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Redox proteomics analysis of HNE-modified proteins in Down syndrome brain: clues for understanding the development of Alzheimer disease

Free radical biology & medicine, 2014-06, Vol.71, p.270-280

2014

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High-Fat Diet Leads to Reduced Protein O-GlcNAcylation and Mitochondrial Defects Promoting the Development of Alzheimer's Disease Signatures

International journal of molecular sciences, 2021-04, Vol.22 (7), p.3746

2021

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BVR-A Deficiency Leads to Autophagy Impairment through the Dysregulation of AMPK/mTOR Axis in the Brain—Implications for Neurodegeneration

Antioxidants, 2020-08, Vol.9 (8), p.671

2020

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Role of 4-hydroxy-2-nonenal (HNE) in the pathogenesis of alzheimer disease and other selected age-related neurodegenerative disorders

Free radical biology & medicine, 2017-10, Vol.111, p.253-261

2017

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mTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy

Neurobiology of disease, 2015-12, Vol.84, p.39-49

2015

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Glutathionylation of the Pro-apoptotic Protein p53 in Alzheimer’s Disease Brain: Implications for AD Pathogenesis

Neurochemical research, 2009-04, Vol.34 (4), p.727-733

2009

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The Triangle of Death in Alzheimer's Disease Brain: The Aberrant Cross-Talk Among Energy Metabolism, Mammalian Target of Rapamycin Signaling, and Protein Homeostasis Revealed by Redox Proteomics

Antioxidants & redox signaling, 2017-03, Vol.26 (8), p.364-387

2017

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Statins more than cholesterol lowering agents in Alzheimer disease: Their pleiotropic functions as potential therapeutic targets

Biochemical pharmacology, 2014-04, Vol.88 (4), p.605-616

2014

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The Janus face of the heme oxygenase/biliverdin reductase system in Alzheimer disease: It's time for reconciliation

Neurobiology of disease, 2014-02, Vol.62, p.144-159

2014

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DECIPHERING THE NOXIOUS INTERPLAY BETWEEN THE UNFOLDED PROTEIN RESPONSE AND ANTIOXIDANT RESPONSES UNDER ABERRANT METABOLIC STIMULI ASSOCIATED WITH DOWN SYNDROME NEUROPATHOLOGY

IBRO neuroscience reports, 2023-10, Vol.15, p.S391-S391

2023

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Stress Responses in Down Syndrome Neurodegeneration: State of the Art and Therapeutic Molecules

Biomolecules (Basel, Switzerland), 2021-02, Vol.11 (2), p.266

2021

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Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome

Neurobiology of disease, 2020-04, Vol.137, p.104772-104772, Article 104772

2020

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Proteomics Study of Peripheral Blood Mononuclear Cells in Down Syndrome Children

Antioxidants, 2020-11, Vol.9 (11), p.1112

2020

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Cathepsin D as a therapeutic target in Alzheimer's disease

Expert opinion on therapeutic targets, 2016-12, Vol.20 (12), p.1393-1395

2016

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It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and UCHL1 in Alzheimer Disease

Oxidative medicine and cellular longevity, 2016-01, Vol.2016 (2016), p.1-12

2016

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Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm

Free radical biology & medicine, 2016-02, Vol.91, p.127-142

2016

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Biliverdin Reductase-A Mediates the Beneficial Effects of Intranasal Insulin in Alzheimer Disease

Molecular neurobiology, 2019-04, Vol.56 (4), p.2922-2943

2019

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Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease

Neurobiology of disease, 2019-05, Vol.125, p.176-189

2019

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Mass spectrometry and redox proteomics: Applications in disease

Mass spectrometry reviews, 2014-07, Vol.33 (4), p.277-301

2014

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Effects of UVB-induced oxidative stress on protein expression and specific protein oxidation in normal human epithelial keratinocytes: a proteomic approach

Proteome science, 2010-03, Vol.8 (1), p.13-13, Article 13

2010

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Therapeutic potential of rescuing protein O-GlcNAcylation in tau-related pathologies

Expert review of neurotherapeutics, 2019-01, Vol.19 (1), p.1-3

2019

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Shaping down syndrome brain cognitive and molecular changes due to aging using adult animals from the Ts66Yah murine model

Neurobiology of disease, 2024-06, Vol.196, p.106523-106523, Article 106523

2024

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Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients

Free radical biology & medicine, 2016-02, Vol.91, p.1-9

2016

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Biliverdin Reductase-A correlates with inducible nitric oxide synthasein in atorvastatin treated aged canine brain

Neural regeneration research, 2013-07, Vol.8 (21), p.1925-1937

2013

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Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: Redox proteomics analysis of human brain

Biochimica et biophysica acta, 2013-08, Vol.1832 (8), p.1249-1259

2013

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Redox proteomics analysis of HNE-modified proteins in Down syndrome brain: clues for understanding the development of Alzheimer disease

High-Fat Diet Leads to Reduced Protein O-GlcNAcylation and Mitochondrial Defects Promoting the Development of Alzheimer's Disease Signatures

BVR-A Deficiency Leads to Autophagy Impairment through the Dysregulation of AMPK/mTOR Axis in the Brain—Implications for Neurodegeneration

Role of 4-hydroxy-2-nonenal (HNE) in the pathogenesis of alzheimer disease and other selected age-related neurodegenerative disorders

mTOR signaling in aging and neurodegeneration: At the crossroad between metabolism dysfunction and impairment of autophagy

Glutathionylation of the Pro-apoptotic Protein p53 in Alzheimer’s Disease Brain: Implications for AD Pathogenesis

The Triangle of Death in Alzheimer's Disease Brain: The Aberrant Cross-Talk Among Energy Metabolism, Mammalian Target of Rapamycin Signaling, and Protein Homeostasis Revealed by Redox Proteomics

Statins more than cholesterol lowering agents in Alzheimer disease: Their pleiotropic functions as potential therapeutic targets

The Janus face of the heme oxygenase/biliverdin reductase system in Alzheimer disease: It's time for reconciliation

DECIPHERING THE NOXIOUS INTERPLAY BETWEEN THE UNFOLDED PROTEIN RESPONSE AND ANTIOXIDANT RESPONSES UNDER ABERRANT METABOLIC STIMULI ASSOCIATED WITH DOWN SYNDROME NEUROPATHOLOGY

Stress Responses in Down Syndrome Neurodegeneration: State of the Art and Therapeutic Molecules

Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome

Proteomics Study of Peripheral Blood Mononuclear Cells in Down Syndrome Children

Cathepsin D as a therapeutic target in Alzheimer's disease

It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and UCHL1 in Alzheimer Disease

Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm

Biliverdin Reductase-A Mediates the Beneficial Effects of Intranasal Insulin in Alzheimer Disease

Loss of biliverdin reductase-A favors Tau hyper-phosphorylation in Alzheimer's disease

Mass spectrometry and redox proteomics: Applications in disease

Effects of UVB-induced oxidative stress on protein expression and specific protein oxidation in normal human epithelial keratinocytes: a proteomic approach

Therapeutic potential of rescuing protein O-GlcNAcylation in tau-related pathologies

Shaping down syndrome brain cognitive and molecular changes due to aging using adult animals from the Ts66Yah murine model

Oxidative signature of cerebrospinal fluid from mild cognitive impairment and Alzheimer disease patients

Biliverdin Reductase-A correlates with inducible nitric oxide synthasein in atorvastatin treated aged canine brain

Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: Redox proteomics analysis of human brain

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