional Control of the Forkhead Thyroid Transcription Factor TTF-2 by Thyrotropin, Insulin, and Insulin-like Growth Factor I

Replacement of K-Ras with H-Ras supports normal embryonic development despite inducing cardiovascular pathology in adult mice

A Mouse Model Demonstrates a Multigenic Origin of Congenital Hypothyroidism

The Paired-Domain Transcription Factor Pax8 Binds to the Upstream Enhancer of the Rat Sodium/Iodide Symporter Gene and Participates in Both Thyroid-Specific and Cyclic-AMP-Dependent Transcription

Erratum to: In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1

Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult

In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1

PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis

A physiological mechanism to regulate d-aspartic acid and NMDA levels in mammals revealed by d-aspartate oxidase deficient mice

Concomitant activation of MEK-1 and Rac-1 increases the proliferative potential of thyroid epithelial cells, without affecting their differentiation

Minireview: Thyrotropin Receptor Signaling in Development and Differentiation of the Thyroid Gland: Insights from Mouse Models and Human Diseases

Essential Roles for Fe65, Alzheimer Amyloid Precursor-binding Protein, in the Cellular Response to DNA Damage

Comparative genomics reveals a functional thyroid-specific element in the far upstream region of the PAX8 gene

Mapping and Functional Role of Phosphorylation Sites in the Thyroid Transcription Factor-1 (TTF-1)

A Locus on Mouse Chromosome 2 Is Involved in Susceptibility to Congenital Hypothyroidism and Contains an Essential Gene Expressed in Thyroid

The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain

A mouse model for hereditary thyroid dysgenesis and cleft palate

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