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From Inhibition to Degradation: Targeting the Antiapoptotic Protein Myeloid Cell Leukemia 1 (MCL1)

Journal of medicinal chemistry, 2019-06, Vol.62 (11), p.5522-5540

2019

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Rapid synthesis of pomalidomide-conjugates for the development of protein degrader libraries

Chemical science (Cambridge), 2021-04, Vol.12 (12), p.4519-4525

2021

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Beyond geminal diesters: increasing the scope of metal-mediated vinylcyclopropane annulations while decreasing pre-activation

Organic & biomolecular chemistry, 2018, Vol.16 (19), p.356-3523

2018

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macroH2A2 antagonizes epigenetic programs of stemness in glioblastoma

Nature communications, 2023-05, Vol.14 (1), p.3062-22, Article 3062

2023

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Pannexin-1 channel inhibition alleviates opioid withdrawal in rodents by modulating locus coeruleus to spinal cord circuitry

Nature communications, 2024-07, Vol.15 (1), p.6264-17, Article 6264

2024

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Generation of Benzyne Species from Diphenylphosphoryl Derivatives: Simultaneous Exchange of Three Functional Groups

Chemistry : a European journal, 2016-06, Vol.22 (25), p.8479-8482

2016

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Natural-Product-Derived Transient Receptor Potential Melastatin 8 (TRPM8) Channel Modulators

Organic letters, 2016-06, Vol.18 (11), p.2746-2749

2016

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Leveraging Pyrazolium Ylide Reactivity to Access Indolizine and 1,2‐Dihydropyrimidine Derivatives

Chemistry : a European journal, 2024-05, Vol.30 (28), p.e202400421-n/a

2024

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Metformin Prevents Hyperglycemia-Associated, Oxidative Stress-Induced Vascular Endothelial Dysfunction: Essential Role for the Orphan Nuclear Receptor Human Nuclear Receptor 4A1 (Nur77)

Molecular pharmacology, 2021-11, Vol.100 (5), p.428-455

2021

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Pannexin 1 Channels as a Therapeutic Target: Structure, Inhibition, and Outlook

ACS chemical neuroscience, 2020-08, Vol.11 (15), p.2163-2172

2020

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ADAM protease inhibition overcomes resistance of breast cancer stem-like cells to γδ T cell immunotherapy

Cancer letters, 2021-01, Vol.496, p.156-168

2021

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Utilising the intrinsic fluorescence of pomalidomide for imaging applications

Chemical communications (Cambridge, England), 2023-12, Vol.59 (98), p.14532-14535

2023

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Regioselective Synthesis of C3-Hydroxyarylated Pyrazoles

Journal of organic chemistry, 2022-01, Vol.87 (1), p.846-854

2022

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A vinylogous Norrish reaction as a strategy for light-mediated ring expansion

Chemical communications (Cambridge, England), 2022-02, Vol.58 (17), p.291-2913

2022

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Hydrophobic Interactions as Substitutes for a Conserved Disulfide Linkage in the Type IIa Bacteriocins, Leucocin A and Pediocin PA-1

Chembiochem : a European journal of chemical biology, 2008-08, Vol.9 (12), p.1898-1901

2008

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Development of Tetrahydroquinoline-Based Inhibitors for Chronic Pain

ACS chemical neuroscience, 2024-10, Vol.15 (20), p.3704-3712

2024

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Divergent Photocyclization/1,4-Sigmatropic Rearrangements for the Synthesis of Sesquiterpenoid Derivatives

Organic letters, 2017-02, Vol.19 (3), p.484-487

2017

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Thiaporphyrin-mediated photocatalysis using red light

RSC advances, 2016-01, Vol.6 (64), p.59269-59272

2016

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Synthesis and evaluation of anti-inflammatory activity of derivatives of the marine natural products fuscol and eunicol

Bioorganic & medicinal chemistry letters, 2014-10, Vol.24 (20), p.4804-4806

2014

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Identification of ligand linkage vectors for the development of p300/CBP degraders

RSC medicinal chemistry, 2022-06, Vol.13 (6), p.726-73

2022

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Inhibition of serine and proline racemases by substrate-product analogues

Bioorganic & medicinal chemistry letters, 2014-01, Vol.24 (1), p.390-393

2014

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Photolysis of Diacyl Peroxides: A Radical-Based Approach for the Synthesis of Functionalized Amino Acids

Organic letters, 2003-08, Vol.5 (16), p.2963-2965

2003

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Antimicrobial Leucocin Analogues with a Disulfide Bridge Replaced by a Carbocycle or by Noncovalent Interactions of Allyl Glycine Residues

Journal of the American Chemical Society, 2006-11, Vol.128 (44), p.14252-14253

2006

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Preparation and Use of Cysteine Orthoesters for Solid-Supported Synthesis of Peptides

Organic letters, 2010-05, Vol.12 (10), p.2282-2285

2010

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Elucidating absolute configuration of unsaturated alcohols via enantioselective acylation reactions

Organic & biomolecular chemistry, 2013-06, Vol.11 (21), p.3432-3435

2013

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From Inhibition to Degradation: Targeting the Antiapoptotic Protein Myeloid Cell Leukemia 1 (MCL1)

Rapid synthesis of pomalidomide-conjugates for the development of protein degrader libraries

Beyond geminal diesters: increasing the scope of metal-mediated vinylcyclopropane annulations while decreasing pre-activation

macroH2A2 antagonizes epigenetic programs of stemness in glioblastoma

Pannexin-1 channel inhibition alleviates opioid withdrawal in rodents by modulating locus coeruleus to spinal cord circuitry

Generation of Benzyne Species from Diphenylphosphoryl Derivatives: Simultaneous Exchange of Three Functional Groups

Natural-Product-Derived Transient Receptor Potential Melastatin 8 (TRPM8) Channel Modulators

Leveraging Pyrazolium Ylide Reactivity to Access Indolizine and 1,2‐Dihydropyrimidine Derivatives

Metformin Prevents Hyperglycemia-Associated, Oxidative Stress-Induced Vascular Endothelial Dysfunction: Essential Role for the Orphan Nuclear Receptor Human Nuclear Receptor 4A1 (Nur77)

Pannexin 1 Channels as a Therapeutic Target: Structure, Inhibition, and Outlook

ADAM protease inhibition overcomes resistance of breast cancer stem-like cells to γδ T cell immunotherapy

Utilising the intrinsic fluorescence of pomalidomide for imaging applications

Regioselective Synthesis of C3-Hydroxyarylated Pyrazoles

A vinylogous Norrish reaction as a strategy for light-mediated ring expansion

Hydrophobic Interactions as Substitutes for a Conserved Disulfide Linkage in the Type IIa Bacteriocins, Leucocin A and Pediocin PA-1

Development of Tetrahydroquinoline-Based Inhibitors for Chronic Pain

Divergent Photocyclization/1,4-Sigmatropic Rearrangements for the Synthesis of Sesquiterpenoid Derivatives

Thiaporphyrin-mediated photocatalysis using red light

Synthesis and evaluation of anti-inflammatory activity of derivatives of the marine natural products fuscol and eunicol

Identification of ligand linkage vectors for the development of p300/CBP degraders

Inhibition of serine and proline racemases by substrate-product analogues

Photolysis of Diacyl Peroxides: A Radical-Based Approach for the Synthesis of Functionalized Amino Acids

Antimicrobial Leucocin Analogues with a Disulfide Bridge Replaced by a Carbocycle or by Noncovalent Interactions of Allyl Glycine Residues

Preparation and Use of Cysteine Orthoesters for Solid-Supported Synthesis of Peptides

Elucidating absolute configuration of unsaturated alcohols via enantioselective acylation reactions

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