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Modulating the pharmacokinetics of therapeutic antibodies

Biotechnology letters, 2010-05, Vol.32 (5), p.609-622

2010

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Site-Specific Polysialylation of an Antitumor Single-Chain Fv Fragment

Bioconjugate chemistry, 2009-05, Vol.20 (5), p.924-931

2009

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Characterisation and internalisation of recombinant humanised HMFG-1 antibodies against MUC1

British journal of cancer, 2005-11, Vol.93 (11), p.1257-1266

2005

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A HER2 selective theranostic agent for surgical resection guidance and photodynamic therapy

Photochemical & photobiological sciences, 2016-01, Vol.15 (10), p.1227-1238

2016

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Design, characterization and anti-tumour cytotoxicity of a panel of recombinant, mammalian ribonuclease-based immunotoxins

British journal of cancer, 1998-02, Vol.77 (4), p.537-546

1998

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Targeting enzymes for cancer therapy: old enzymes in new roles

British journal of cancer, 1994-11, Vol.70 (5), p.786-794

1994

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Genetic delivery of enzymes for cancer therapy

Gene therapy, 1995-06, Vol.2 (4), p.235

1995

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A recombinant cytotoxic chimera based on mammalian deoxyribonuclease‐I

International journal of cancer, 2000-05, Vol.86 (4), p.561-569

2000

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DNA vaccination for cancer treatment

Gene therapy, 1995-05, Vol.2 (3), p.173

1995

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Cooperativity Induced by a Single Mutation at the Subunit Interface of a Dimeric Enzyme: Glutathione Reductase

Science (American Association for the Advancement of Science), 1992-11, Vol.258 (5085), p.1140-1143

1992

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Redesigned anti-human placental alkaline phosphatase single-chain Fv: soluble expression, characterization and in vivo tumour targeting

Protein engineering, 1997-01, Vol.10 (1), p.89-98

1997

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Alternative proton donors/acceptors in the catalytic mechanism of the glutathione reductase of Escherichia coli: the role of histidine-439 and tyrosine-99

Biochemistry (Easton), 1989-12, Vol.28 (25), p.9602-9607

1989

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Construction, expression and characterisation of a single chain anti-tumour antibody (scFv)-IL-2 fusion protein

Annals of oncology, 1995-11, Vol.6 (9), p.945-947

1995

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Reductive and Oxidative Half-Reactions of Glutathione Reductase from Escherichia coli

Biochemistry (Easton), 1994-11, Vol.33 (46), p.13888-13895

1994

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PWE-011 Aberrantly glycosylated muc1 as a potential therapeutic target for Barrett's with high grade dysplasia and primary and metastatic oesophageal adenocarcinoma

Gut, 2012-07, Vol.61 (Suppl 2), p.A301-A301

2012

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PWE-011Aberrantly glycosylated muc1 as a potential therapeutic target for Barrett's with high grade dysplasia and primary and metastatic oesophageal adenocarcinoma

Gut, 2012-07, Vol.61 (Suppl 2), p.A301-A301

2012

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PWE-012 In vitro characterisation of aberrantly glycosylated MUC1 binding-PS1 photoimmunoconjugates for oesophageal adenocarcinoma targeted photodynamic therapy in primary and metastatic disease

Gut, 2012-07, Vol.61 (Suppl 2), p.A301

2012

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PWE-012 In vitro characterisation of aberrantly glycosylated MUC1 binding-PS1 photoimmunoconjugates for oesophageal adenocarcinoma targeted photodynamic therapy in primary and metastatic disease: Abstract PWE-012 Figure 1

Gut, 2012-07, Vol.61 (Suppl 2), p.A301-A301

2012

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PWE-013Selective cytotoxicity of aberrantly glycosylated MUC1 binding-PS1 photoimmunoconjugates for oesophageal adenocarcinoma targeted photodynamic therapy in primary and metastatic disease

Gut, 2012-07, Vol.61 (Suppl 2), p.A302-A302

2012

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PWE-013 Selective cytotoxicity of aberrantly glycosylated MUC1 binding-PS1 photoimmunoconjugates for oesophageal adenocarcinoma targeted photodynamic therapy in primary and metastatic disease

Gut, 2012-07, Vol.61 (Suppl 2), p.A302-A302

2012

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PWE-012In vitro characterisation of aberrantly glycosylated MUC1 binding-PS1 photoimmunoconjugates for oesophageal adenocarcinoma targeted photodynamic therapy in primary and metastatic disease

Gut, 2012-07, Vol.61 (Suppl 2), p.A301-A301

2012

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Ligand-targeted receptor-mediated vectors for gene delivery

Expert opinion on therapeutic patents, 1998-01, Vol.8 (1), p.53-69

Deonarain, Mahendra P

1998

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PWE-015 HER2 expression in the Barrett's metaplasia-dysplasia-carcinoma sequence and potential targeting in vitro with the single chain antibody fragment C6.5

Gut, 2012-07, Vol.61 (Suppl 2), p.A302-A303

2012

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PWE-015HER2 expression in the Barrett's metaplasia-dysplasia-carcinoma sequence and potential targeting in vitro with the single chain antibody fragment C6.5

Gut, 2012-07, Vol.61 (Suppl 2), p.A302-A303

2012

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Modulating the pharmacokinetics of therapeutic antibodies

Site-Specific Polysialylation of an Antitumor Single-Chain Fv Fragment

Characterisation and internalisation of recombinant humanised HMFG-1 antibodies against MUC1

A HER2 selective theranostic agent for surgical resection guidance and photodynamic therapy

Design, characterization and anti-tumour cytotoxicity of a panel of recombinant, mammalian ribonuclease-based immunotoxins

Targeting enzymes for cancer therapy: old enzymes in new roles

Genetic delivery of enzymes for cancer therapy

A recombinant cytotoxic chimera based on mammalian deoxyribonuclease‐I

DNA vaccination for cancer treatment

Cooperativity Induced by a Single Mutation at the Subunit Interface of a Dimeric Enzyme: Glutathione Reductase

Redesigned anti-human placental alkaline phosphatase single-chain Fv: soluble expression, characterization and in vivo tumour targeting

Alternative proton donors/acceptors in the catalytic mechanism of the glutathione reductase of Escherichia coli: the role of histidine-439 and tyrosine-99

Construction, expression and characterisation of a single chain anti-tumour antibody (scFv)-IL-2 fusion protein

Reductive and Oxidative Half-Reactions of Glutathione Reductase from Escherichia coli

PWE-011 Aberrantly glycosylated muc1 as a potential therapeutic target for Barrett's with high grade dysplasia and primary and metastatic oesophageal adenocarcinoma

PWE-011Aberrantly glycosylated muc1 as a potential therapeutic target for Barrett's with high grade dysplasia and primary and metastatic oesophageal adenocarcinoma

PWE-012 In vitro characterisation of aberrantly glycosylated MUC1 binding-PS1 photoimmunoconjugates for oesophageal adenocarcinoma targeted photodynamic therapy in primary and metastatic disease

PWE-012 In vitro characterisation of aberrantly glycosylated MUC1 binding-PS1 photoimmunoconjugates for oesophageal adenocarcinoma targeted photodynamic therapy in primary and metastatic disease: Abstract PWE-012 Figure 1

PWE-013Selective cytotoxicity of aberrantly glycosylated MUC1 binding-PS1 photoimmunoconjugates for oesophageal adenocarcinoma targeted photodynamic therapy in primary and metastatic disease

PWE-013 Selective cytotoxicity of aberrantly glycosylated MUC1 binding-PS1 photoimmunoconjugates for oesophageal adenocarcinoma targeted photodynamic therapy in primary and metastatic disease

PWE-012In vitro characterisation of aberrantly glycosylated MUC1 binding-PS1 photoimmunoconjugates for oesophageal adenocarcinoma targeted photodynamic therapy in primary and metastatic disease

Ligand-targeted receptor-mediated vectors for gene delivery

PWE-015 HER2 expression in the Barrett's metaplasia-dysplasia-carcinoma sequence and potential targeting in vitro with the single chain antibody fragment C6.5

PWE-015HER2 expression in the Barrett's metaplasia-dysplasia-carcinoma sequence and potential targeting in vitro with the single chain antibody fragment C6.5

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