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A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation

Scientific reports, 2021-07, Vol.11 (1), p.15319-15319, Article 15319

2021

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PLCγ2 regulates TREM2 signalling and integrin-mediated adhesion and migration of human iPSC-derived macrophages

Scientific reports, 2021-10, Vol.11 (1), p.19842-19842, Article 19842

2021

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Author Correction: A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation

Scientific reports, 2021-10, Vol.11 (1), p.20529-20529, Article 20529

2021

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Microglial inflammation and phagocytosis in Alzheimer's disease: Potential therapeutic targets

British journal of pharmacology, 2019-09, Vol.176 (18), p.3515-3532

2019

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Inhibition of the NLRP3 inflammasome by HSP90 inhibitors

Immunology, 2021-01, Vol.162 (1), p.84-91

2021

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Inflammasome activation controlled by the interplay between post-translational modifications: emerging drug target opportunities

Cell communication and signaling, 2021-02, Vol.19 (1), p.23-12, Article 23

2021

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Oscillating Magnet Array-Based Nanomagnetic Gene Transfection: A Valuable Tool for Molecular Neurobiology Studies

Nanomaterials (Basel, Switzerland), 2017-01, Vol.7 (2), p.28-28

2017

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Comparative analysis of the effects of four mood stabilizers in SH-SY5Y cells and in primary neurons

Bipolar disorders, 2005-02, Vol.7 (1), p.33-41

2005

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Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain

Structure (London), 2021-11, Vol.29 (11), p.1241-1252.e5

2021

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Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia

Cell reports (Cambridge), 2024-05, Vol.43 (5), p.114152, Article 114152

2024

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TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages

Alzheimer's research & therapy, 2020-11, Vol.12 (1), p.151-151, Article 151

2020

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Phenotypic Knockout of Nerve Growth Factor in Adult Transgenic Mice Reveals Severe Deficits in Basal Forebrain Cholinergic Neurons, Cell Death in the Spleen, and Skeletal Muscle Dystrophy

The Journal of neuroscience, 2000-04, Vol.20 (7), p.2589-2601

2000

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Neural network dysfunction in bipolar depression: clues from the efficacy of lamotrigine

Biochemical Society transactions, 2009-10, Vol.37 (Pt 5), p.1080

2009

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Investigation of the H(+)-myo-inositol transporter (HMIT) as a neuronal regulator of phosphoinositide signalling

Biochemical Society transactions, 2009-10, Vol.37 (Pt 5), p.1139

2009

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Expression and Characterization of GSK-3 Mutants and Their Effect on β-Catenin Phosphorylation in Intact Cells

The Journal of biological chemistry, 2002-06, Vol.277 (26), p.23330-23335

2002

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Evaluation of expression and function of the H+/myo-inositol transporter HMIT

BMC cell biology, 2009-07, Vol.10, p.54

2009

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TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation

Proceedings of the National Academy of Sciences - PNAS, 2021-09, Vol.118 (38)

2021

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Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function

Autophagy, 2023-02, Vol.19 (2), p.692-705

2023

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Targeting SHIP1 for therapeutic intervention in Alzheimer’s disease: Nonhuman/Target identification and validation studies: Inflammation and innate immunity

Alzheimer's & dementia, 2020-12, Vol.16 (S9)

2020

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TREM2 Alzheimer’s variant R47H causes similar transcriptional dysregulation to TREM2 knockout in human IPSC‐derived macrophages

Alzheimer's & dementia, 2020-12, Vol.16, p.n/a

2020

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TREM2 Alzheimer’s variant R47H causes similar transcriptional dysregulation to TREM2 knockout in human IPSC‐derived macrophages: Developing topics

Alzheimer's & dementia, 2020-12, Vol.16 (S3)

2020

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Targeting SHIP1 for therapeutic intervention in Alzheimer’s disease

Alzheimer's & dementia, 2020-12, Vol.16, p.n/a

2020

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Muscular dystrophy in adult and aged anti-NGF transgenic mice resembles an inclusion body myopathy

Journal of neuroscience research, 2000-02, Vol.59 (4), p.553-560

2000

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In vitro Quantitative Imaging Assay for Phagocytosis of Dead Neuroblastoma Cells by iPSC-Macrophages

Journal of visualized experiments, 2021-02 (168)

2021

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Abnormalities in α/β-CaMKII and related mechanisms suggest synaptic dysfunction in hippocampus of LPA1 receptor knockout mice

The international journal of neuropsychopharmacology, 2011-08, Vol.14 (7), p.941-953

2011

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A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation

PLCγ2 regulates TREM2 signalling and integrin-mediated adhesion and migration of human iPSC-derived macrophages

Author Correction: A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation

Microglial inflammation and phagocytosis in Alzheimer's disease: Potential therapeutic targets

Inhibition of the NLRP3 inflammasome by HSP90 inhibitors

Inflammasome activation controlled by the interplay between post-translational modifications: emerging drug target opportunities

Oscillating Magnet Array-Based Nanomagnetic Gene Transfection: A Valuable Tool for Molecular Neurobiology Studies

Comparative analysis of the effects of four mood stabilizers in SH-SY5Y cells and in primary neurons

Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain

Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3-mediated IL-1β production in human macrophages and microglia

TREM2 Alzheimer's variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages

Phenotypic Knockout of Nerve Growth Factor in Adult Transgenic Mice Reveals Severe Deficits in Basal Forebrain Cholinergic Neurons, Cell Death in the Spleen, and Skeletal Muscle Dystrophy

Neural network dysfunction in bipolar depression: clues from the efficacy of lamotrigine

Investigation of the H(+)-myo-inositol transporter (HMIT) as a neuronal regulator of phosphoinositide signalling

Expression and Characterization of GSK-3 Mutants and Their Effect on β-Catenin Phosphorylation in Intact Cells

Evaluation of expression and function of the H+/myo-inositol transporter HMIT

TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation

Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function

Targeting SHIP1 for therapeutic intervention in Alzheimer’s disease: Nonhuman/Target identification and validation studies: Inflammation and innate immunity

TREM2 Alzheimer’s variant R47H causes similar transcriptional dysregulation to TREM2 knockout in human IPSC‐derived macrophages

TREM2 Alzheimer’s variant R47H causes similar transcriptional dysregulation to TREM2 knockout in human IPSC‐derived macrophages: Developing topics

Targeting SHIP1 for therapeutic intervention in Alzheimer’s disease

Muscular dystrophy in adult and aged anti-NGF transgenic mice resembles an inclusion body myopathy

In vitro Quantitative Imaging Assay for Phagocytosis of Dead Neuroblastoma Cells by iPSC-Macrophages

Abnormalities in α/β-CaMKII and related mechanisms suggest synaptic dysfunction in hippocampus of LPA1 receptor knockout mice

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