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Inhibition of complement C1s improves severe hemolytic anemia in cold agglutinin disease: a first-in-human trial

Blood, 2019-02, Vol.133 (9), p.893-901

2019

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Specific Inhibition of the Classical Complement Pathway Prevents C3 Deposition along the Dermal-Epidermal Junction in Bullous Pemphigoid

Journal of investigative dermatology, 2019-12, Vol.139 (12), p.2417-2424.e2

2019

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The aptamer BT200 effectively inhibits von Willebrand factor (VWF) dependent platelet function after stimulated VWF release by desmopressin or endotoxin

Scientific reports, 2020-07, Vol.10 (1), p.11180-11180, Article 11180

2020

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Combined integrated protocol/basket trial design for a first-in-human trial

Orphanet journal of rare diseases, 2016-10, Vol.11 (1), p.134-134, Article 134

2016

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Defibrotide enhances fibrinolysis in human endotoxemia - a randomized, double blind, crossover trial in healthy volunteers

Scientific reports, 2019-07, Vol.9 (1), p.11136-9, Article 11136

2019

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Pharmacokinetics and pharmacodynamics of low doses of recombinant tissue plasminogen activator to establish a model for biosimilarity comparisons

Research and practice in thrombosis and haemostasis, 2024-08, Vol.8 (6), p.102518, Article 102518

2024

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Assessment of platelets and the endothelium in patients presenting with acute coronary syndromes--is there a future?

Thrombosis and haemostasis, 2009-12, Vol.102 (6), p.1144

2009

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Plasmatic tissue factor pathway inhibitor is a major determinant of clotting in factor VIII inhibited plasma or blood

Thrombosis and haemostasis, 2013-03, Vol.109 (3), p.450

2013

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Morphine Decreases Clopidogrel Concentrations and Effects

Journal of the American College of Cardiology, 2014-02, Vol.63 (7), p.630-635

2014

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Disseminated intravascular coagulation in heat stroke: A hot topic

Critical care medicine, 2012-04, Vol.40 (4), p.1370-1372

2012

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Factors influencing the accuracy of oscillometric blood pressure measurement in critically ill patients

Critical care medicine, 2003-03, Vol.31 (3), p.793-799

2003

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Variable inhibition of high-shear–induced platelet plug formation by eptifibatide and tirofiban under conditions of platelet activation and high von willebrand release: a randomized, placebo-controlled, clinical trial

The American heart journal, 2004-04, Vol.147 (4), p.697-697

2004

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Evaluation of antiinflammatory and antiadhesive effects of heparins in human endotoxemia

Critical care medicine, 2003-04, Vol.31 (4), p.1108-1112

2003

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Morphine Decreases Clopidogrel Concentrations and Effects: A Randomized, Double-Blind, Placebo-Controlled Trial

Journal of the American College of Cardiology, 2014-02, Vol.63 (7), p.630-635

2014

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Micellar Curcumin: Pharmacokinetics and Effects on Inflammation Markers and PCSK‐9 Concentrations in Healthy Subjects in a Double‐Blind, Randomized, Active‐Controlled, Crossover Trial

Molecular nutrition & food research, 2022-11, Vol.66 (22), p.e2200139-n/a

2022

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Optimisation of dose level and vaccination schedule for the VLA15 Lyme borreliosis vaccine candidate among healthy adults: two randomised, observer-blind, placebo-controlled, multicentre, phase 2 studies

The Lancet infectious diseases, 2024-09, Vol.24 (9), p.1045-1058

2024

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Randomized, Double-Blind, Placebo-Controlled, Single-Ascending-Dose Study of the Penetration of a Monoclonal Antibody Combination (ASN100) Targeting Staphylococcus aureus Cytotoxins in the Lung Epithelial Lining Fluid of Healthy Volunteers

Antimicrobial agents and chemotherapy, 2019-08, Vol.63 (8)

2019

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Safety, tolerability, pharmacokinetics and pharmacodynamics of parenterally administered dutogliptin: A prospective dose‐escalating trial

British journal of clinical pharmacology, 2020-05, Vol.86 (5), p.979-990

2020

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Regulation of protease-activated receptor 1 (PAR1) on platelets and responsiveness to thrombin receptor activating peptide (TRAP) during systemic inflammation in humans

Thrombosis and haemostasis, 2003-11, Vol.90 (5), p.898

2003

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Immunogenicity and safety of an 18-month booster dose of the VLA15 Lyme borreliosis vaccine candidate after primary immunisation in healthy adults in the USA: results of the booster phase of a randomised, controlled, phase 2 trial

The Lancet infectious diseases, 2024-07

2024

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The von Willebrand factor–binding aptamer rondaptivon pegol as a treatment for severe and nonsevere hemophilia A

Blood, 2023-03, Vol.141 (10), p.1147-1158

2023

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Dissociation between systemic and pulmonary anti‐inflammatory effects of dexamethasone in humans

British journal of clinical pharmacology, 2016-05, Vol.81 (5), p.865-877

2016

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Morphine decreases ticagrelor concentrations but not its antiplatelet effects: a randomized trial in healthy volunteers

European journal of clinical investigation, 2016-01, Vol.46 (1), p.7-14

2016

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Morphine interaction with prasugrel: a double-blind, cross-over trial in healthy volunteers

Clinical research in cardiology, 2016-04, Vol.105 (4), p.349-355

2016

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Blockade of GPIIb/IIIa by eptifibatide and tirofiban does not alter tissue factor induced thrombin generation in human endotoxemia

Thrombosis and haemostasis, 2003-12, Vol.90 (6), p.1054

2003

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Inhibition of complement C1s improves severe hemolytic anemia in cold agglutinin disease: a first-in-human trial

Specific Inhibition of the Classical Complement Pathway Prevents C3 Deposition along the Dermal-Epidermal Junction in Bullous Pemphigoid

The aptamer BT200 effectively inhibits von Willebrand factor (VWF) dependent platelet function after stimulated VWF release by desmopressin or endotoxin

Combined integrated protocol/basket trial design for a first-in-human trial

Defibrotide enhances fibrinolysis in human endotoxemia - a randomized, double blind, crossover trial in healthy volunteers

Pharmacokinetics and pharmacodynamics of low doses of recombinant tissue plasminogen activator to establish a model for biosimilarity comparisons

Assessment of platelets and the endothelium in patients presenting with acute coronary syndromes--is there a future?

Plasmatic tissue factor pathway inhibitor is a major determinant of clotting in factor VIII inhibited plasma or blood

Morphine Decreases Clopidogrel Concentrations and Effects

Disseminated intravascular coagulation in heat stroke: A hot topic

Factors influencing the accuracy of oscillometric blood pressure measurement in critically ill patients

Variable inhibition of high-shear–induced platelet plug formation by eptifibatide and tirofiban under conditions of platelet activation and high von willebrand release: a randomized, placebo-controlled, clinical trial

Evaluation of antiinflammatory and antiadhesive effects of heparins in human endotoxemia

Morphine Decreases Clopidogrel Concentrations and Effects: A Randomized, Double-Blind, Placebo-Controlled Trial

Micellar Curcumin: Pharmacokinetics and Effects on Inflammation Markers and PCSK‐9 Concentrations in Healthy Subjects in a Double‐Blind, Randomized, Active‐Controlled, Crossover Trial

Optimisation of dose level and vaccination schedule for the VLA15 Lyme borreliosis vaccine candidate among healthy adults: two randomised, observer-blind, placebo-controlled, multicentre, phase 2 studies

Randomized, Double-Blind, Placebo-Controlled, Single-Ascending-Dose Study of the Penetration of a Monoclonal Antibody Combination (ASN100) Targeting Staphylococcus aureus Cytotoxins in the Lung Epithelial Lining Fluid of Healthy Volunteers

Safety, tolerability, pharmacokinetics and pharmacodynamics of parenterally administered dutogliptin: A prospective dose‐escalating trial

Regulation of protease-activated receptor 1 (PAR1) on platelets and responsiveness to thrombin receptor activating peptide (TRAP) during systemic inflammation in humans

Immunogenicity and safety of an 18-month booster dose of the VLA15 Lyme borreliosis vaccine candidate after primary immunisation in healthy adults in the USA: results of the booster phase of a randomised, controlled, phase 2 trial

The von Willebrand factor–binding aptamer rondaptivon pegol as a treatment for severe and nonsevere hemophilia A

Dissociation between systemic and pulmonary anti‐inflammatory effects of dexamethasone in humans

Morphine decreases ticagrelor concentrations but not its antiplatelet effects: a randomized trial in healthy volunteers

Morphine interaction with prasugrel: a double-blind, cross-over trial in healthy volunteers

Blockade of GPIIb/IIIa by eptifibatide and tirofiban does not alter tissue factor induced thrombin generation in human endotoxemia

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