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Morphine decreases enteric neuron excitability via inhibition of sodium channels

PloS one, 2012-09, Vol.7 (9), p.e45251

2012

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Lysosomal cholesterol accumulation in macrophages leading to coronary atherosclerosis in CD38−/− mice

Journal of cellular and molecular medicine, 2016-06, Vol.20 (6), p.1001-1013

2016

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Tolerance to Morphine-Induced Inhibition of TTX-R Sodium Channels in Dorsal Root Ganglia Neurons Is Modulated by Gut-Derived Mediators

iScience, 2018-04, Vol.2, p.193-209

2018

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Morphine efficacy is altered in conditional HIV-1 Tat transgenic mice

European journal of pharmacology, 2012-08, Vol.689 (1-3), p.96-103

2012

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Morphine tolerance in the mouse ileum and colon

The Journal of pharmacology and experimental therapeutics, 2008-11, Vol.327 (2), p.561-572

2008

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Gastrointestinal motility, dysbiosis and opioid-induced tolerance: is there a link?

Nature reviews. Gastroenterology & hepatology, 2019-06, Vol.16 (6), p.323-324

2019

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The gut–brain interaction in opioid tolerance

Current opinion in pharmacology, 2017-12, Vol.37, p.126-130

2017

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Specific localization of β-Arrestin2 in myenteric plexus of mouse gastrointestinal tract

PloS one, 2014-08, Vol.9 (8), p.e103894

2014

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Oxycodone‐induced tolerance to respiratory depression: reversal by ethanol, pregabalin and protein kinase C inhibition

British journal of pharmacology, 2018-06, Vol.175 (12), p.2492-2503

2018

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The effect of gut microbiome on tolerance to morphine mediated antinociception in mice

Scientific reports, 2017-02, Vol.7 (1), p.42658, Article 42658

2017

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Role of β-arrestin-2 in short- and long-term opioid tolerance in the dorsal root ganglia

European journal of pharmacology, 2021-05, Vol.899, p.174007-174007, Article 174007

2021

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μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization

Molecular pharmacology, 2010-10, Vol.78 (4), p.756-766

2010

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Determination of the role of conventional, novel and atypical PKC isoforms in the expression of morphine tolerance in mice

Pain (Amsterdam), 2007, Vol.127 (1), p.129-139

2007

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Experimental Colitis Enhances the Rate of Antinociceptive Tolerance to Morphine via Peripheral Opioid Receptors

The Journal of pharmacology and experimental therapeutics, 2019-09, Vol.370 (3), p.504-513

2019

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Systematic Structure–Activity Relationship Study of Nalfurafine Analogues toward Development of Potentially Nonaddictive Pain Management Treatments

Journal of medicinal chemistry, 2024-06, Vol.67 (11), p.9552-9574

2024

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Evidence for the Putative Cannabinoid Receptor (GPR55)-Mediated Inhibitory Effects on Intestinal Contractility in Mice

Pharmacology, 2012-01, Vol.90 (1-2), p.55-65

2012

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The role of morphine‐ and fentanyl‐induced impairment of intestinal epithelial antibacterial activity in dysbiosis and its impact on the microbiota‐gut‐brain axis

The FASEB journal, 2024-04, Vol.38 (8), p.e23603-n/a

2024

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Rational Design, Chemical Syntheses, and Biological Evaluations of Peripherally Selective Mu Opioid Receptor Ligands as Potential Opioid Induced Constipation Treatment

Journal of medicinal chemistry, 2022-03, Vol.65 (6), p.4991-5003

2022

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Correction: Morphine Decreases Enteric Neuron Excitability via Inhibition of Sodium Channels

PloS one, 2013-05, Vol.8 (5)

2013

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Structural Alterations of the “Address” Moiety of NAN Leading to the Discovery of a Novel Opioid Receptor Modulator with Reduced hERG Toxicity

Journal of medicinal chemistry, 2023-01, Vol.66 (1), p.577-595

2023

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The Selective Monoacylglycerol Lipase Inhibitor MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model

The Journal of pharmacology and experimental therapeutics, 2016-04, Vol.357 (1), p.145-156

2016

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Connexin‐purinergic signaling in enteric glia mediates the prolonged effect of morphine on constipation

The FASEB journal, 2017-06, Vol.31 (6), p.2649-2660

2017

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The Guts of the Opioid Crisis

Physiology (Bethesda, Md.), 2021-09, Vol.36 (5), p.315-323

2021

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Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists

Journal of medicinal chemistry, 2022-03, Vol.65 (6), p.5095-5112

2022

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CCR5 mediates HIV-1 Tat-induced neuroinflammation and influences morphine tolerance, dependence, and reward

Brain, behavior, and immunity, 2018-03, Vol.69, p.124-138

2018

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Morphine decreases enteric neuron excitability via inhibition of sodium channels

Lysosomal cholesterol accumulation in macrophages leading to coronary atherosclerosis in CD38−/− mice

Tolerance to Morphine-Induced Inhibition of TTX-R Sodium Channels in Dorsal Root Ganglia Neurons Is Modulated by Gut-Derived Mediators

Morphine efficacy is altered in conditional HIV-1 Tat transgenic mice

Morphine tolerance in the mouse ileum and colon

Gastrointestinal motility, dysbiosis and opioid-induced tolerance: is there a link?

The gut–brain interaction in opioid tolerance

Specific localization of β-Arrestin2 in myenteric plexus of mouse gastrointestinal tract

Oxycodone‐induced tolerance to respiratory depression: reversal by ethanol, pregabalin and protein kinase C inhibition

The effect of gut microbiome on tolerance to morphine mediated antinociception in mice

Role of β-arrestin-2 in short- and long-term opioid tolerance in the dorsal root ganglia

μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization

Determination of the role of conventional, novel and atypical PKC isoforms in the expression of morphine tolerance in mice

Experimental Colitis Enhances the Rate of Antinociceptive Tolerance to Morphine via Peripheral Opioid Receptors

Systematic Structure–Activity Relationship Study of Nalfurafine Analogues toward Development of Potentially Nonaddictive Pain Management Treatments

Evidence for the Putative Cannabinoid Receptor (GPR55)-Mediated Inhibitory Effects on Intestinal Contractility in Mice

The role of morphine‐ and fentanyl‐induced impairment of intestinal epithelial antibacterial activity in dysbiosis and its impact on the microbiota‐gut‐brain axis

Rational Design, Chemical Syntheses, and Biological Evaluations of Peripherally Selective Mu Opioid Receptor Ligands as Potential Opioid Induced Constipation Treatment

Correction: Morphine Decreases Enteric Neuron Excitability via Inhibition of Sodium Channels

Structural Alterations of the “Address” Moiety of NAN Leading to the Discovery of a Novel Opioid Receptor Modulator with Reduced hERG Toxicity

The Selective Monoacylglycerol Lipase Inhibitor MJN110 Produces Opioid-Sparing Effects in a Mouse Neuropathic Pain Model

Connexin‐purinergic signaling in enteric glia mediates the prolonged effect of morphine on constipation

The Guts of the Opioid Crisis

Design, Synthesis, and Biological Evaluation of NAP Isosteres: A Switch from Peripheral to Central Nervous System Acting Mu-Opioid Receptor Antagonists

CCR5 mediates HIV-1 Tat-induced neuroinflammation and influences morphine tolerance, dependence, and reward

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