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Mitochondria at the neuronal presynapse in health and disease

Nature reviews. Neuroscience, 2018-02, Vol.19 (2), p.63-80

2018

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α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease

Nature communications, 2018-06, Vol.9 (1), p.2293-16, Article 2293

2018

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Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

Cell death and differentiation, 2020-10, Vol.27 (10), p.2781-2796

2020

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Miro1‐dependent mitochondrial positioning drives the rescaling of presynaptic Ca2+ signals during homeostatic plasticity

EMBO reports, 2017-02, Vol.18 (2), p.231-240

2017

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Miro sculpts mitochondrial dynamics in neuronal health and disease

Neurobiology of disease, 2016-06, Vol.90, p.27-34

2016

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A cell culture model for monitoring α-synuclein cell-to-cell transfer

Neurobiology of disease, 2015-05, Vol.77 (Jul 16), p.266-275

2015

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Rapamycin regulates autophagy and cell adhesion in induced pluripotent stem cells

Stem cell research & therapy, 2016-11, Vol.7 (1), p.166-16, Article 166

2016

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Characterization of two human induced pluripotent stem cell lines derived from Batten disease patient fibroblasts harbouring CLN5 mutations

Stem cell research, 2024-02, Vol.74, p.103291-103291, Article 103291

2024

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Pathogenic Parkinson’s disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation

Biochemical and biophysical research communications, 2013-11, Vol.441 (4), p.862-866

2013

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The role of the right inferior frontal gyrus in the pathogenesis of post-stroke psychosis

Journal of neurology, 2014-03, Vol.261 (3), p.600-603

2014

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α-Synuclein binds to the ER–mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP production

Acta neuropathologica, 2017-07, Vol.134 (1), p.129-149

2017

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Using stem cell–derived neurons in drug screening for neurological diseases

Neurobiology of aging, 2019-06, Vol.78, p.130-141

2019

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Parkinson's disease and α-synuclein expression

Movement disorders, 2011-10, Vol.26 (12), p.2160-2168

2011

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Nanoscale tweezers for single-cell biopsies

Nature nanotechnology, 2019-01, Vol.14 (1), p.80-88

2019

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Parkinson's disease and cancer: two wars, one front

Nature reviews. Cancer, 2011-11, Vol.11 (11), p.812-823

2011

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Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease

Antioxidants & redox signaling, 2016-03, Vol.24 (7), p.376-391

2016

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Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus

Nature communications, 2011-08, Vol.2 (1), p.440-440, Article 440

2011

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Generation of human pluripotent stem cell reporter lines for the isolation of and reporting on astrocytes generated from ventral midbrain and ventral spinal cord neural progenitors

Stem cell research, 2015-07, Vol.15 (1), p.203-220

2015

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Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPT

Human molecular genetics, 2015-09, Vol.24 (18), p.5260-5269

2015

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Mitochondrial Ca2+ uniporter haploinsufficiency enhances long-term potentiation at hippocampal mossy fibre synapses

Journal of cell science, 2022-11, Vol.135 (22)

2022

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Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissue

PloS one, 2011-07, Vol.6 (7), p.e22489-e22489

2011

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Proteasomal inhibition as a treatment strategy for Parkinson's disease: the impact of α-synuclein on Nurr1

The Journal of neuroscience, 2012-11, Vol.32 (46), p.16071-16073

Devine, Michael J

2012

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The V-ATPase/ATG16L1 axis is controlled by the V1H subunit

Molecular cell, 2024-08, Vol.84 (15), p.2966-2983.e9

2024

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A single cell high content assay detects mitochondrial dysfunction in iPSC-derived neurons with mutations in SNCA

Scientific reports, 2018-06, Vol.8 (1), p.9033-16, Article 9033

2018

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High-Content Analysis of Mitochondrial Function in iPSC-Derived Neurons

Methods in molecular biology (Clifton, N.J.), 2019, Vol.1994, p.175

2019

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Mitochondria at the neuronal presynapse in health and disease

α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease

Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

Miro1‐dependent mitochondrial positioning drives the rescaling of presynaptic Ca2+ signals during homeostatic plasticity

Miro sculpts mitochondrial dynamics in neuronal health and disease

A cell culture model for monitoring α-synuclein cell-to-cell transfer

Rapamycin regulates autophagy and cell adhesion in induced pluripotent stem cells

Characterization of two human induced pluripotent stem cell lines derived from Batten disease patient fibroblasts harbouring CLN5 mutations

Pathogenic Parkinson’s disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation

The role of the right inferior frontal gyrus in the pathogenesis of post-stroke psychosis

α-Synuclein binds to the ER–mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP production

Using stem cell–derived neurons in drug screening for neurological diseases

Parkinson's disease and α-synuclein expression

Nanoscale tweezers for single-cell biopsies

Parkinson's disease and cancer: two wars, one front

Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease

Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus

Generation of human pluripotent stem cell reporter lines for the isolation of and reporting on astrocytes generated from ventral midbrain and ventral spinal cord neural progenitors

Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPT

Mitochondrial Ca2+ uniporter haploinsufficiency enhances long-term potentiation at hippocampal mossy fibre synapses

Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissue

Proteasomal inhibition as a treatment strategy for Parkinson's disease: the impact of α-synuclein on Nurr1

The V-ATPase/ATG16L1 axis is controlled by the V1H subunit

A single cell high content assay detects mitochondrial dysfunction in iPSC-derived neurons with mutations in SNCA

High-Content Analysis of Mitochondrial Function in iPSC-Derived Neurons

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