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Organocatalyzed, Visible-Light Photoredox-Mediated, One-Pot Minisci Reaction Using Carboxylic Acids via N‑(Acyloxy)phthalimides

Journal of organic chemistry, 2018-03, Vol.83 (5), p.3000-3012

2018

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Synthesis of Cyclobutane-Fused Tetracyclic Scaffolds via Visible-Light Photocatalysis for Building Molecular Complexity

Journal of the American Chemical Society, 2020-02, Vol.142 (6), p.3094-3103

2020

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Ligand-Promoted Borylation of C(sp3)H Bonds with Palladium(II) Catalysts

Angewandte Chemie International Edition, 2016-01, Vol.55 (2), p.785-789

International ed. in English, 2016

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Perspectives on Nuclear Magnetic Resonance Spectroscopy in Drug Discovery Research

Journal of medicinal chemistry, 2024-02, Vol.67 (3), p.1701-1733

2024

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The Routledge Encyclopedia of Indian Writing in English

1, 2023

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Photocatalytic Dearomative Intermolecular [2 + 2] Cycloaddition of Heterocycles for Building Molecular Complexity

Journal of organic chemistry, 2021-01, Vol.86 (2), p.1730-1747

2021

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Overcoming Limitations in Decarboxylative Arylation via Ag–Ni Electrocatalysis

Journal of the American Chemical Society, 2022-09, Vol.144 (38), p.17709-17720

2022

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Decarboxylative Intramolecular Arene Alkylation Using N‑(Acyloxy)phthalimides, an Organic Photocatalyst, and Visible Light

Journal of organic chemistry, 2019-07, Vol.84 (13), p.8360-8379

2019

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Advances in the synthesis of three-dimensional molecular architectures by dearomatizing photocycloadditions

Tetrahedron, 2022-01, Vol.103, p.132087, Article 132087

2022

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Synthesis of 1‑(tert-Butyl) 4‑Methyl (1R,2S,4R)‑2-Methylcyclohexane-1,4-dicarboxylate from Hagemann’s tert-Butyl Ester for an Improved Synthesis of BMS-986251

Journal of organic chemistry, 2020-08, Vol.85 (16), p.10988-10993

2020

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Complex molecule synthesis by electrocatalytic decarboxylative cross-coupling

Nature (London), 2023-11, Vol.623 (7988), p.745-751

2023

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RORγt Represses IL-10 Production in Th17 Cells To Maintain Their Pathogenicity in Inducing Intestinal Inflammation

The Journal of immunology (1950), 2019-01, Vol.202 (1), p.79-92

2019

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Intramolecular [2+2] Cycloaddition of N‐Allylcinnamamines and N‐Allylcinnamamides by Visible‐Light Photocatalysis

European journal of organic chemistry, 2020-01, Vol.2020 (1), p.41-46

2020

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Annulation reaction enables the identification of an exocyclic amide tricyclic chemotype as retinoic acid Receptor-Related orphan receptor gamma (RORγ/RORc) inverse agonists

Bioorganic & medicinal chemistry letters, 2020-10, Vol.30 (19), p.127466-127466, Article 127466

2020

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One-Step Diastereoselective Pyrrolidine Synthesis Using a Sulfinamide Annulating Reagent

Organic letters, 2019-11, Vol.21 (22), p.9198-9202

2019

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Biologic-like In Vivo Efficacy with Small Molecule Inhibitors of TNFα Identified Using Scaffold Hopping and Structure-Based Drug Design Approaches

Journal of medicinal chemistry, 2020-12, Vol.63 (23), p.15050-15071

2020

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Tricyclic-Carbocyclic RORγt Inverse AgonistsDiscovery of BMS-986313

Journal of medicinal chemistry, 2021-03, Vol.64 (5), p.2714-2724

2021

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Rationally Designed, Conformationally Constrained Inverse Agonists of RORγtIdentification of a Potent, Selective Series with Biologic-Like in Vivo Efficacy

Journal of medicinal chemistry, 2019-11, Vol.62 (21), p.9931-9946

2019

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Discovery of Annulating Reagents Enabling the One-Step and Highly Stereoselective Synthesis of Cyclopentyl and Cyclohexyl Cores

Organic letters, 2021-01, Vol.23 (1), p.60-65

2021

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Discovery of (3S,4S)-3-methyl-3-(4-fluorophenyl)-4-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxyprop-2-yl)phenyl)pyrrolidines as novel RORγt inverse agonists

Bioorganic & medicinal chemistry letters, 2020-09, Vol.30 (17), p.127392-127392, Article 127392

2020

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Protected Chloroethyl and Chloropropyl Amines as Conformationally Unrestricted Annulating Reagents

Organic letters, 2018-01, Vol.20 (2), p.337-340

2018

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Unlocking Tertiary Acids for Metallaphotoredox C(sp2)–C(sp3) Decarboxylative Cross-Couplings

ACS catalysis, 2023-09, Vol.13 (18), p.11910-11918

2023

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Identification of potent, selective and orally bioavailable phenyl ((R)-3-phenylpyrrolidin-3-yl)sulfone analogues as RORγt inverse agonists

Bioorganic & medicinal chemistry letters, 2019-08, Vol.29 (16), p.2265-2269

2019

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Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORγt Inverse Agonists

ACS medicinal chemistry letters, 2019-03, Vol.10 (3), p.367-373

2019

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Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity

Bioorganic & medicinal chemistry letters, 2018-01, Vol.28 (2), p.85-93

2018

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Organocatalyzed, Visible-Light Photoredox-Mediated, One-Pot Minisci Reaction Using Carboxylic Acids via N‑(Acyloxy)phthalimides

Synthesis of Cyclobutane-Fused Tetracyclic Scaffolds via Visible-Light Photocatalysis for Building Molecular Complexity

Ligand-Promoted Borylation of C(sp3)H Bonds with Palladium(II) Catalysts

Perspectives on Nuclear Magnetic Resonance Spectroscopy in Drug Discovery Research

The Routledge Encyclopedia of Indian Writing in English

Photocatalytic Dearomative Intermolecular [2 + 2] Cycloaddition of Heterocycles for Building Molecular Complexity

Overcoming Limitations in Decarboxylative Arylation via Ag–Ni Electrocatalysis

Decarboxylative Intramolecular Arene Alkylation Using N‑(Acyloxy)phthalimides, an Organic Photocatalyst, and Visible Light

Advances in the synthesis of three-dimensional molecular architectures by dearomatizing photocycloadditions

Synthesis of 1‑(tert-Butyl) 4‑Methyl (1R,2S,4R)‑2-Methylcyclohexane-1,4-dicarboxylate from Hagemann’s tert-Butyl Ester for an Improved Synthesis of BMS-986251

Complex molecule synthesis by electrocatalytic decarboxylative cross-coupling

RORγt Represses IL-10 Production in Th17 Cells To Maintain Their Pathogenicity in Inducing Intestinal Inflammation

Intramolecular [2+2] Cycloaddition of N‐Allylcinnamamines and N‐Allylcinnamamides by Visible‐Light Photocatalysis

Annulation reaction enables the identification of an exocyclic amide tricyclic chemotype as retinoic acid Receptor-Related orphan receptor gamma (RORγ/RORc) inverse agonists

One-Step Diastereoselective Pyrrolidine Synthesis Using a Sulfinamide Annulating Reagent

Biologic-like In Vivo Efficacy with Small Molecule Inhibitors of TNFα Identified Using Scaffold Hopping and Structure-Based Drug Design Approaches

Tricyclic-Carbocyclic RORγt Inverse AgonistsDiscovery of BMS-986313

Rationally Designed, Conformationally Constrained Inverse Agonists of RORγtIdentification of a Potent, Selective Series with Biologic-Like in Vivo Efficacy

Discovery of Annulating Reagents Enabling the One-Step and Highly Stereoselective Synthesis of Cyclopentyl and Cyclohexyl Cores

Discovery of (3S,4S)-3-methyl-3-(4-fluorophenyl)-4-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxyprop-2-yl)phenyl)pyrrolidines as novel RORγt inverse agonists

Protected Chloroethyl and Chloropropyl Amines as Conformationally Unrestricted Annulating Reagents

Unlocking Tertiary Acids for Metallaphotoredox C(sp2)–C(sp3) Decarboxylative Cross-Couplings

Identification of potent, selective and orally bioavailable phenyl ((R)-3-phenylpyrrolidin-3-yl)sulfone analogues as RORγt inverse agonists

Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORγt Inverse Agonists

Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity

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