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Residue mutations and their impact on protein structure and function: detecting beneficial and pathogenic changes

Biochemical journal, 2013-02, Vol.449 (3), p.581-594

2013

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Transient Protein-Protein Interactions: Structural, Functional, and Network Properties

Structure (London), 2010-10, Vol.18 (10), p.1233-1243

2010

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Benchmarking network propagation methods for disease gene identification

PLoS computational biology, 2019-09, Vol.15 (9), p.e1007276-e1007276

2019

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New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures

Nucleic acids research, 2013-01, Vol.41 (Database issue), p.D490-D498

2013

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The chemotherapeutic agent DMXAA as a unique IRF3-dependent type-2 vaccine adjuvant

PloS one, 2013-03, Vol.8 (3), p.e60038-e60038

2013

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Gene3D: a domain-based resource for comparative genomics, functional annotation and protein network analysis

Nucleic acids research, 2012-01, Vol.40 (Database issue), p.D465-D471

2012

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Integrated pathway clusters with coherent biological themes for target prioritisation

PloS one, 2014-06, Vol.9 (6), p.e99030-e99030

2014

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Gene3D: Multi-domain annotations for protein sequence and comparative genome analysis

Nucleic acids research, 2014-01, Vol.42 (Database issue), p.D240-D245

2014

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Exploring the structure and function paradigm

Current opinion in structural biology, 2008-06, Vol.18 (3), p.394-402

2008

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Functional site plasticity in domain superfamilies

Biochimica et biophysica acta, 2013-05, Vol.1834 (5), p.874-889

2013

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Evolutionary history of the TBP-domain superfamily

Nucleic acids research, 2013-03, Vol.41 (5), p.2832-2845

2013

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LigASite--a database of biologically relevant binding sites in proteins with known apo-structures

Nucleic acids research, 2008-01, Vol.36 (Database issue), p.D667-D673

2008

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PSI-2: Structural Genomics to Cover Protein Domain Family Space

Structure (London), 2009-06, Vol.17 (6), p.869-881

2009

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Detailed Analysis of Function Divergence in a Large and Diverse Domain Superfamily: Toward a Refined Protocol of Function Classification

Structure (London), 2010-11, Vol.18 (11), p.1522-1535

2010

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Rigid-body Ligand Recognition Drives Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Receptor Triggering

The Journal of biological chemistry, 2011-02, Vol.286 (8), p.6685-6696

2011

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FLORA: a novel method to predict protein function from structure in diverse superfamilies

PLoS computational biology, 2009-08, Vol.5 (8), p.e1000485

2009

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Target selection for structural genomics of infectious diseases

Methods in molecular biology (Clifton, N.J.), 2014-01, Vol.1140, p.35

2014

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Relating destabilizing regions to known functional sites in proteins

BMC bioinformatics, 2007-04, Vol.8 (1), p.141-141, Article 141

2007

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Exploiting structural classifications for function prediction: towards a domain grammar for protein function

Current opinion in structural biology, 2009-06, Vol.19 (3), p.349-356

2009

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The evolution of protein functions and networks: a family-centric approach

Biochemical Society transactions, 2009-08, Vol.37 (Pt 4), p.745-750

2009

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Assessing functional novelty of PSI structures via structure-function analysis of large and diverse superfamilies

Nature precedings, 2008-08

2008

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Detailed Analysis of Function Divergence in a Large and Diverse Domain Superfamily: Towards a Refined Protocol of Function Classification

Structure (London), 2010-11, Vol.18 (11), p.1522-1535

2010

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Functional Diversity of the HUP Domain Superfamily

Protein Families, 2013, p.159-189

2013

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Rigid-body Ligand Recognition Drives Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Receptor Triggering<inline-graphic xlink:href="sbox.jpg"/>

The Journal of biological chemistry, 2010-12, Vol.286 (8), p.6685-6696

2010

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The Chemotherapeutic Agent DMXAA as a Unique IRF3-Dependent Type-2 Vaccine Adjuvant. e60038

PloS one, 2013-03, Vol.8 (3)

2013

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Residue mutations and their impact on protein structure and function: detecting beneficial and pathogenic changes

Transient Protein-Protein Interactions: Structural, Functional, and Network Properties

Benchmarking network propagation methods for disease gene identification

New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures

The chemotherapeutic agent DMXAA as a unique IRF3-dependent type-2 vaccine adjuvant

Gene3D: a domain-based resource for comparative genomics, functional annotation and protein network analysis

Integrated pathway clusters with coherent biological themes for target prioritisation

Gene3D: Multi-domain annotations for protein sequence and comparative genome analysis

Exploring the structure and function paradigm

Functional site plasticity in domain superfamilies

Evolutionary history of the TBP-domain superfamily

LigASite--a database of biologically relevant binding sites in proteins with known apo-structures

PSI-2: Structural Genomics to Cover Protein Domain Family Space

Detailed Analysis of Function Divergence in a Large and Diverse Domain Superfamily: Toward a Refined Protocol of Function Classification

Rigid-body Ligand Recognition Drives Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Receptor Triggering

FLORA: a novel method to predict protein function from structure in diverse superfamilies

Target selection for structural genomics of infectious diseases

Relating destabilizing regions to known functional sites in proteins

Exploiting structural classifications for function prediction: towards a domain grammar for protein function

The evolution of protein functions and networks: a family-centric approach

Assessing functional novelty of PSI structures via structure-function analysis of large and diverse superfamilies

Detailed Analysis of Function Divergence in a Large and Diverse Domain Superfamily: Towards a Refined Protocol of Function Classification

Functional Diversity of the HUP Domain Superfamily

Rigid-body Ligand Recognition Drives Cytotoxic T-lymphocyte Antigen 4 (CTLA-4) Receptor Triggering<inline-graphic xlink:href="sbox.jpg"/>

The Chemotherapeutic Agent DMXAA as a Unique IRF3-Dependent Type-2 Vaccine Adjuvant. e60038

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