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Unfolding New Roles for Guanine-Based Purines and Their Metabolizing Enzymes in Cancer and Aging Disorders

Frontiers in pharmacology, 2021-04, Vol.12, p.653549-653549

2021

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Metabotropic Glutamate Receptor Subtypes as Targets for Neuroprotective Drugs

Journal of Cerebral Blood Flow & Metabolism, 2001-09, Vol.21 (9), p.1013-1033

2001

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Synergic development of pharmacokinetics and bioanalytical methods as support of pharmaceutical research

International journal of immunopathology and pharmacology, 2016-06, Vol.29 (2), p.168-179

2016

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Involvement of astrocytes in purine‐mediated reparative processes in the brain

International journal of developmental neuroscience, 2001-07, Vol.19 (4), p.395-414

2001

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Does the purinergic system affect extracellular matrix functions in the central nervous system?

Journal of biological regulators and homeostatic agents, 2018-11, Vol.32 (6), p.1349-1353

2018

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Guanosine protects human neuroblastoma cells from oxidative stress and toxicity induced by Amyloid-beta peptide oligomers

Journal of biological regulators and homeostatic agents, 2010-07, Vol.24 (3), p.297-306

2010

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Tissue distribution and metabolism of guanosine in rats following intraperitoneal injection

Journal of biological regulators and homeostatic agents, 2012-01, Vol.26 (1), p.51-65

2012

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Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways

Journal of neurochemistry, 2001-08, Vol.78 (3), p.435-445

2001

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Regional changes in the metabolite profile after long-term hypoxia-ischemia in brains of young and aged rats: A quantitative proton MRS study

Neurobiology of aging, 2006, Vol.27 (1), p.98-104

2006

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AIT-082 as a potential neuroprotective and regenerative agent in stroke and central nervous system injury

Expert opinion on investigational drugs, 1999-08, Vol.8 (8), p.1255-1262

1999

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Interaction Between A1 Adenosine and Class II Metabotropic Glutamate Receptors in the Regulation of Purine and Glutamate Release from Rat Hippocampal Slices

Journal of neurochemistry, 1996-07, Vol.67 (1), p.302-309

1996

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Activation of P2X(7) receptors stimulates the expression of P2Y(2) receptor mRNA in astrocytes cultured from rat brain

International journal of immunopathology and pharmacology, 2007-04, Vol.20 (2), p.301-316

2007

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Activation of A1 adenosine or mGlu3 metabotropic glutamate receptors enhances the release of nerve growth factor and S-100β protein from cultured astrocytes

Glia, 1999-09, Vol.27 (3), p.275-281

1999

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P2Y2 Receptor Up-Regulation Induced by Guanosine or UTP in Rat Brain Cultured Astrocytes

International journal of immunopathology and pharmacology, 2006-04, Vol.19 (2), p.293-308

2006

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P2Y1 and Cysteinyl Leukotriene Receptors Mediate Purine and Cysteinyl Leukotriene Co-Release in Primary Cultures of Rat Microglia

International journal of immunopathology and pharmacology, 2005-04, Vol.18 (2), p.255-268

2005

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P2X7 Receptor Activation in Rat Brain Cultured Astrocytes Increases the Biosynthetic Release of Cysteinyl Leukotrienes

International journal of immunopathology and pharmacology, 2005-07, Vol.18 (3), p.417-430

2005

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Adenosine and Kynurenic Acid Interactions: Possible Relevance for Schizophrenia Treatment?

Frontiers in pharmacology, 2021-04, Vol.12, p.654426-654426

2021

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AIT-082 Is Neuroprotective against Kainate-Induced Neuronal Injury in Rats

Experimental neurology, 2001-06, Vol.169 (2), p.392-399

2001

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Trophic effects of purines in neurons and glial cells

Progress in neurobiology, 1999-12, Vol.59 (6), p.663-690

1999

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Effects of exogenous ATP and related analogues on the proliferation rate of dissociated primary cultures of rat astrocytes

Journal of neuroscience research, 1994-12, Vol.39 (5), p.556-566

1994

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Inflammation, oxidative stress and platelet activation in aspirin-treated critical limb ischaemia: beneficial effects of iloprost

Thrombosis and haemostasis, 2011-02, Vol.105 (2), p.321-328

2011

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Specific [3H]‐guanosine binding sites in rat brain membranes

British journal of pharmacology, 2002-02, Vol.135 (4), p.969-976

2002

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The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes

Glia, 2004-06, Vol.46 (4), p.356-368

2004

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Glial cells express multiple ATP binding cassette proteins which are involved in ATP release

Neuroreport, 2002-10, Vol.13 (14), p.1789-1792

2002

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Cysteinyl-leukotrienes are released from astrocytes and increase astrocyte proliferation and glial fibrillary acidic protein via cys-LT1 receptors and mitogen-activated protein kinase pathway

The European journal of neuroscience, 2004-09, Vol.20 (6), p.1514-1524

2004

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Unfolding New Roles for Guanine-Based Purines and Their Metabolizing Enzymes in Cancer and Aging Disorders

Metabotropic Glutamate Receptor Subtypes as Targets for Neuroprotective Drugs

Synergic development of pharmacokinetics and bioanalytical methods as support of pharmaceutical research

Involvement of astrocytes in purine‐mediated reparative processes in the brain

Does the purinergic system affect extracellular matrix functions in the central nervous system?

Guanosine protects human neuroblastoma cells from oxidative stress and toxicity induced by Amyloid-beta peptide oligomers

Tissue distribution and metabolism of guanosine in rats following intraperitoneal injection

Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways

Regional changes in the metabolite profile after long-term hypoxia-ischemia in brains of young and aged rats: A quantitative proton MRS study

AIT-082 as a potential neuroprotective and regenerative agent in stroke and central nervous system injury

Interaction Between A1 Adenosine and Class II Metabotropic Glutamate Receptors in the Regulation of Purine and Glutamate Release from Rat Hippocampal Slices

Activation of P2X(7) receptors stimulates the expression of P2Y(2) receptor mRNA in astrocytes cultured from rat brain

Activation of A1 adenosine or mGlu3 metabotropic glutamate receptors enhances the release of nerve growth factor and S-100β protein from cultured astrocytes

P2Y2 Receptor Up-Regulation Induced by Guanosine or UTP in Rat Brain Cultured Astrocytes

P2Y1 and Cysteinyl Leukotriene Receptors Mediate Purine and Cysteinyl Leukotriene Co-Release in Primary Cultures of Rat Microglia

P2X7 Receptor Activation in Rat Brain Cultured Astrocytes Increases the Biosynthetic Release of Cysteinyl Leukotrienes

Adenosine and Kynurenic Acid Interactions: Possible Relevance for Schizophrenia Treatment?

AIT-082 Is Neuroprotective against Kainate-Induced Neuronal Injury in Rats

Trophic effects of purines in neurons and glial cells

Effects of exogenous ATP and related analogues on the proliferation rate of dissociated primary cultures of rat astrocytes

Inflammation, oxidative stress and platelet activation in aspirin-treated critical limb ischaemia: beneficial effects of iloprost

Specific [3H]‐guanosine binding sites in rat brain membranes

The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes

Glial cells express multiple ATP binding cassette proteins which are involved in ATP release

Cysteinyl-leukotrienes are released from astrocytes and increase astrocyte proliferation and glial fibrillary acidic protein via cys-LT1 receptors and mitogen-activated protein kinase pathway

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