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Translation Elongation and Recoding in Eukaryotes

Cold Spring Harbor perspectives in biology, 2018-08, Vol.10 (8), p.a032649

2018

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eIF5A Promotes Translation of Polyproline Motifs

Molecular cell, 2013-07, Vol.51 (1), p.35-45

2013

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eIF5A Functions Globally in Translation Elongation and Termination

Molecular cell, 2017-04, Vol.66 (2), p.194-205.e5

2017

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Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae

Genetics (Austin), 2016-05, Vol.203 (1), p.65-107

2016

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Hypusine-containing protein eIF5A promotes translation elongation

Nature, 2009-05, Vol.459 (7243), p.118-121

2009

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An eIF2α-binding motif in protein phosphatase 1 subunit GADD34 and its viral orthologs is required to promote dephosphorylation of eIF2α

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (27), p.E3466-E3475

2015

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Polyamine Control of Translation Elongation Regulates Start Site Selection on Antizyme Inhibitor mRNA via Ribosome Queuing

Molecular cell, 2018-04, Vol.70 (2), p.254-264.e6

2018

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The hypusine-containing translation factor eIF5A

Critical reviews in biochemistry and molecular biology, 2014-09, Vol.49 (5), p.413-425

2014

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eEF2 diphthamide modification restrains spurious frameshifting to maintain translational fidelity

Nucleic acids research, 2023-07, Vol.51 (13), p.6899

2023

Volltextzugriff (PDF)

Biochemical mechanisms for translational regulation in synaptic plasticity

Nature reviews. Neuroscience, 2004-12, Vol.5 (12), p.931-942

2004

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Amino acid substrates impose polyamine, eIF5A, or hypusine requirement for peptide synthesis

Nucleic acids research, 2017-08, Vol.45 (14), p.8392

2017

Volltextzugriff (PDF)

Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA Splicing

Cell, 2008-01, Vol.132 (1), p.89-100

2008

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Structural basis for the transition from translation initiation to elongation by an 80S-eIF5B complex

Nature communications, 2020-10, Vol.11 (1), p.5003-5003, Article 5003

2020

Volltextzugriff (PDF)

Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome

Journal of molecular biology, 2016-09, Vol.428 (18), p.3570-3576

2016

Volltextzugriff (PDF)

eIF2γ Mutation that Disrupts eIF2 Complex Integrity Links Intellectual Disability to Impaired Translation Initiation

Molecular cell, 2012-11, Vol.48 (4), p.641-646

2012

Volltextzugriff (PDF)

Structural characterization of ribosome recruitment and translocation by type IV IRES

eLife, 2016-05, Vol.5

2016

Volltextzugriff (PDF)

Eukaryotic translation initiation factors and regulators

Current opinion in structural biology, 2003-02, Vol.13 (1), p.56-63

2003

Volltextzugriff (PDF)

Translation Elongation and Recoding in Eukaryotes

Cold Spring Harbor perspectives in biology, 2018-08, Vol.10 (8)

2018

Volltextzugriff (PDF)

Protein phosphatase PP1/GLC7 interaction domain in yeast eIF2γ bypasses targeting subunit requirement for eIF2α dephosphorylation

Proceedings of the National Academy of Sciences - PNAS, 2014-04, Vol.111 (14), p.E1344-E1353

2014

Volltextzugriff (PDF)

PK4, a eukaryotic initiation factor 2α(eIF2α) kinase, is essential for the development of the erythrocytic cycle of Plasmodium

Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (10), p.3956-3961

2012

Volltextzugriff (PDF)

Enhanced interaction between pseudokinase and kinase domains in Gcn2 stimulates eIF2α phosphorylation in starved cells

PLoS genetics, 2014-05, Vol.10 (5), p.e1004326-e1004326

2014

Volltextzugriff (PDF)

Rapid evolution of protein kinase PKR alters sensitivity to viral inhibitors

Nature structural & molecular biology, 2009-01, Vol.16 (1), p.63-70

2009

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Roles of polyamines in translation

The Journal of biological chemistry, 2018-11, Vol.293 (48), p.18719-18729

2018

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The elongation, termination, and recycling phases of translation in eukaryotes

Cold Spring Harbor perspectives in biology, 2012-07, Vol.4 (7), p.a013706-a013706

2012

Volltextzugriff (PDF)

The β-hairpin of 40S exit channel protein Rps5/uS7 promotes efficient and accurate translation initiation in vivo

eLife, 2015-07, Vol.4, p.e07939-e07939

2015

Volltextzugriff (PDF)

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Saccharomyces Cerevisiae - Genetics
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Translation Elongation and Recoding in Eukaryotes

eIF5A Promotes Translation of Polyproline Motifs

eIF5A Functions Globally in Translation Elongation and Termination

Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae

Hypusine-containing protein eIF5A promotes translation elongation

An eIF2α-binding motif in protein phosphatase 1 subunit GADD34 and its viral orthologs is required to promote dephosphorylation of eIF2α

Polyamine Control of Translation Elongation Regulates Start Site Selection on Antizyme Inhibitor mRNA via Ribosome Queuing

The hypusine-containing translation factor eIF5A

eEF2 diphthamide modification restrains spurious frameshifting to maintain translational fidelity

Biochemical mechanisms for translational regulation in synaptic plasticity

Amino acid substrates impose polyamine, eIF5A, or hypusine requirement for peptide synthesis

Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA Splicing

Structural basis for the transition from translation initiation to elongation by an 80S-eIF5B complex

Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome

eIF2γ Mutation that Disrupts eIF2 Complex Integrity Links Intellectual Disability to Impaired Translation Initiation

Structural characterization of ribosome recruitment and translocation by type IV IRES

Eukaryotic translation initiation factors and regulators

Translation Elongation and Recoding in Eukaryotes

Protein phosphatase PP1/GLC7 interaction domain in yeast eIF2γ bypasses targeting subunit requirement for eIF2α dephosphorylation

PK4, a eukaryotic initiation factor 2α(eIF2α) kinase, is essential for the development of the erythrocytic cycle of Plasmodium

Enhanced interaction between pseudokinase and kinase domains in Gcn2 stimulates eIF2α phosphorylation in starved cells

Rapid evolution of protein kinase PKR alters sensitivity to viral inhibitors

Roles of polyamines in translation

The elongation, termination, and recycling phases of translation in eukaryotes

The β-hairpin of 40S exit channel protein Rps5/uS7 promotes efficient and accurate translation initiation in vivo

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